DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4854 and CG11696

DIOPT Version :9

Sequence 1:	NP_650860.1	Gene:	CG4854 / 42391	FlyBaseID:	FBgn0038766	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	NP_572731.1	Gene:	CG11696 / 32104	FlyBaseID:	FBgn0030314	Length:	664	Species:	Drosophila melanogaster

Alignment Length:	342	Identity:	73/342 - (21%)
Similarity:	116/342 - (33%)	Gaps:	95/342 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LKCRICLVQPKDESLMPTEPDFPDKIKRCTGVELSESPDWPNRICTSCALLLRAALKLRSL---- 70
            |.|.||..        |.| ||.| :||...||         ..||..........|.|:|
  Fly   300 LDCAICAA--------PLE-DFND-LKRHFRVE---------HDCTGYVKCCNNRYKKRTLYVDH 345

  Fly    71 -----------CQQTEKDLKEQKLQEINIEIVHDEQE-------------TKKKTESRDLSKNEA 111
                       ||...|:...:..|.:::...|.:|:             .||...:..|..::.
  Fly   346 LHCHKDPQYFSCQSCRKNFLNRNSQVMHMLRFHSQQQELVHQCAICEARFAKKFLLTMHLKGHKG 410

  Fly   112 TGSDSELEYEYLDSYDVTLESSEDVACSADELVSIEPAISAPEESVYSLSPKPVTFEDEDSGQAA 176
            |...     |..|:...|..:..:::.....:                              .||
  Fly   411 TERP-----EVCDTCSKTFRTKFELSAHVKRM------------------------------HAA 440

  Fly   177 SFT---CNICNNVYSERVKLTNHMKVHSAKKP---HECEICHKRFRQTPQLARHMNTH---TGNR 232
            .||   |:||...:..:.....|.|......|   .:|.:|.:..|....|.:|:..|   .|:.
  Fly   441 DFTPIICDICGTHFRSKANFLIHKKALHPDGPVAEVQCTLCGRWLRDERSLRKHLARHDDRDGDT 505

  Fly   233 PYKCDYCDSRFADPSTRIKHQRIHTNERPYKCEFCSRSFGYSNVLRVHLKTHTGERPFSCQYCQK 297
            .|:|..|::..:..:....|.|.|.:.:.:||..|.:.|.....|..|:.||||...:.||:|.:
  Fly   506 KYRCLLCNAEKSSRAALSSHMRYHHSAKRHKCSLCDKEFKLPRALAEHMATHTGIDLYQCQFCTR 570

  Fly   298 SFSQLHHKNSHEKSHKR 314
            :|..  |.|.|  :||:
  Fly   571 TFKS--HANMH--NHKK 583

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4854	NP_650860.1	zf-AD	12..>57	CDD:285071	14/44 (32%)
		C2H2 Zn finger	180..200	CDD:275368	5/19 (26%)
		zf-H2C2_2	193..217	CDD:290200	5/26 (19%)
		COG5048	201..>258	CDD:227381	14/62 (23%)
		C2H2 Zn finger	208..228	CDD:275368	5/19 (26%)
		zf-H2C2_2	221..244	CDD:290200	7/25 (28%)
		C2H2 Zn finger	236..256	CDD:275368	4/19 (21%)
		zf-H2C2_2	251..273	CDD:290200	7/21 (33%)
		C2H2 Zn finger	264..284	CDD:275368	5/19 (26%)
		zf-H2C2_2	277..301	CDD:290200	10/23 (43%)
		C2H2 Zn finger	292..312	CDD:275368	7/19 (37%)
CG11696	NP_572731.1	zf-AD	2..78	CDD:285071
		C2H2 Zn finger	332..349	CDD:275368	3/16 (19%)
		C2H2 Zn finger	357..378	CDD:275368	4/20 (20%)
		C2H2 Zn finger	388..408	CDD:275368	3/19 (16%)
		C2H2 Zn finger	417..438	CDD:275368	2/50 (4%)
		C2H2 Zn finger	447..465	CDD:275368	4/17 (24%)
		C2H2 Zn finger	478..498	CDD:275368	5/19 (26%)
		C2H2 Zn finger	509..529	CDD:275368	4/19 (21%)
		C2H2 Zn finger	537..557	CDD:275368	5/19 (26%)
		C2H2 Zn finger	565..583	CDD:275368	8/21 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	0	0.000