Protein Alignment CG4854 and Zkscan3

DIOPT Version :10

• Sequence 1: NP_650860.1
• Gene: CG4854 / 42391
• FlyBaseID: FBgn0038766
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: NP_001012053.2
• Gene: Zkscan3 / 306977
• RGDID: 1305753
• Length: 553
• Species: Rattus norvegicus
• Alignment Length: 346
• Identity: 96/346 - (27%)
• Similarity: 150/346 - (43%)
• Gaps: 58/346 - (16%)

  Fly    14 ICLVQPKDESLMPTEPDFPDKIKRCTGVELSESPDWPNRICTSCALLLRAALKLRSLCQQTEKDL 78
            :.|::..|..|..|.|..||            ..|....:|:...||..|.....|..:..|..|
  Rat   123 VALLEYLDRQLDETPPQVPD------------DDDGQELLCSKAVLLTSAQGSESSQMESMEPLL 175

  Fly    79 KEQKLQEINIEI-----VHDEQE----TKKKTESRDLSKNE--ATGSD---SELEYEYLDSYDVT 129
            |::.|..:..|:     .|..::    |:..:|.:.|.|.|  |.|..   :|.:...::.|...
  Rat   176 KQESLGSLPSEVRVTQAGHCGEDGVTATRLTSELQGLLKMEDVAPGLSPRWTEQDSSQMNLYKDE 240

  Fly   130 LESSEDVACSADE-----LVSIEPAISAPEESVYSLSPKPVTFEDED-----SGQAAS------- 177
            ::.:.....|.||     :..:.||    ||:......:.|.|..||     :|..||
  Rat   241 MQENSGSLVSLDENMQTKVRDLPPA----EENTEQKPEQTVCFLGEDTVQIPTGTEASEQEGKLQ 301

  Fly   178 -----------FTCNICNNVYSERVKLTNHMKVHSAKKPHECEICHKRFRQTPQLARHMNTHTGN 231
                       |.|..|...:::...|:.|.::|:..||:|||.|.|.|..:..|..|...|||.
  Rat   302 TTQKNATGNRRFYCRECGKSFAQSSGLSKHKRIHTGLKPYECEECGKAFIGSSALIIHQRVHTGE 366

  Fly   232 RPYKCDYCDSRFADPSTRIKHQRIHTNERPYKCEFCSRSFGYSNVLRVHLKTHTGERPFSCQYCQ 296
            :||:|:.|...|:..|..|||||.||.|:||:|:.|.::|..|..|..|.:.||||:|:.|..|.
  Rat   367 KPYECEECGKAFSHSSDLIKHQRTHTGEKPYECDDCGKTFTQSCSLLEHHRIHTGEKPYQCNMCP 431

  Fly   297 KSFSQLHHKNSHEKSHKRTKE 317
            |:|.:..|...|:::|...|:
  Rat   432 KAFRRSSHLLRHQRTHTGDKD 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4854	NP_650860.1	zf-AD	12..>57	CDD:214871	9/42 (21%)
		C2H2 Zn finger	180..200	CDD:275368	4/19 (21%)
		COG5048	201..>258	CDD:227381	25/56 (45%)
		C2H2 Zn finger	208..228	CDD:275368	7/19 (37%)
		zf-H2C2_2	221..244	CDD:463886	9/22 (41%)
		C2H2 Zn finger	236..256	CDD:275368	9/19 (47%)
		zf-H2C2_2	251..271	CDD:463886	11/19 (58%)
		C2H2 Zn finger	264..284	CDD:275368	6/19 (32%)
		C2H2 Zn finger	292..312	CDD:275368	6/19 (32%)
Zkscan3	NP_001012053.2	SCAN	47..159	CDD:128708	11/47 (23%)
		KRAB	213..271	CDD:214630	13/61 (21%)
		zf-C2H2	313..335	CDD:395048	5/21 (24%)
		C2H2 Zn finger	315..335	CDD:275368	4/19 (21%)
		zf-H2C2_2	328..350	CDD:463886	10/21 (48%)
		zf-C2H2	341..363	CDD:395048	8/21 (38%)
		C2H2 Zn finger	343..363	CDD:275368	7/19 (37%)
		COG5048	<367..514	CDD:227381	35/86 (41%)
		C2H2 Zn finger	371..391	CDD:275368	9/19 (47%)
		C2H2 Zn finger	399..419	CDD:275368	6/19 (32%)
		C2H2 Zn finger	427..447	CDD:275368	6/19 (32%)
		C2H2 Zn finger	481..501	CDD:275368
		zf-C2H2	507..529	CDD:395048
		C2H2 Zn finger	509..529	CDD:275368