DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4424 and dati

DIOPT Version :9

Sequence 1:	NP_650859.3	Gene:	CG4424 / 42390	FlyBaseID:	FBgn0038765	Length:	345	Species:	Drosophila melanogaster
Sequence 2:	NP_001245421.1	Gene:	dati / 43789	FlyBaseID:	FBgn0262636	Length:	1150	Species:	Drosophila melanogaster

Alignment Length:	318	Identity:	80/318 - (25%)
Similarity:	116/318 - (36%)	Gaps:	87/318 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    90 REYVIKDAVEQGVVKEVVQQTRPS-----TPPPIETEQLEPPEDEVLEEGVWSTEDPIEETPHGP 149
            |..:|.......|..:..|.:.||     |...::|.|.:|     :..|.      :..:..|.
  Fly   269 RALIIGLGAPSTVSTDDAQSSAPSHQLAGTGRALQTHQCKP-----MSPGT------VGSSNLGA 322

  Fly   150 AEKERPTVLTVEMLPAPYPPPASTPP--------------------------PAPAGAVKGK-LH 187
            ..:..||.::.........|..||.|                          .:.|.|:..: |.
  Fly   323 GRRSAPTTISKTFSQGQQSPQHSTTPSGGSTTPDIKYNNDKMANEIQLQLSRSSSAAAISERTLE 387

  Fly   188 VC------------------------AICGNGYPRKSTLDTHMRRHNDERPYECEICHKSFHVNY 228
            .|                        .:..:|....:.|...:...:|.:|::|:.|.|||..|:
  Fly   388 ECWSTLQRLFMHKSAMQQIQQQIPRVGLGTHGVTGSANLGGSITPSSDTKPHQCQQCMKSFSSNH 452

  Fly   229 QLKRHIRQHTGAKPYTCQYCQRNFADRTSLVKHERTHRNERPYAC--KTCGKKFTYASVLKMHYK 291
            ||.:|||.|||.|||.|.||.|.|...:.:.:|.|.|..||||.|  ..||:.|...|.|:.|.:
  Fly   453 QLVQHIRVHTGEKPYKCSYCDRRFKQLSHVQQHTRLHTGERPYKCHLPDCGRAFIQLSNLQQHLR 517

  Fly   292 THTGE------KPHICQLCNKSFA-----RIH---NLVAHLQT-QQH---INDPRLTA 331
            .|..:      :|..|.:|.|.||     |.|   .|..||.. |||   |..|..|:
  Fly   518 NHDAQVERAKNRPFHCNICGKGFATESSLRTHTSKELQLHLGVLQQHAALIGGPNATS 575

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4424	NP_650859.3	zf-AD	10..92	CDD:285071	1/1 (100%)
		C2H2 Zn finger	189..209	CDD:275368	3/43 (7%)
		DUF45	<204..281	CDD:302795	34/78 (44%)
		COG5048	210..>345	CDD:227381	56/142 (39%)
		C2H2 Zn finger	217..237	CDD:275368	11/19 (58%)
		C2H2 Zn finger	245..265	CDD:275368	7/19 (37%)
		zf-H2C2_2	257..282	CDD:290200	11/26 (42%)
		C2H2 Zn finger	273..293	CDD:275368	7/21 (33%)
		zf-H2C2_2	286..310	CDD:290200	9/34 (26%)
		C2H2 Zn finger	301..320	CDD:275368	10/26 (38%)
dati	NP_001245421.1	COG5048	<429..>511	CDD:227381	35/81 (43%)
		C2H2 Zn finger	441..461	CDD:275368	11/19 (58%)
		zf-H2C2_2	454..478	CDD:290200	15/23 (65%)
		C2H2 Zn finger	469..489	CDD:275368	7/19 (37%)
		zf-H2C2_2	481..508	CDD:290200	11/26 (42%)
		C2H2 Zn finger	497..519	CDD:275368	7/21 (33%)
		C2H2 Zn finger	533..557	CDD:275368	8/23 (35%)
		C2H2 Zn finger	576..594	CDD:275368	80/318 (25%)
		C2H2 Zn finger	667..687	CDD:275370
		C2H2 Zn finger	702..719	CDD:275370
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100