DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4854 and si:dkey-210j14.3

DIOPT Version :9

Sequence 1:	NP_650860.1	Gene:	CG4854 / 42391	FlyBaseID:	FBgn0038766	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	XP_001342850.3	Gene:	si:dkey-210j14.3 / 100003238	ZFINID:	ZDB-GENE-131121-88	Length:	350	Species:	Danio rerio

Alignment Length:	321	Identity:	86/321 - (26%)
Similarity:	130/321 - (40%)	Gaps:	78/321 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 ALLLRAALKLRSLCQQTEKDLKEQKLQEINIEIVHDEQETKKKTESR------DLSKNEATGS-- 114
            :||||..:   |.|....:.||::      ...:..|.::.:||.::      ..|:...|||
Zfish    36 SLLLRLEI---SRCTNENESLKKK------CHFLESELQSARKTAAKMNGTEAPFSRTGLTGSAR 91

  Fly   115 ----DSELEYEYL--------DSYDVTLESSEDVACSADELVSI-------EP-AISAPEESVYS 159
                |:....|:.        .:.....||.:|.:..|::.||:       || .|...||:...
Zfish    92 RPSIDNAFSKEWCMNLWRHEESNAGEQEESHQDSSGMAEDPVSLLDDEEDEEPDMIMIKEETFDD 156

  Fly   160 LSPKPVTFEDEDSGQAA--------SFTC----------------NI-----------------C 183
            .|.|....|||.|..|.        |..|                |:                 .
Zfish   157 CSGKNKPDEDEMSSLAGPAMPSDGRSQNCEDYITYTVPSDEQARPNVQQPQPEEESLHGTISTHG 221

  Fly   184 NNVYSERVKLTNHMKVHSAKKPHECEICHKRFRQTPQLARHMNTHTGNRPYKCDYCDSRFADPST 248
            :|...:....|::....|.:|..||..|.:.|.:...|..||.||:|.:|:.|..|..|||..:.
Zfish   222 HNTAEQNFPSTHNPTSFSEEKRFECVFCQRTFNKLTYLKAHMRTHSGEKPFVCTVCGKRFAQKTY 286

  Fly   249 RIKHQRIHTNERPYKCEFCSRSFGYSNVLRVHLKTHTGERPFSCQYCQKSFSQLHHKNSHE 309
            ...|||.|:.||||.|..|.:||...:.|.|||::||||:|:||..|.||::.....|:|:
Zfish   287 LRIHQRTHSGERPYSCMECGKSFAQKSSLNVHLRSHTGEKPYSCSECGKSYAYKQGFNTHQ 347

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4854	NP_650860.1	zf-AD	12..>57	CDD:285071
		C2H2 Zn finger	180..200	CDD:275368	4/52 (8%)
		zf-H2C2_2	193..217	CDD:290200	7/23 (30%)
		COG5048	201..>258	CDD:227381	22/56 (39%)
		C2H2 Zn finger	208..228	CDD:275368	6/19 (32%)
		zf-H2C2_2	221..244	CDD:290200	10/22 (45%)
		C2H2 Zn finger	236..256	CDD:275368	8/19 (42%)
		zf-H2C2_2	251..273	CDD:290200	12/21 (57%)
		C2H2 Zn finger	264..284	CDD:275368	8/19 (42%)
		zf-H2C2_2	277..301	CDD:290200	14/23 (61%)
		C2H2 Zn finger	292..312	CDD:275368	6/18 (33%)
si:dkey-210j14.3	XP_001342850.3	COG5048	227..>295	CDD:227381	22/67 (33%)
		C2H2 Zn finger	246..266	CDD:275368	6/19 (32%)
		zf-H2C2_2	258..283	CDD:290200	11/24 (46%)
		C2H2 Zn finger	274..294	CDD:275368	8/19 (42%)
		zf-H2C2_2	286..311	CDD:290200	12/24 (50%)
		C2H2 Zn finger	302..322	CDD:275368	8/19 (42%)
		zf-H2C2_2	314..339	CDD:290200	14/24 (58%)
		C2H2 Zn finger	330..347	CDD:275368	5/16 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910