DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4424 and CG7987

DIOPT Version :9

Sequence 1:	NP_650859.3	Gene:	CG4424 / 42390	FlyBaseID:	FBgn0038765	Length:	345	Species:	Drosophila melanogaster
Sequence 2:	NP_650375.1	Gene:	CG7987 / 41768	FlyBaseID:	FBgn0038244	Length:	1283	Species:	Drosophila melanogaster

Alignment Length:	163	Identity:	53/163 - (32%)
Similarity:	80/163 - (49%)	Gaps:	17/163 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   183 KGKLHVCAICGNGYPRKSTLDTHMRRHNDERP---YECEICHKSFHVNYQLKRHIRQHTGAKPYT 244
            :.|..||.:|...:|...||..|...|:...|   :.|..|.|:|......:.|:|.|||.:||.
  Fly   583 RDKSVVCEVCQEEFPDGRTLSNHRHSHSTTTPGKLFPCLECGKTFGSRSSQQIHVRIHTGERPYG 647

  Fly   245 CQYCQRNFADRTSLVKHERTHRNERPYACKTCGKKFTYASVLKMHYKTH-----TGEKPHICQLC 304
            |:||.:.|||..:|.||||.|..|:||||..|.:.|....||:.|.::|     .....:.|.:|
  Fly   648 CRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDVARNTYHCTVC 712

  Fly   305 NKSFARIHNLVAHL---------QTQQHINDPR 328
            ::..|..::|:.||         :.:|.:..||
  Fly   713 SEDLASSNDLIQHLIQHSDSNTAKQRQPVTGPR 745

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4424	NP_650859.3	zf-AD	10..92	CDD:285071
		C2H2 Zn finger	189..209	CDD:275368	6/19 (32%)
		DUF45	<204..281	CDD:302795	32/79 (41%)
		COG5048	210..>345	CDD:227381	44/136 (32%)
		C2H2 Zn finger	217..237	CDD:275368	6/19 (32%)
		C2H2 Zn finger	245..265	CDD:275368	11/19 (58%)
		zf-H2C2_2	257..282	CDD:290200	13/24 (54%)
		C2H2 Zn finger	273..293	CDD:275368	6/19 (32%)
		zf-H2C2_2	286..310	CDD:290200	5/28 (18%)
		C2H2 Zn finger	301..320	CDD:275368	6/27 (22%)
CG7987	NP_650375.1	C2H2 Zn finger	142..162	CDD:275368
		C2H2 Zn finger	170..186	CDD:275368
		COG5048	326..734	CDD:227381	50/150 (33%)
		C2H2 Zn finger	343..363	CDD:275368
		C2H2 Zn finger	371..391	CDD:275368
		C2H2 Zn finger	424..444	CDD:275368
		C2H2 Zn finger	476..496	CDD:275368
		C2H2 Zn finger	504..523	CDD:275368
		C2H2 Zn finger	534..554	CDD:275370
		C2H2 Zn finger	562..582	CDD:275370
		C2H2 Zn finger	589..609	CDD:275368	6/19 (32%)
		C2H2 Zn finger	620..640	CDD:275368	6/19 (32%)
		C2H2 Zn finger	648..668	CDD:275368	11/19 (58%)
		zf-H2C2_2	661..685	CDD:290200	13/23 (57%)
		C2H2 Zn finger	676..696	CDD:275368	6/19 (32%)
		C2H2 Zn finger	709..726	CDD:275371	4/16 (25%)
		Hph	921..>1017	CDD:290417
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100