DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4424 and CG6654

DIOPT Version :9

Sequence 1:NP_650859.3 Gene:CG4424 / 42390 FlyBaseID:FBgn0038765 Length:345 Species:Drosophila melanogaster
Sequence 2:NP_650429.1 Gene:CG6654 / 41831 FlyBaseID:FBgn0038301 Length:639 Species:Drosophila melanogaster


Alignment Length:583 Identity:124/583 - (21%)
Similarity:171/583 - (29%) Gaps:283/583 - (48%)


- Green bases have known domain annotations that are detailed below.


  Fly    10 LCRTCLQDGEAHMVSIFQTADDRLPGGVSLC--DKIESLSGIQIRATAKEEVLPTRICLRCKAFL 72
            :|.||| .....::||:.       ||...|  |.|...:..:.|   :.:.||.::||.|.:.:
  Fly     6 ICLTCL-SSTGPLLSIYD-------GGSGSCLADMIREFTKTKPR---RNDNLPEKVCLSCLSEI 59

  Fly    73 TLAHKFRQICQRSNEFLREY---------------------------------------VIKDAV 98
            :..:.|:..|:.|:..||:.                                       |..|||
  Fly    60 SNCYTFKIKCENSSRTLRQLLPNALPEEPDSKVSISCPVATTDQAVQTTSWEPDRCTASVQTDAV 124

  Fly    99 -----EQ--GVVK-------------EVVQQTRPSTPPP---------------------IETEQ 122
                 ||  .::|             ||.....|..|..                     .:|..
  Fly   125 TTTDAEQNTSLIKSTISVDLDYEGEGEVFDYELPDEPVEKTTSLILQVQGNLKDEKEVVFTQTNV 189

  Fly   123 LEPPEDEVLE-----------EGV------------------------WSTEDPIEETPHGPAEK 152
            :...:|..||           |||                        ...|:...:||.|..|:
  Fly   190 IYEGDDHELEQQIRECNLAIFEGVDNEAEIITVTAPQVTTRKSAAKLLTQQENDKHQTPVGSKEE 254

  Fly   153 ERPTVLTVEMLP----------------APYPPPASTPP-------------PAP-AGAVKGK-- 185
            .|.  |..|.:|                .|..||:...|             .|| ||.|.|.  
  Fly   255 ARE--LEKEQVPQSAKRTSRRRGVVKQDVPATPPSDAEPSPKQHRLGTQRKLSAPRAGTVNGPST 317

  Fly   186 ----------------------------------------------------------------L 186
                                                                            .
  Fly   318 TSGAATTPELKYHCDRCNAGFAVEKSLMIHRRQKGCINRNYKCNECEKVFVSPDHLAEHQASHGA 382

  Fly   187 HVCAICG--------------NGYPRK---------------STLDTHMRRHNDERPYECEICHK 222
            |.|..||              .|:.|.               |||..|||.|..|:|:.|.||.|
  Fly   383 HNCPECGIRCDSKEALSKHMVQGHKRNLRNQCNICQKVFTMLSTLRDHMRIHTGEKPFVCNICGK 447

  Fly   223 SFHVNYQLKR----------------------------HIRQHTGAKPYTCQYCQRNFADRTSLV 259
            ||..|..|::                            |.|.|||.||:.|:.|...|....||.
  Fly   448 SFTQNANLRQHKLRHSETKSFKCELCPHSFVTKAELTSHARTHTGDKPFECEVCLARFTTSCSLA 512

  Fly   260 KHERTHRNERPYACKTCGKKFTYASVLKMHYKTHTGEKPHICQLCNKSFARIHNLVAHLQTQQ 322
            ||:|.|..||||||..|..:||..:|||.|.:|||||:|::|..|:|:|.:..:...|.:|.|
  Fly   513 KHKRKHTGERPYACDLCPMRFTALNVLKNHRRTHTGERPYVCPFCSKTFTQRGDCQMHQRTHQ 575

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4424NP_650859.3 zf-AD 10..92 CDD:285071 22/83 (27%)
C2H2 Zn finger 189..209 CDD:275368 11/48 (23%)
DUF45 <204..281 CDD:302795 37/104 (36%)
COG5048 210..>345 CDD:227381 52/141 (37%)
C2H2 Zn finger 217..237 CDD:275368 10/47 (21%)
C2H2 Zn finger 245..265 CDD:275368 8/19 (42%)
zf-H2C2_2 257..282 CDD:290200 14/24 (58%)
C2H2 Zn finger 273..293 CDD:275368 8/19 (42%)
zf-H2C2_2 286..310 CDD:290200 13/23 (57%)
C2H2 Zn finger 301..320 CDD:275368 5/18 (28%)
CG6654NP_650429.1 zf-AD 6..79 CDD:285071 22/83 (27%)
C2H2 Zn finger 331..354 CDD:275368 0/22 (0%)
COG5048 <357..570 CDD:227381 62/212 (29%)
C2H2 Zn finger 360..380 CDD:275368 0/19 (0%)
C2H2 Zn finger 385..406 CDD:275370 3/20 (15%)
C2H2 Zn finger 414..434 CDD:275368 6/19 (32%)
zf-H2C2_2 427..451 CDD:290200 13/23 (57%)
C2H2 Zn finger 442..490 CDD:275368 10/47 (21%)
C2H2 Zn finger 470..487 CDD:275368 0/16 (0%)
zf-H2C2_2 482..507 CDD:290200 10/24 (42%)
C2H2 Zn finger 498..518 CDD:275368 8/19 (42%)
zf-H2C2_2 510..534 CDD:290200 13/23 (57%)
C2H2 Zn finger 526..546 CDD:275368 8/19 (42%)
zf-H2C2_2 539..563 CDD:290200 13/23 (57%)
C2H2 Zn finger 554..574 CDD:275368 5/19 (26%)
C2H2 Zn finger 582..602 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 84 1.000 Inparanoid score I1804
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.960

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