Protein Alignment CG4854 and Zfp251

DIOPT Version :10

• Sequence 1: NP_650860.1
• Gene: CG4854 / 42391
• FlyBaseID: FBgn0038766
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: NP_001178840.1
• Gene: Zfp251 / 366954
• RGDID: 1311138
• Length: 633
• Species: Rattus norvegicus
• Alignment Length: 343
• Identity: 90/343 - (26%)
• Similarity: 145/343 - (42%)
• Gaps: 72/343 - (20%)

  Fly    19 PKDESLMPTEPDFPDKIKRCTGVELSESPDWPNRICTSCALLLRAALKLRSLCQQTEKDLKEQKL 83
            ||.|.:...|.:....:....|.|..|       :..||.               |:.::|.:|.
  Rat    59 PKPELISQLEQEEELWVLDLLGAEEPE-------VLRSCG---------------TDSEIKSEKE 101

  Fly    84 QEINIEIVHDEQET-----------KKKTESRDLSKNEATGSDSELEYEYLDSYDVTLESSEDVA 137
            :.|..:...:|.:|           .:.:||::...:|:.|..|:..........|   :.:|..
  Rat   102 RSILNQKCSEEVKTPELSQKFPRANSQASESKEACAHESQGDGSQGSSATQGLKGV---AKKDST 163

  Fly   138 CSADELVSIEPAISAPEESVYSLSPKPVTFEDEDSGQAASFTCNICNNVYSERVKLTNHMKVHSA 202
            ...:.|.....|.||.::.: :.|...||.:...:||.. |.|:|||.::.....|:.|.:.|:.
  Rat   164 VCREHLPENTQASSAFDKHL-NPSQSGVTIQRNKTGQRI-FKCDICNKMFKYNSDLSRHRRSHTG 226

  Fly   203 KKPHECEICHKRFRQTPQLARHMNTHTGNRPYKCD----------------------------YC 239
            :||:||..|.:.|..:..|..|...||||:|:|||                            .|
  Rat   227 EKPYECGPCGRAFTHSSNLILHQRIHTGNKPFKCDECGKTFGLNSYLRLHQRIHTGEKPFGCNEC 291

  Fly   240 DSRFADPSTRIKHQRIHTNERPYKCEFCSRSFGYSNVLRVHLKTHTGERPFSCQYCQKSFSQ--- 301
            ...|:..|:.|:|:.|||.|:||||..|.::|..|..|..|.:.||||:|..|.:|.|:||:
  Rat   292 GKAFSRSSSLIQHRIIHTGEKPYKCNECGKAFSQSPQLTQHQRIHTGEKPHGCSWCGKAFSRNAS 356

  Fly   302 -LHHKNSH--EKSHKRTK 316
             :.|:..|  ||.||.|:
  Rat   357 LIQHQRIHTGEKPHKCTQ 374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4854	NP_650860.1	zf-AD	12..>57	CDD:214871	7/37 (19%)
		C2H2 Zn finger	180..200	CDD:275368	6/19 (32%)
		COG5048	201..>258	CDD:227381	23/84 (27%)
		C2H2 Zn finger	208..228	CDD:275368	5/19 (26%)
		zf-H2C2_2	221..244	CDD:463886	11/50 (22%)
		C2H2 Zn finger	236..256	CDD:275368	7/47 (15%)
		zf-H2C2_2	251..271	CDD:463886	10/19 (53%)
		C2H2 Zn finger	264..284	CDD:275368	6/19 (32%)
		C2H2 Zn finger	292..312	CDD:275368	9/25 (36%)
Zfp251	NP_001178840.1	KRAB	15..75	CDD:214630	4/15 (27%)
		COG5048	82..467	CDD:227381	85/320 (27%)
		C2H2 Zn finger	204..224	CDD:275368	6/19 (32%)
		C2H2 Zn finger	232..252	CDD:275368	5/19 (26%)
		C2H2 Zn finger	260..280	CDD:275368	2/19 (11%)
		C2H2 Zn finger	288..308	CDD:275368	5/19 (26%)
		C2H2 Zn finger	316..336	CDD:275368	6/19 (32%)
		C2H2 Zn finger	344..364	CDD:275368	6/19 (32%)
		C2H2 Zn finger	372..392	CDD:275368	1/3 (33%)
		C2H2 Zn finger	400..420	CDD:275368
		C2H2 Zn finger	428..448	CDD:275368
		C2H2 Zn finger	456..476	CDD:275368
		zf-H2C2_2	469..493	CDD:463886
		C2H2 Zn finger	484..504	CDD:275368
		C2H2 Zn finger	557..577	CDD:275368
		C2H2 Zn finger	585..602	CDD:275368