DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4854 and Zfp771

DIOPT Version :9

Sequence 1:	NP_650860.1	Gene:	CG4854 / 42391	FlyBaseID:	FBgn0038766	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	XP_008758154.1	Gene:	Zfp771 / 308992	RGDID:	1305903	Length:	358	Species:	Rattus norvegicus

Alignment Length:	265	Identity:	82/265 - (30%)
Similarity:	122/265 - (46%)	Gaps:	60/265 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 QQTEKDLKEQKLQEINIEIVHDEQETKKKTESRDLSKNEATGSDSELEYEYLDSYDVTLESSEDV 136
            ||.|:: :|:::||..:.:|..|:|                  :.|.:||.     |.|:|..|
  Rat    46 QQAEEE-EEEEMQEEMVLLVKGEEE------------------EGEEKYEV-----VKLKSPVD- 85

  Fly   137 ACSADELVSIEPAISAPEESVYSLSPKPVTFEDEDSGQAAS-----------------FTCNICN 184
               ..|:.|..|..||.....::.         .|.|:|.:                 |.|..|.
  Rat    86 ---NKEVASQMPVPSADPARPHAC---------PDCGRAFARRSTLAKHARTHTGERPFACTECG 138

  Fly   185 NVYSERVKLTNHMKVHSAKKPHECEICHKRFRQTPQLARHMNTHTGNRPYKCDYCDSRFADPSTR 249
            ..:|::..||.|.:.|:.::|::|..|.|||.....|.:|...|||.:||.|.:|..|||..|..
  Rat   139 RCFSQKSALTKHGRTHTGERPYQCPECDKRFSAASNLRQHRRRHTGEKPYACAHCGRRFAQSSNY 203

  Fly   250 IKHQRIHTNERPYKCEFCSRSFGYSNVLRVHLKTHTGERPFSCQYCQKSFSQ----LHHKNSH-- 308
            .:|.|:||.|:||.|..|.|:||.|:.|..|.:|||||||::|..|...|:|    ..|:..|
  Rat   204 AQHLRVHTGEKPYACPDCGRAFGGSSCLARHRRTHTGERPYACADCGTRFAQSSALAKHRRVHTG 268

  Fly   309 EKSHK 313
            ||.|:
  Rat   269 EKPHR 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4854	NP_650860.1	zf-AD	12..>57	CDD:285071
		C2H2 Zn finger	180..200	CDD:275368	6/19 (32%)
		zf-H2C2_2	193..217	CDD:290200	10/23 (43%)
		COG5048	201..>258	CDD:227381	22/56 (39%)
		C2H2 Zn finger	208..228	CDD:275368	7/19 (37%)
		zf-H2C2_2	221..244	CDD:290200	10/22 (45%)
		C2H2 Zn finger	236..256	CDD:275368	8/19 (42%)
		zf-H2C2_2	251..273	CDD:290200	11/21 (52%)
		C2H2 Zn finger	264..284	CDD:275368	8/19 (42%)
		zf-H2C2_2	277..301	CDD:290200	12/23 (52%)
		C2H2 Zn finger	292..312	CDD:275368	8/25 (32%)
Zfp771	XP_008758154.1	COG5048	<82..286	CDD:227381	68/205 (33%)
		C2H2 Zn finger	106..126	CDD:275368	3/28 (11%)
		zf-H2C2_2	119..143	CDD:290200	3/23 (13%)
		C2H2 Zn finger	134..154	CDD:275368	6/19 (32%)
		zf-H2C2_2	146..170	CDD:290200	9/23 (39%)
		C2H2 Zn finger	162..182	CDD:275368	7/19 (37%)
		zf-H2C2_2	174..199	CDD:290200	11/24 (46%)
		C2H2 Zn finger	190..210	CDD:275368	8/19 (42%)
		zf-H2C2_2	202..225	CDD:290200	10/22 (45%)
		C2H2 Zn finger	218..238	CDD:275368	8/19 (42%)
		zf-H2C2_2	231..255	CDD:290200	12/23 (52%)
		C2H2 Zn finger	246..266	CDD:275368	5/19 (26%)
		zf-H2C2_2	258..281	CDD:290200	5/16 (31%)
		C2H2 Zn finger	274..294	CDD:275368	82/265 (31%)
		zf-H2C2_2	286..309	CDD:290200
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	139	1.000	Inparanoid score	I4420
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.960