DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4424 and CG5245

DIOPT Version :9

Sequence 1:	NP_650859.3	Gene:	CG4424 / 42390	FlyBaseID:	FBgn0038765	Length:	345	Species:	Drosophila melanogaster
Sequence 2:	NP_650197.1	Gene:	CG5245 / 41530	FlyBaseID:	FBgn0038047	Length:	501	Species:	Drosophila melanogaster

Alignment Length:	235	Identity:	68/235 - (28%)
Similarity:	103/235 - (43%)	Gaps:	36/235 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   124 EPPEDEVLEEG-VWSTEDPIEETPHGPAEKERPTVLTVEMLPAPYPPPASTPPPAPAGAVKGKLH 187
            |||:::..||. ::.:....||     .|.|    :.:|.. ..|.....     |...|..||.
  Fly    14 EPPQEDTFEEELIFISNSDFEE-----LESE----IKIENF-CSYGKDLE-----PVKGVPSKLK 63

  Fly   188 V-------------------CAICGNGYPRKSTLDTHMRRHNDERPYECEICHKSFHVNYQLKRH 233
            .                   |..|...:.||..|::|:|.|.:|||:||..|.|||......|||
  Fly    64 TCKSKIAKKRPLRKQTDTFKCTQCQKTFTRKENLESHLRLHAEERPFECSHCSKSFGRRTHYKRH 128

  Fly   234 IRQHTGAKPYTCQYCQRNFADRTSLVKHERTHRNERPYACKTCGKKFTYASVLKMHYKTHTGEKP 298
            :.:|. .:|:.|.:|.:.|...:||.:|...|..|||:.|..|...|...|.|::|.:||:.|:|
  Fly   129 LLKHE-KRPHKCSHCSKTFTQNSSLKQHLHEHTGERPFKCTQCSTSFARKSHLQVHLRTHSEERP 192

  Fly   299 HICQLCNKSFARIHNLVAHLQTQQHINDPRLTAYLSTFKV 338
            ..|..|.|:|....:|..||:|.|.....:.:....:||:
  Fly   193 FECTHCEKAFKNNSHLQEHLRTHQEARPFKCSHCSKSFKL 232

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4424	NP_650859.3	zf-AD	10..92	CDD:285071
		C2H2 Zn finger	189..209	CDD:275368	7/19 (37%)
		DUF45	<204..281	CDD:302795	29/76 (38%)
		COG5048	210..>345	CDD:227381	45/129 (35%)
		C2H2 Zn finger	217..237	CDD:275368	8/19 (42%)
		C2H2 Zn finger	245..265	CDD:275368	6/19 (32%)
		zf-H2C2_2	257..282	CDD:290200	10/24 (42%)
		C2H2 Zn finger	273..293	CDD:275368	6/19 (32%)
		zf-H2C2_2	286..310	CDD:290200	10/23 (43%)
		C2H2 Zn finger	301..320	CDD:275368	7/18 (39%)
CG5245	NP_650197.1	COG5048	74..478	CDD:227381	53/160 (33%)
		C2H2 Zn finger	84..104	CDD:275368	7/19 (37%)
		C2H2 Zn finger	112..132	CDD:275368	8/19 (42%)
		C2H2 Zn finger	139..159	CDD:275368	6/19 (32%)
		C2H2 Zn finger	167..187	CDD:275368	6/19 (32%)
		zf-H2C2_2	179..204	CDD:290200	10/24 (42%)
		C2H2 Zn finger	195..215	CDD:275368	7/19 (37%)
		C2H2 Zn finger	223..243	CDD:275368	2/10 (20%)
		C2H2 Zn finger	250..270	CDD:275368
		C2H2 Zn finger	278..298	CDD:275368
		C2H2 Zn finger	306..326	CDD:275368
		C2H2 Zn finger	334..354	CDD:275368
		C2H2 Zn finger	362..382	CDD:275368
		C2H2 Zn finger	390..410	CDD:275368
		C2H2 Zn finger	418..438	CDD:275368
		C2H2 Zn finger	446..466	CDD:275368
		C2H2 Zn finger	474..492	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471458
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930