Protein Alignment CG4424 and trem

DIOPT Version :10

• Sequence 1: NP_650859.3
• Gene: CG4424 / 42390
• FlyBaseID: FBgn0038765
• Length: 345
• Species: Drosophila melanogaster
• Sequence 2: NP_650861.1
• Gene: trem / 42392
• FlyBaseID: FBgn0038767
• Length: 439
• Species: Drosophila melanogaster
• Alignment Length: 423
• Identity: 124/423 - (29%)
• Similarity: 179/423 - (42%)
• Gaps: 124/423 - (29%)

  Fly    10 LCRTCL---QDGEAHMVSIF-QTADDRLPGGVSLCDKIESLSGIQIRATAKEEVLPTRICLRCKA 70
            :||.||   .:||..:..|| :||..||...:.:|      :||.:   :.::..|.::|.:|..
  Fly    11 VCRVCLNNPSEGEELLHDIFSETASTRLDQMLHIC------AGIPV---SLDDNFPDKMCSKCVR 66

  Fly    71 FLTLAHKFRQICQRSNEFLRE-------------------------------------------- 91
            .|.|.:|||..||||::.:.:
  Fly    67 CLRLCYKFRLTCQRSHQHIMDMLDREASNANAAGEGDLLSIAEDLSVESVLKSWEDYASQLDGGM 131

  Fly    92 --------------YVIKDA------------VEQGVVKEV----------------------VQ 108
                          ||::|.            ..|.|..|:                      :.
  Fly   132 KVEGEEDQQHQVITYVVEDGDTDDTNMFDVHDPTQPVPNEIEEAETYAEYEEYELLTNENSPEIA 196

  Fly   109 QTRPSTPPPIETEQLEPPEDEVLEEGVWSTEDPIEETPHGPAEK-ERPTVLTVEMLPAPY---PP 169
            |.:.||...:.||  ||||:|:.|:.:.|.||  .:..|...|| :|.     ...|..|   .|
  Fly   197 QEKGSTGTDVATE--EPPEEEIAEDILDSDED--YDPTHAKPEKCDRS-----GRKPVAYHKNSP 252

  Fly   170 PASTPPPAPAGAVKGKL--HVCAICGNGYPRKSTLDTHMRRHNDERPYECEICHKSFHVNYQLKR 232
            ...|.........:.||  ::|.:|||.||.::.|..||:.|:..:|:|||||.:.|..|.||.|
  Fly   253 KVETFKKKVGRKPRNKLSTYICDVCGNIYPTQARLTEHMKFHSGVKPHECEICGRGFVQNQQLVR 317

  Fly   233 HIRQHTGAKPYTCQYCQRNFADRTSLVKHERTHRNERPYACKTCGKKFTYASVLKMHYKTHTGEK 297
            |:..|||.:||.|.||...||||::..||.|.|..||||.|..|.:.|||:..||.|...|||||
  Fly   318 HMNTHTGNRPYKCNYCPAAFADRSTKTKHHRIHTKERPYVCDVCSRTFTYSDNLKFHKMIHTGEK 382

  Fly   298 PHICQLCNKSFARIHNLVAHLQTQQHINDPRLT 330
            ||:|.||.|.|.:.:.|..|.:|    ::.|:|
  Fly   383 PHVCDLCGKGFVKAYKLRLHRET----HNRRIT 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4424	NP_650859.3	zf-AD	10..92	CDD:462262	27/143 (19%)
		C2H2 Zn finger	189..209	CDD:275368	9/19 (47%)
		COG5048	210..>345	CDD:227381	57/121 (47%)
		C2H2 Zn finger	217..237	CDD:275368	10/19 (53%)
		C2H2 Zn finger	245..265	CDD:275368	10/19 (53%)
		C2H2 Zn finger	273..293	CDD:275368	8/19 (42%)
		C2H2 Zn finger	301..320	CDD:275368	7/18 (39%)
trem	NP_650861.1	zf-AD	11..87	CDD:214871	27/84 (32%)
		COG5048	<264..411	CDD:227381	68/150 (45%)
		C2H2 Zn finger	274..294	CDD:275368	9/19 (47%)
		C2H2 Zn finger	302..322	CDD:275368	10/19 (53%)
		C2H2 Zn finger	330..350	CDD:275368	10/19 (53%)
		C2H2 Zn finger	358..378	CDD:275368	8/19 (42%)
		C2H2 Zn finger	386..406	CDD:275368	8/23 (35%)