DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG4854 and ZNF570

DIOPT Version :9

Sequence 1:NP_650860.1 Gene:CG4854 / 42391 FlyBaseID:FBgn0038766 Length:319 Species:Drosophila melanogaster
Sequence 2:NP_001287922.1 Gene:ZNF570 / 148268 HGNCID:26416 Length:592 Species:Homo sapiens


Alignment Length:289 Identity:84/289 - (29%)
Similarity:126/289 - (43%) Gaps:89/289 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    70 LCQQTEKDL-KEQKLQEINIEIVHDEQETKKKTESRDLSKNEATGSDSELEYEYLDSYDVTLESS 133
            ||  |:|.: ||:|:.:      ||       |:.|...||                        
Human   233 LC--TQKIIPKEEKVHK------HD-------TQKRSFKKN------------------------ 258

  Fly   134 EDVACSADELVSIEPAISAPE---------ESVYSLS------------PKPVTFEDEDSGQAAS 177
                     |::|:|.....|         |.|:|.|            .||  ::..:.|:|.|
Human   259 ---------LMAIKPKSVCAEKKLLKCNDCEKVFSQSSSLTLHQRIHTGEKP--YKCIECGKAFS 312

  Fly   178 -----------------FTCNICNNVYSERVKLTNHMKVHSAKKPHECEICHKRFRQTPQLARHM 225
                             :.|..|...:|:...|..|::||:.:||:||::|.|.|.|...||:|.
Human   313 QRSNLVQHQRIHTGEKPYECKECRKAFSQNAHLVQHLRVHTGEKPYECKVCRKAFSQFAYLAQHQ 377

  Fly   226 NTHTGNRPYKCDYCDSRFADPSTRIKHQRIHTNERPYKCEFCSRSFGYSNVLRVHLKTHTGERPF 290
            ..|||.:||:|..|...|::.|:..:|||:||.|:||:|..|.::|.....|.||.:.||||||:
Human   378 RVHTGEKPYECIECGKAFSNRSSIAQHQRVHTGEKPYECNVCGKAFSLRAYLTVHQRIHTGERPY 442

  Fly   291 SCQYCQKSFSQLHHKNSHEKSHKRTKEVK 319
            .|:.|.|:|||..|...|::.|...|..|
Human   443 ECKECGKAFSQNSHLAQHQRIHTGEKPYK 471

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4854NP_650860.1 zf-AD 12..>57 CDD:285071
C2H2 Zn finger 180..200 CDD:275368 5/19 (26%)
zf-H2C2_2 193..217 CDD:290200 11/23 (48%)
COG5048 201..>258 CDD:227381 24/56 (43%)
C2H2 Zn finger 208..228 CDD:275368 8/19 (42%)
zf-H2C2_2 221..244 CDD:290200 10/22 (45%)
C2H2 Zn finger 236..256 CDD:275368 7/19 (37%)
zf-H2C2_2 251..273 CDD:290200 11/21 (52%)
C2H2 Zn finger 264..284 CDD:275368 6/19 (32%)
zf-H2C2_2 277..301 CDD:290200 13/23 (57%)
C2H2 Zn finger 292..312 CDD:275368 8/19 (42%)
ZNF570NP_001287922.1 KRAB 70..130 CDD:214630
C2H2 Zn finger 276..296 CDD:275368 4/19 (21%)
zf-H2C2_2 288..313 CDD:316026 4/26 (15%)
C2H2 Zn finger 304..324 CDD:275368 3/19 (16%)
COG5048 <307..572 CDD:227381 61/165 (37%)
C2H2 Zn finger 332..352 CDD:275368 5/19 (26%)
C2H2 Zn finger 360..380 CDD:275368 8/19 (42%)
C2H2 Zn finger 388..408 CDD:275368 7/19 (37%)
C2H2 Zn finger 416..436 CDD:275368 6/19 (32%)
C2H2 Zn finger 444..464 CDD:275368 8/19 (42%)
C2H2 Zn finger 472..492 CDD:275368 84/289 (29%)
C2H2 Zn finger 500..520 CDD:275368
C2H2 Zn finger 528..548 CDD:275368
C2H2 Zn finger 556..576 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

Return to query results.
Submit another query.