DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4854 and Zfp771

DIOPT Version :9

Sequence 1:	NP_650860.1	Gene:	CG4854 / 42391	FlyBaseID:	FBgn0038766	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	NP_796336.1	Gene:	Zfp771 / 244216	MGIID:	2442050	Length:	317	Species:	Mus musculus

Alignment Length:	265	Identity:	81/265 - (30%)
Similarity:	122/265 - (46%)	Gaps:	60/265 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 QQTEKDLKEQKLQEINIEIVHDEQETKKKTESRDLSKNEATGSDSELEYEYLDSYDVTLESSEDV 136
            ||.|:: :|:::||..:.:|..|:|                  :.|.:||.     |.|:    :
Mouse     5 QQAEEE-EEEEMQEEMVLLVKGEEE------------------EGEEKYEV-----VKLK----I 41

  Fly   137 ACSADELVSIEPAISAPEESVYSLSPKPVTFEDEDSGQAAS-----------------FTCNICN 184
            .....|:.|..||.||.....::.         .|.|:|.:                 |.|..|.
Mouse    42 PVDNKEVASQMPAPSADPARPHAC---------PDCGRAFARRSTLAKHARTHTGERPFACTECG 97

  Fly   185 NVYSERVKLTNHMKVHSAKKPHECEICHKRFRQTPQLARHMNTHTGNRPYKCDYCDSRFADPSTR 249
            ..:|::..||.|.:.|:.::|::|..|.|||.....|.:|...|||.:||.|.:|..|||..|..
Mouse    98 RCFSQKSALTKHGRTHTGERPYQCPECDKRFSAASNLRQHRRRHTGEKPYACAHCGRRFAQSSNY 162

  Fly   250 IKHQRIHTNERPYKCEFCSRSFGYSNVLRVHLKTHTGERPFSCQYCQKSFSQ----LHHKNSH-- 308
            .:|.|:||.|:||.|..|.|:||.|:.|..|.:|||||||::|..|...|:|    ..|:..|
Mouse   163 AQHLRVHTGEKPYACPDCGRAFGGSSCLARHRRTHTGERPYACADCGTRFAQSSALAKHRRVHTG 227

  Fly   309 EKSHK 313
            ||.|:
Mouse   228 EKPHR 232

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4854	NP_650860.1	zf-AD	12..>57	CDD:285071
		C2H2 Zn finger	180..200	CDD:275368	6/19 (32%)
		zf-H2C2_2	193..217	CDD:290200	10/23 (43%)
		COG5048	201..>258	CDD:227381	22/56 (39%)
		C2H2 Zn finger	208..228	CDD:275368	7/19 (37%)
		zf-H2C2_2	221..244	CDD:290200	10/22 (45%)
		C2H2 Zn finger	236..256	CDD:275368	8/19 (42%)
		zf-H2C2_2	251..273	CDD:290200	11/21 (52%)
		C2H2 Zn finger	264..284	CDD:275368	8/19 (42%)
		zf-H2C2_2	277..301	CDD:290200	12/23 (52%)
		C2H2 Zn finger	292..312	CDD:275368	8/25 (32%)
Zfp771	NP_796336.1	C2H2 Zn finger	65..85	CDD:275368	3/28 (11%)
		COG5048	<90..245	CDD:227381	58/143 (41%)
		C2H2 Zn finger	93..113	CDD:275368	6/19 (32%)
		C2H2 Zn finger	121..141	CDD:275368	7/19 (37%)
		C2H2 Zn finger	149..169	CDD:275368	8/19 (42%)
		C2H2 Zn finger	177..197	CDD:275368	8/19 (42%)
		C2H2 Zn finger	205..225	CDD:275368	5/19 (26%)
		C2H2 Zn finger	233..253	CDD:275368	81/265 (31%)
		zf-H2C2_2	245..269	CDD:404364
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	140	1.000	Inparanoid score	I4481
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.960