DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4854 and pag-3

DIOPT Version :9

Sequence 1:	NP_650860.1	Gene:	CG4854 / 42391	FlyBaseID:	FBgn0038766	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	NP_510480.1	Gene:	pag-3 / 181588	WormBaseID:	WBGene00003909	Length:	336	Species:	Caenorhabditis elegans

Alignment Length:	161	Identity:	56/161 - (34%)
Similarity:	86/161 - (53%)	Gaps:	7/161 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   152 APEESVYSLSPKPVTFEDEDSGQAASFTCNICNNVYSERVKLTNHMKVHSAKKPHECEICHKRFR 216
            :|..||::.:|.|..       :...|.|..|..::|....|..|.:||.:.|..||:.|.|.|:
Worm   107 SPSASVWNRTPTPPV-------EIKPFHCQKCTKLFSTIAALEQHQQVHVSDKQFECKQCGKTFK 164

  Fly   217 QTPQLARHMNTHTGNRPYKCDYCDSRFADPSTRIKHQRIHTNERPYKCEFCSRSFGYSNVLRVHL 281
            ::..|:.|:..|:..|||.|:||..||...|...||..|||.|:|:||..|.::|..|:.|..|.
Worm   165 RSSTLSTHLLIHSDTRPYPCEYCGKRFHQKSDMKKHTYIHTGEKPHKCTVCGKAFSQSSNLITHT 229

  Fly   282 KTHTGERPFSCQYCQKSFSQLHHKNSHEKSH 312
            :.|||.:||:|..|.::|.:...:..|.:||
Worm   230 RKHTGFKPFACDVCGRTFQRKVDRRRHRESH 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4854	NP_650860.1	zf-AD	12..>57	CDD:285071
		C2H2 Zn finger	180..200	CDD:275368	5/19 (26%)
		zf-H2C2_2	193..217	CDD:290200	10/23 (43%)
		COG5048	201..>258	CDD:227381	22/56 (39%)
		C2H2 Zn finger	208..228	CDD:275368	6/19 (32%)
		zf-H2C2_2	221..244	CDD:290200	10/22 (45%)
		C2H2 Zn finger	236..256	CDD:275368	8/19 (42%)
		zf-H2C2_2	251..273	CDD:290200	11/21 (52%)
		C2H2 Zn finger	264..284	CDD:275368	6/19 (32%)
		zf-H2C2_2	277..301	CDD:290200	10/23 (43%)
		C2H2 Zn finger	292..312	CDD:275368	4/19 (21%)
pag-3	NP_510480.1	C2H2 Zn finger	128..148	CDD:275368	5/19 (26%)
		zf-H2C2_2	140..165	CDD:290200	10/24 (42%)
		zf-C2H2	154..176	CDD:278523	7/21 (33%)
		C2H2 Zn finger	156..176	CDD:275368	6/19 (32%)
		COG5048	164..>233	CDD:227381	26/68 (38%)
		zf-H2C2_2	169..193	CDD:290200	11/23 (48%)
		C2H2 Zn finger	184..204	CDD:275368	8/19 (42%)
		zf-H2C2_2	196..221	CDD:290200	11/24 (46%)
		C2H2 Zn finger	212..232	CDD:275368	6/19 (32%)
		zf-H2C2_2	224..247	CDD:290200	9/22 (41%)
		C2H2 Zn finger	240..260	CDD:275368	4/19 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2318
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.860