DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4854 and M03D4.4

DIOPT Version :9

Sequence 1:	NP_650860.1	Gene:	CG4854 / 42391	FlyBaseID:	FBgn0038766	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	NP_001023313.1	Gene:	M03D4.4 / 177375	WormBaseID:	WBGene00019751	Length:	505	Species:	Caenorhabditis elegans

Alignment Length:	199	Identity:	64/199 - (32%)
Similarity:	98/199 - (49%)	Gaps:	20/199 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   119 EYEYLDSYDVTLESSEDVACSADELVSIEPAISAPEESVY-------SLSPKPVT-FEDEDSGQA 175
            |:|.::..|...:..||   .:|||..|:..|   |:|.:       .||..|.| .|...||:.
Worm    27 EHETVEQGDQEEDRMED---DSDELAMIKIKI---EDSDFLSDTDSSQLSMNPTTPSEKSSSGEK 85

  Fly   176 ASFTCNICNNVYSERVKLTNHMKVHSAKKPHECEICHKRFRQTPQLARHMNTHTGNRPYKCDYCD 240
            ..:.|..|:.:::.:.:|..||::||.::||.|..|.|.|.....|.:|...|||.|.:.|.:|:
Worm    86 GRYECEDCHEMFAVKRELATHMRIHSGEQPHSCTQCGKEFGTRQLLKKHWMWHTGERSHVCPHCN 150

  Fly   241 SRFADPSTRIKHQRIHTNERPYKCEFCSRSFGYSNVLRVHLKTHTGERPFSCQYCQKSFSQL--- 302
            ..|.......:|..||:..||::|..|.::|.:...|..|:|.|. ||.||||.|.:||.:.
Worm   151 KAFFQKGHLTQHLMIHSGGRPHECPQCHKTFIFKFDLNRHMKIHQ-ERGFSCQQCGRSFLKQVML 214

  Fly   303 --HH 304
              ||
Worm   215 DEHH 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4854	NP_650860.1	zf-AD	12..>57	CDD:285071
		C2H2 Zn finger	180..200	CDD:275368	5/19 (26%)
		zf-H2C2_2	193..217	CDD:290200	11/23 (48%)
		COG5048	201..>258	CDD:227381	19/56 (34%)
		C2H2 Zn finger	208..228	CDD:275368	6/19 (32%)
		zf-H2C2_2	221..244	CDD:290200	8/22 (36%)
		C2H2 Zn finger	236..256	CDD:275368	4/19 (21%)
		zf-H2C2_2	251..273	CDD:290200	8/21 (38%)
		C2H2 Zn finger	264..284	CDD:275368	6/19 (32%)
		zf-H2C2_2	277..301	CDD:290200	13/23 (57%)
		C2H2 Zn finger	292..312	CDD:275368	7/18 (39%)
M03D4.4	NP_001023313.1	C2H2 Zn finger	90..110	CDD:275368	5/19 (26%)
		zf-H2C2_2	102..127	CDD:290200	11/24 (46%)
		C2H2 Zn finger	118..138	CDD:275368	6/19 (32%)
		C2H2 Zn finger	146..166	CDD:275368	4/19 (21%)
		zf-H2C2_2	158..181	CDD:290200	7/22 (32%)
		zf-C2H2	172..194	CDD:278523	6/21 (29%)
		C2H2 Zn finger	174..194	CDD:275368	6/19 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000