DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4854 and Zfp287

DIOPT Version :9

Sequence 1:	NP_650860.1	Gene:	CG4854 / 42391	FlyBaseID:	FBgn0038766	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	NP_001100478.1	Gene:	Zfp287 / 303212	RGDID:	1308617	Length:	762	Species:	Rattus norvegicus

Alignment Length:	136	Identity:	55/136 - (40%)
Similarity:	83/136 - (61%)	Gaps:	0/136 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly   177 SFTCNICNNVYSERVKLTNHMKVHSAKKPHECEICHKRFRQTPQLARHMNTHTGNRPYKCDYCDS 241
            |:.||:|...:|:...||.|.:.|:.:||::|.:|.|.|.|:..|.:|...|.|.:|:||:.|..
  Rat   589 SYICNVCGKAFSQSANLTQHHRTHTGEKPYKCSVCGKAFSQSVHLTQHQRIHNGEKPFKCNTCGK 653

  Fly   242 RFADPSTRIKHQRIHTNERPYKCEFCSRSFGYSNVLRVHLKTHTGERPFSCQYCQKSFSQLHHKN 306
            .:...:...:|||:||.|:||||..|.::|.||:.|..|.:|||||||:.|.:|.|.|||.....
  Rat   654 AYRQGANLTQHQRVHTGEKPYKCHHCGKAFIYSSSLNQHRRTHTGERPYKCTHCNKDFSQRTCLI 718

  Fly   307 SHEKSH 312
            .|::.|
  Rat   719 QHQRIH 724

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4854	NP_650860.1	zf-AD	12..>57	CDD:285071
		C2H2 Zn finger	180..200	CDD:275368	7/19 (37%)
		zf-H2C2_2	193..217	CDD:290200	10/23 (43%)
		COG5048	201..>258	CDD:227381	19/56 (34%)
		C2H2 Zn finger	208..228	CDD:275368	7/19 (37%)
		zf-H2C2_2	221..244	CDD:290200	8/22 (36%)
		C2H2 Zn finger	236..256	CDD:275368	5/19 (26%)
		zf-H2C2_2	251..273	CDD:290200	12/21 (57%)
		C2H2 Zn finger	264..284	CDD:275368	7/19 (37%)
		zf-H2C2_2	277..301	CDD:290200	13/23 (57%)
		C2H2 Zn finger	292..312	CDD:275368	7/19 (37%)
Zfp287	NP_001100478.1	SCAN	46..133	CDD:280241
		KRAB	168..225	CDD:214630
		KRAB	168..207	CDD:279668
		C2H2 Zn finger	368..388	CDD:275368
		zf-C2H2	394..416	CDD:278523
		C2H2 Zn finger	396..416	CDD:275368
		zf-H2C2_2	408..433	CDD:290200
		COG5048	420..752	CDD:227381	55/136 (40%)
		C2H2 Zn finger	424..444	CDD:275368
		zf-H2C2_2	436..461	CDD:290200
		C2H2 Zn finger	452..472	CDD:275368
		zf-H2C2_2	464..489	CDD:290200
		C2H2 Zn finger	480..500	CDD:275368
		zf-H2C2_2	492..517	CDD:290200
		C2H2 Zn finger	508..528	CDD:275368
		zf-H2C2_2	520..545	CDD:290200
		C2H2 Zn finger	536..556	CDD:275368
		zf-H2C2_2	548..573	CDD:290200
		C2H2 Zn finger	564..584	CDD:275368
		zf-C2H2	590..612	CDD:278523	7/21 (33%)
		C2H2 Zn finger	592..612	CDD:275368	7/19 (37%)
		zf-H2C2_2	604..629	CDD:290200	10/24 (42%)
		C2H2 Zn finger	620..640	CDD:275368	7/19 (37%)
		zf-H2C2_2	632..657	CDD:290200	8/24 (33%)
		C2H2 Zn finger	648..668	CDD:275368	5/19 (26%)
		zf-H2C2_2	660..685	CDD:290200	12/24 (50%)
		C2H2 Zn finger	676..696	CDD:275368	7/19 (37%)
		zf-H2C2_2	688..713	CDD:290200	13/24 (54%)
		C2H2 Zn finger	704..724	CDD:275368	7/19 (37%)
		zf-H2C2_2	717..741	CDD:290200	2/8 (25%)
		C2H2 Zn finger	732..752	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000