DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4854 and crol

DIOPT Version :9

Sequence 1:	NP_650860.1	Gene:	CG4854 / 42391	FlyBaseID:	FBgn0038766	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	NP_001245993.1	Gene:	crol / 34592	FlyBaseID:	FBgn0020309	Length:	962	Species:	Drosophila melanogaster

Alignment Length:	135	Identity:	49/135 - (36%)
Similarity:	74/135 - (54%)	Gaps:	0/135 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly   178 FTCNICNNVYSERVKLTNHMKVHSAKKPHECEICHKRFRQTPQLARHMNTHTGNRPYKCDYCDSR 242
            |.|.||...:|.:...|||:..|:.:.||.|:.|.|.|.:...|..|:..|||..|::|.||...
  Fly   417 FRCEICGKSFSRKEHFTNHILWHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKT 481

  Fly   243 FADPSTRIKHQRIHTNERPYKCEFCSRSFGYSNVLRVHLKTHTGERPFSCQYCQKSFSQLHHKNS 307
            |......:.|.|.||.|.|:||.:|:::|...:.:..|::.||||.|..|.||.|:|::..|..:
  Fly   482 FTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTN 546

  Fly   308 HEKSH 312
            |.:.|
  Fly   547 HVRQH 551

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4854	NP_650860.1	zf-AD	12..>57	CDD:285071
		C2H2 Zn finger	180..200	CDD:275368	7/19 (37%)
		zf-H2C2_2	193..217	CDD:290200	10/23 (43%)
		COG5048	201..>258	CDD:227381	19/56 (34%)
		C2H2 Zn finger	208..228	CDD:275368	6/19 (32%)
		zf-H2C2_2	221..244	CDD:290200	9/22 (41%)
		C2H2 Zn finger	236..256	CDD:275368	6/19 (32%)
		zf-H2C2_2	251..273	CDD:290200	10/21 (48%)
		C2H2 Zn finger	264..284	CDD:275368	4/19 (21%)
		zf-H2C2_2	277..301	CDD:290200	11/23 (48%)
		C2H2 Zn finger	292..312	CDD:275368	7/19 (37%)
crol	NP_001245993.1	C2H2 Zn finger	223..243	CDD:275368
		C2H2 Zn finger	251..271	CDD:275368
		C2H2 Zn finger	279..299	CDD:275368
		COG5048	300..723	CDD:227381	49/135 (36%)
		C2H2 Zn finger	307..327	CDD:275368
		C2H2 Zn finger	335..355	CDD:275368
		C2H2 Zn finger	363..383	CDD:275368
		C2H2 Zn finger	391..411	CDD:275368
		C2H2 Zn finger	419..439	CDD:275368	7/19 (37%)
		C2H2 Zn finger	447..467	CDD:275368	6/19 (32%)
		C2H2 Zn finger	475..495	CDD:275368	6/19 (32%)
		C2H2 Zn finger	503..523	CDD:275368	4/19 (21%)
		C2H2 Zn finger	531..551	CDD:275368	7/19 (37%)
		C2H2 Zn finger	559..579	CDD:275368
		C2H2 Zn finger	587..607	CDD:275368
		C2H2 Zn finger	615..636	CDD:275368
		C2H2 Zn finger	644..664	CDD:275368
		C2H2 Zn finger	676..696	CDD:275368
		C2H2 Zn finger	704..722	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23226
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100