DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4854 and Zfp853

DIOPT Version :9

Sequence 1:	NP_650860.1	Gene:	CG4854 / 42391	FlyBaseID:	FBgn0038766	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	XP_038945781.1	Gene:	Zfp853 / 102555274	RGDID:	1563095	Length:	857	Species:	Rattus norvegicus

Alignment Length:	341	Identity:	92/341 - (26%)
Similarity:	145/341 - (42%)	Gaps:	59/341 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 QPKDESLM--PTEPDFPDKIKRCTGVELS------ESPDWPNRICTSCALLLRAALKLRSLCQQT 74
            |.:.:.|.  |.||: .::.|...||||.      .|.....|:.....|.|:...:||.|.:..
  Rat   494 QQRHQQLQPPPLEPE-EEEEKEEEGVELELMPVDIRSEQELERLQEQRQLQLKLQEQLRQLEEHL 557

  Fly    75 EKDLKEQKLQEINIEIVHDEQETKKKTESRDLSKNEA--------------------TGSDSELE 119
            |:..:.::||...:|.:...|:.:::.|...|.:.|.                    |....||:
  Rat   558 EQQQQMEQLQLQQMEQLEQLQQQQQQMEQLQLEQQEVHLELTPVELDAQQEELQLELTSVQPELQ 622

  Fly   120 YEYLDSYDVTLESSEDVACSADELVSIE-----PAISAPEESVYSLSPKPVTFEDEDSGQAA--- 176
            .|.:.:..:...:|..|..:....|.::     |:::.|  :|.:: |.|       :|.||
  Rat   623 LELVPTPGIAAPASATVVVAPPGYVVLQEVMVLPSVATP--TVVAI-PGP-------AGSAALTP 677

  Fly   177 ------------SFTCNICNNVYSERVKLTNHMKVHSAKKPHECEICHKRFRQTPQLARHMNTHT 229
                        ...|..|...:|....|..|...|:.::|:.|..|.|.|.|...|..|...||
  Rat   678 ARQRRKRRVRNRPTVCGECGKGFSRSTDLVRHQATHTGERPYLCSECGKSFSQHSNLVTHQRIHT 742

  Fly   230 GNRPYKCDYCDSRFADPSTRIKHQRIHTNERPYKCEFCSRSFGYSNVLRVHLKTHTGERPFSCQY 294
            |.:||.|.||..||::.|..::|||.||.||||.|..|.:.|..|:.|..|.:||:||||:.|:.
  Rat   743 GEKPYACTYCSKRFSESSALVQHQRTHTGERPYACGDCGKRFSVSSNLLRHRRTHSGERPYVCED 807

  Fly   295 CQKSFSQLHHKNSHEK 310
            |.:.|.|......||:
  Rat   808 CGERFRQKVQIRRHER 823

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4854	NP_650860.1	zf-AD	12..>57	CDD:285071	12/46 (26%)
		C2H2 Zn finger	180..200	CDD:275368	5/19 (26%)
		zf-H2C2_2	193..217	CDD:290200	8/23 (35%)
		COG5048	201..>258	CDD:227381	23/56 (41%)
		C2H2 Zn finger	208..228	CDD:275368	7/19 (37%)
		zf-H2C2_2	221..244	CDD:290200	11/22 (50%)
		C2H2 Zn finger	236..256	CDD:275368	9/19 (47%)
		zf-H2C2_2	251..273	CDD:290200	12/21 (57%)
		C2H2 Zn finger	264..284	CDD:275368	6/19 (32%)
		zf-H2C2_2	277..301	CDD:290200	11/23 (48%)
		C2H2 Zn finger	292..312	CDD:275368	6/19 (32%)
Zfp853	XP_038945781.1	COG5048	<690..805	CDD:227381	46/114 (40%)
		C2H2 Zn finger	693..713	CDD:275368	5/19 (26%)
		C2H2 Zn finger	721..741	CDD:275368	7/19 (37%)
		C2H2 Zn finger	749..769	CDD:275368	9/19 (47%)
		C2H2 Zn finger	777..797	CDD:275368	6/19 (32%)
		C2H2 Zn finger	805..823	CDD:275368	5/17 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910