Protein Alignment CG4424 and ZNF251

DIOPT Version :10

• Sequence 1: NP_650859.3
• Gene: CG4424 / 42390
• FlyBaseID: FBgn0038765
• Length: 345
• Species: Drosophila melanogaster
• Sequence 2: NP_612376.1
• Gene: ZNF251 / 90987
• HGNCID: 13045
• Length: 671
• Species: Homo sapiens
• Alignment Length: 144
• Identity: 60/144 - (41%)
• Similarity: 82/144 - (56%)
• Gaps: 2/144 - (1%)

  Fly   185 KLHVCAICGNGYPRKSTLDTHMRRHNDERPYECEICHKSFHVNYQLKRHIRQHTGAKPYTCQYCQ 249
            |.|.|..||..:.:.|:|..|.|.|..|:||.|..|.::|..|..|..|:|.|||.|||.|..|.
Human   375 KPHKCNQCGKAFSQSSSLFLHHRVHTGEKPYVCNECGRAFGFNSHLTEHVRIHTGEKPYVCNECG 439

  Fly   250 RNFADRTSLVKHERTHRNERPYACKTCGKKFTYASVLKMHYKTHTGEKPHICQLCNKSFARIHNL 314
            :.|...::||:|.|.|..|:||.|..|||.|:.:|.|.:|.:.||||||:.|..|.|:|:|...|
Human   440 KAFRRSSTLVQHRRVHTGEKPYQCVECGKAFSQSSQLTLHQRVHTGEKPYDCGDCGKAFSRRSTL 504

  Fly   315 VAHLQTQQHINDPR 328
            :.|.:.  |..:.|
Human   505 IQHQKV--HSGETR 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4424	NP_650859.3	zf-AD	10..92	CDD:462262
		C2H2 Zn finger	189..209	CDD:275368	7/19 (37%)
		COG5048	210..>345	CDD:227381	50/119 (42%)
		C2H2 Zn finger	217..237	CDD:275368	7/19 (37%)
		C2H2 Zn finger	245..265	CDD:275368	7/19 (37%)
		C2H2 Zn finger	273..293	CDD:275368	8/19 (42%)
		C2H2 Zn finger	301..320	CDD:275368	7/18 (39%)
ZNF251	NP_612376.1	KRAB	15..75	CDD:214630
		C2H2 Zn finger	181..203	CDD:275368
		COG5048	207..635	CDD:227381	60/144 (42%)
		C2H2 Zn finger	211..231	CDD:275368
		C2H2 Zn finger	239..259	CDD:275368
		C2H2 Zn finger	267..287	CDD:275368
		C2H2 Zn finger	295..315	CDD:275368
		C2H2 Zn finger	323..343	CDD:275368
		C2H2 Zn finger	351..371	CDD:275368
		C2H2 Zn finger	379..399	CDD:275368	7/19 (37%)
		C2H2 Zn finger	407..427	CDD:275368	7/19 (37%)
		C2H2 Zn finger	435..455	CDD:275368	7/19 (37%)
		C2H2 Zn finger	463..483	CDD:275368	8/19 (42%)
		C2H2 Zn finger	491..511	CDD:275368	7/21 (33%)
		C2H2 Zn finger	568..588	CDD:275368
		C2H2 Zn finger	596..616	CDD:275368