DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4854 and Zfp62

DIOPT Version :9

Sequence 1:	NP_650860.1	Gene:	CG4854 / 42391	FlyBaseID:	FBgn0038766	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	NP_001349654.1	Gene:	Zfp62 / 22720	MGIID:	99662	Length:	914	Species:	Mus musculus

Alignment Length:	303	Identity:	77/303 - (25%)
Similarity:	131/303 - (43%)	Gaps:	66/303 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 CTSCA---LLLRAALKLRSL--------CQQTEKDLKEQKLQEINIEIVHDEQETKKKTESRDLS 107
            |..|.   :..|..|..:|:        |.:.||......|. |..:::|..::..:..|.....
Mouse   301 CDECGKAFITCRTLLNHKSIHFGDKPYKCDECEKSFNYSSLL-IQHKVIHTGEKPYECDECGKAF 364

  Fly   108 KNEA---------TGSDSELEYEYLDSYDVTLESSEDVACSADELVSIEPAISAPEESVYSLSPK 163
            :|.:         ||   |..|:.            |:...|   .|....::..:    |:.|.
Mouse   365 RNSSGLIVHKRIHTG---EKPYKC------------DICGKA---FSYSSGLAVHK----SIHPG 407

  Fly   164 PVTFEDEDSGQAAS-----------------FTCNICNNVYSERVKLTNHMKVHSAKKPHECEIC 211
            ....|.:|.|::.|                 :.|::|...:.....|..|.::|:.:||::|::|
Mouse   408 KKAHECKDCGKSFSYNSLLLQHKTIHTGERPYVCDVCGKTFRNNSGLKVHRRLHTGEKPYKCDVC 472

  Fly   212 HKRFRQTPQLARHMNTHTGNRPYKCDYCDSRFADPSTRIKHQRIHTNERPYKCEFCSRSFGYSNV 276
            .|.:.....|..|...|.|.:||||.||:..|...|...:|:||||.|:|:.|:.|.::|..::.
Mouse   473 GKAYISRSSLKNHKGIHMGEKPYKCSYCEKSFNYSSALEQHKRIHTREKPFGCDECGKAFRNNSG 537

  Fly   277 LRVHLKTHTGERPFSCQYCQKSF----SQLHHKNSH--EKSHK 313
            |:||.:.||||||:.|:.|.|::    |.::||:.|  ||..|
Mouse   538 LKVHKRIHTGERPYKCEECGKAYISLSSLINHKSVHPGEKPFK 580

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4854	NP_650860.1	zf-AD	12..>57	CDD:285071	1/2 (50%)
		C2H2 Zn finger	180..200	CDD:275368	4/19 (21%)
		zf-H2C2_2	193..217	CDD:290200	8/23 (35%)
		COG5048	201..>258	CDD:227381	21/56 (38%)
		C2H2 Zn finger	208..228	CDD:275368	5/19 (26%)
		zf-H2C2_2	221..244	CDD:290200	10/22 (45%)
		C2H2 Zn finger	236..256	CDD:275368	7/19 (37%)
		zf-H2C2_2	251..273	CDD:290200	10/21 (48%)
		C2H2 Zn finger	264..284	CDD:275368	6/19 (32%)
		zf-H2C2_2	277..301	CDD:290200	12/27 (44%)
		C2H2 Zn finger	292..312	CDD:275368	9/25 (36%)
Zfp62	NP_001349654.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..35
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	80..101
		COG5048	127..542	CDD:227381	60/263 (23%)
		C2H2 Zn finger	133..153	CDD:275368
		C2H2 Zn finger	161..181	CDD:275368
		C2H2 Zn finger	189..209	CDD:275368
		C2H2 Zn finger	217..237	CDD:275368
		C2H2 Zn finger	245..265	CDD:275368
		C2H2 Zn finger	273..293	CDD:275368
		C2H2 Zn finger	301..321	CDD:275368	5/19 (26%)
		C2H2 Zn finger	329..349	CDD:275368	5/20 (25%)
		C2H2 Zn finger	357..377	CDD:275368	2/19 (11%)
		SFP1	<379..458	CDD:227516	15/100 (15%)
		C2H2 Zn finger	385..405	CDD:275368	4/38 (11%)
		C2H2 Zn finger	413..433	CDD:275368	3/19 (16%)
		COG5048	437..850	CDD:227381	51/144 (35%)
		C2H2 Zn finger	441..461	CDD:275368	4/19 (21%)
		C2H2 Zn finger	469..489	CDD:275368	5/19 (26%)
		C2H2 Zn finger	497..517	CDD:275368	7/19 (37%)
		C2H2 Zn finger	525..545	CDD:275368	6/19 (32%)
		C2H2 Zn finger	553..573	CDD:275368	6/19 (32%)
		C2H2 Zn finger	581..601	CDD:275368	77/303 (25%)
		C2H2 Zn finger	609..629	CDD:275368
		C2H2 Zn finger	637..657	CDD:275368
		C2H2 Zn finger	665..685	CDD:275368
		C2H2 Zn finger	693..713	CDD:275368
		C2H2 Zn finger	721..741	CDD:275368
		C2H2 Zn finger	749..769	CDD:275368
		C2H2 Zn finger	777..797	CDD:275368
		C2H2 Zn finger	805..824	CDD:275368
		C2H2 Zn finger	832..852	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000