DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4424 and CG6813

DIOPT Version :9

Sequence 1:	NP_650859.3	Gene:	CG4424 / 42390	FlyBaseID:	FBgn0038765	Length:	345	Species:	Drosophila melanogaster
Sequence 2:	NP_001163590.1	Gene:	CG6813 / 41396	FlyBaseID:	FBgn0037923	Length:	294	Species:	Drosophila melanogaster

Alignment Length:	318	Identity:	93/318 - (29%)
Similarity:	135/318 - (42%)	Gaps:	48/318 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 CRTCLQDGEAHMVSIFQTADDRLPGGVSLCDKIESLSGIQIRATAKEEVLPTRICLRCKAFLTLA 75
            ||.|.:....  :.:|.      ||...|..:|.|::|:::  :.|:|: ..::|..|...|..|
  Fly     6 CRICSRSDAP--IDLFG------PGNGHLVRQIHSITGVEL--SCKKEI-SGQMCTTCLDNLQAA 59

  Fly    76 HKFRQIC---QRSNEFLREYVIKDAVEQGVVKEVVQQTRPSTPPPIETEQLEPPEDEVLEEGVWS 137
            .||||.|   ::.|....|...||.....::.|.:...:      ||:|         |:|.:..
  Fly    60 IKFRQRCIIAEKQNLERIECDSKDCSTDPIIYEDIDDNQ------IESE---------LDESILC 109

  Fly   138 TEDPIEETPHGPAEKERPTVLTVEMLPAPYPPPASTPPPAPAGAVKGKLHVCAICGNGYPRKSTL 202
            .|  :::.|...|||              ...|.|.......|...|. :||..||.....||..
  Fly   110 PE--VKDLPMPSAEK--------------VSAPTSLNHQKSIGGGTGP-YVCPDCGRIINNKSNF 157

  Fly   203 DTHMRRHNDERPYECEI--CHKSFHVNYQLKRHIRQHTGAKPYTCQYCQRNFADRTSLVKHERTH 265
            ..|..||...:.:.|..  |.:||....:|..|.|.|||.:||.|.||.|.|:...:..:|.|.|
  Fly   158 QEHTLRHTGIKNFHCVFLNCERSFATRKELTSHTRIHTGEQPYVCVYCPRRFSSSGARQEHHRRH 222

  Fly   266 RNERPYACKTCGKKFTYASVLKMHYKTHTGEKPHICQLCNKSFARIHNLVAHLQTQQH 323
            ||||.|.|.||.|.|..:..|:.|...|...:.|.|.:|.|.|.||.:|:.||.:..|
  Fly   223 RNERRYECDTCKKSFVSSGCLRKHKMIHVDARNHYCYVCQKHFKRISHLMTHLSSNIH 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4424	NP_650859.3	zf-AD	10..92	CDD:285071	22/83 (27%)
		C2H2 Zn finger	189..209	CDD:275368	6/19 (32%)
		DUF45	<204..281	CDD:302795	32/78 (41%)
		COG5048	210..>345	CDD:227381	44/116 (38%)
		C2H2 Zn finger	217..237	CDD:275368	7/21 (33%)
		C2H2 Zn finger	245..265	CDD:275368	7/19 (37%)
		zf-H2C2_2	257..282	CDD:290200	13/24 (54%)
		C2H2 Zn finger	273..293	CDD:275368	7/19 (37%)
		zf-H2C2_2	286..310	CDD:290200	8/23 (35%)
		C2H2 Zn finger	301..320	CDD:275368	9/18 (50%)
CG6813	NP_001163590.1	zf-AD	6..76	CDD:285071	22/80 (28%)
		C2H2 Zn finger	144..164	CDD:275368	6/19 (32%)
		C2H2 Zn finger	172..194	CDD:275368	7/21 (33%)
		zf-H2C2_2	186..211	CDD:290200	13/24 (54%)
		UFD2	<256..>294	CDD:227443	11/25 (44%)
		C2H2 Zn finger	258..280	CDD:275368	9/21 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG26482
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.970