DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4854 and ZNF891

DIOPT Version :9

Sequence 1:NP_650860.1 Gene:CG4854 / 42391 FlyBaseID:FBgn0038766 Length:319 Species:Drosophila melanogaster
Sequence 2:NP_001264220.1 Gene:ZNF891 / 101060200 HGNCID:38709 Length:544 Species:Homo sapiens


Alignment Length:279 Identity:75/279 - (26%)
Similarity:124/279 - (44%) Gaps:24/279 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly    54 CTSCALLLRAALKLRSLCQQTEKDLKEQKLQEINIEIVHDEQETKKKTESRDLSKNEATGSDSEL 118
            |..|...: ..||..|:.....|:...:||.|     .|:...|....:.....:.|.|.|...:
Human   216 CQKCYSEI-GCLKHNSIINNYVKNSISEKLYE-----SHECDTTLWHFQRNQTVQKEYTYSKHGM 274

  Fly   119 EYEYLDSYDV--TLESSEDVA-CSADELVSIEPAISAPEES-------------VYSLSPKPVTF 167
            .:.: :.:.|  .|..:::.. |:.||.:..:.::....::             .:........:
Human   275 HFTH-NMFPVPNNLHMAQNACECNKDETLCHQSSLKKQGQTHTEKKHECNQCGKAFKRISNLTLY 338

  Fly   168 EDEDSGQAASFTCNICNNVYSERVKLTNHMKVHSAKKPHECEICHKRFRQTPQLARHMNTHTGNR 232
            :....|: ..:.|..|..|:::...|..|::.|:.:||:||..|.|.|.|...|..||.||||.:
Human   339 KKSHMGE-KQYECKECGKVFNDSSTLRRHVRTHTGEKPYECNQCGKAFSQKTSLKAHMRTHTGEK 402

  Fly   233 PYKCDYCDSRFADPSTRIKHQRIHTNERPYKCEFCSRSFGYSNVLRVHLKTHTGERPFSCQYCQK 297
            ||:|:.|...|...|..|.|:||||.|:.|:|..|.::|..|:.|:||.|.||||..:.|..|.|
Human   403 PYECNQCGKSFGTSSYLIVHKRIHTGEKLYECSECGKAFNTSSHLKVHKKIHTGENVYECSDCGK 467

  Fly   298 SFSQLHHKNSHEKSHKRTK 316
            .||.:.....|.::|...|
Human   468 VFSGVSSLRMHIRTHTGEK 486

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4854NP_650860.1 zf-AD 12..>57 CDD:285071 1/2 (50%)
C2H2 Zn finger 180..200 CDD:275368 5/19 (26%)
zf-H2C2_2 193..217 CDD:290200 10/23 (43%)
COG5048 201..>258 CDD:227381 26/56 (46%)
C2H2 Zn finger 208..228 CDD:275368 8/19 (42%)
zf-H2C2_2 221..244 CDD:290200 11/22 (50%)
C2H2 Zn finger 236..256 CDD:275368 7/19 (37%)
zf-H2C2_2 251..273 CDD:290200 10/21 (48%)
C2H2 Zn finger 264..284 CDD:275368 8/19 (42%)
zf-H2C2_2 277..301 CDD:290200 12/23 (52%)
C2H2 Zn finger 292..312 CDD:275368 6/19 (32%)
ZNF891NP_001264220.1 KRAB 43..99 CDD:214630
KRAB 43..82 CDD:279668
COG5048 <272..544 CDD:227381 61/217 (28%)
C2H2 Zn finger 295..315 CDD:275368 3/19 (16%)
C2H2 Zn finger 322..342 CDD:275368 0/19 (0%)
zf-C2H2 348..370 CDD:278523 5/21 (24%)
C2H2 Zn finger 350..370 CDD:275368 5/19 (26%)
zf-H2C2_2 363..387 CDD:290200 10/23 (43%)
C2H2 Zn finger 378..398 CDD:275368 8/19 (42%)
zf-H2C2_2 390..415 CDD:290200 12/24 (50%)
C2H2 Zn finger 406..426 CDD:275368 7/19 (37%)
zf-H2C2_2 418..443 CDD:290200 11/24 (46%)
C2H2 Zn finger 434..454 CDD:275368 8/19 (42%)
zf-H2C2_2 446..470 CDD:290200 11/23 (48%)
C2H2 Zn finger 462..482 CDD:275368 6/19 (32%)
zf-H2C2_2 474..498 CDD:290200 3/13 (23%)
C2H2 Zn finger 490..510 CDD:275368
zf-H2C2_2 502..527 CDD:290200
C2H2 Zn finger 518..538 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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