DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4854 and ace2

DIOPT Version :9

Sequence 1:	NP_650860.1	Gene:	CG4854 / 42391	FlyBaseID:	FBgn0038766	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	NP_594109.1	Gene:	ace2 / 2541661	PomBaseID:	SPAC6G10.12c	Length:	533	Species:	Schizosaccharomyces pombe

Alignment Length:	180	Identity:	48/180 - (26%)
Similarity:	84/180 - (46%)	Gaps:	32/180 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   149 AISAPEES-VYSLSPKP-VTFEDEDSGQAASFTCNICNNVYSERVKLTNHMKVHSAKKP------ 205
            |:|||.|| :.:..|:| :|.::|:         .:...:.|..:.:|..:..|.:|.|
pombe   355 ALSAPYESCIVTKKPEPCITVKEEE---------QLAPKIESADLSITPQVTEHDSKPPVRISYD 410

  Fly   206 HECEICHKRFRQTPQLAR-----HMNTHTG---NRPYKCDY--CDSRFADPSTRIKHQRIHTNER 260
            |.|    |..:|:.::.|     ..:.:.|   :..|.|.|  |:.|.|.......|.:.|.::|
pombe   411 HRC----KTRKQSTRICRIPPETMASLYCGPEADGKYVCLYNGCNKRIARKYNVESHIQTHLSDR 471

  Fly   261 PYKCEFCSRSFGYSNVLRVHLKTHTGERPFSCQYCQKSFSQLHHKNSHEK 310
            ||:|:.|...|...:.|:.||:.|...||:.|: |.|.|::|...|.|::
pombe   472 PYRCDLCKAGFVRHHDLKRHLRIHENGRPYVCE-CLKRFNRLDALNRHKQ 520

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4854	NP_650860.1	zf-AD	12..>57	CDD:285071
		C2H2 Zn finger	180..200	CDD:275368	2/19 (11%)
		zf-H2C2_2	193..217	CDD:290200	7/29 (24%)
		COG5048	201..>258	CDD:227381	16/72 (22%)
		C2H2 Zn finger	208..228	CDD:275368	4/24 (17%)
		zf-H2C2_2	221..244	CDD:290200	7/32 (22%)
		C2H2 Zn finger	236..256	CDD:275368	6/21 (29%)
		zf-H2C2_2	251..273	CDD:290200	8/21 (38%)
		C2H2 Zn finger	264..284	CDD:275368	6/19 (32%)
		zf-H2C2_2	277..301	CDD:290200	10/23 (43%)
		C2H2 Zn finger	292..312	CDD:275368	7/19 (37%)
ace2	NP_594109.1	COG5048	45..518	CDD:227381	47/176 (27%)
		C2H2 Zn finger	448..467	CDD:275368	4/18 (22%)
		zf-C2H2	473..495	CDD:278523	7/21 (33%)
		C2H2 Zn finger	475..495	CDD:275368	6/19 (32%)
		zf-H2C2_2	487..511	CDD:290200	10/24 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	84	1.000	Inparanoid score	I1804
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050