DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4424 and CG4820

DIOPT Version :9

Sequence 1:	NP_650859.3	Gene:	CG4424 / 42390	FlyBaseID:	FBgn0038765	Length:	345	Species:	Drosophila melanogaster
Sequence 2:	NP_001097748.1	Gene:	CG4820 / 41344	FlyBaseID:	FBgn0037876	Length:	362	Species:	Drosophila melanogaster

Alignment Length:	383	Identity:	91/383 - (23%)
Similarity:	145/383 - (37%)	Gaps:	95/383 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 MMTLCRTCLQDGEAHMVSIFQTADDRL----PGGVSLCDKIESLSGIQIRATAKEEVLPTRICLR 67
            |...||||   |:.      ..||:.|    |.|..|...:.|::...::   ..:.||..||..
  Fly     1 MKEFCRTC---GKT------VVADECLQIFTPAGRKLLQCVRSITNCWLQ---NVQDLPNHICTD 53

  Fly    68 CKAFLTLAHKFRQICQRSNE-FLREYVIKDAVEQGVVKEVVQQTRPSTPPPIETEQLEPPEDEVL 131
            |:..|:...|||:.|.:..: |.|.....:..|.....|.::..:.:.|.|:..::|....|..:
  Fly    54 CQVLLSQVQKFRRRCAKIEKYFARRRRRMNLGEAPAAMEQLRVQQAAAPDPLGIDELMSASDIKI 118

  Fly   132 EEGVWSTEDPI----EETPHGP-AEKERPTVLTV------EMLPAP-------YPPPASTPPPAP 178
            |        ||    ||.|..| .|.:....|:.      ::||.|       .....:|..||.
  Fly   119 E--------PIQLQMEEDPQAPYPENQLEQALSYGNAPGEDILPLPEDYGEAQTEVATTTNEPAQ 175

  Fly   179 -----AGAVKGKLH---------------------------------VCAICGNGYPRKSTLDTH 205
                 ...:|.|.|                                 :|..||..:...|.|..|
  Fly   176 RRSKNTAKIKSKKHTMRVGRKLIHVKVIDDKQPKRIVDRNGPSAKPCICEHCGRQFKDTSNLHVH 240

  Fly   206 MRRHNDERPYECEICHKSFHVNYQLKRHIRQHTGAKPYTCQYCQRNFADRTSLVKHERTHRNERP 270
            :.||...:|:||:.||:..:..:.|:||..:||.. ||.|.:|...::..:|.|:|||.
  Fly   241 LLRHTGTKPFECDQCHQKCYTLHLLRRHQLKHTEG-PYACTFCGLEYSTNSSRVRHERE------ 298

  Fly   271 YACKTCGKKFTYASVLKMHYKTHTGEKPHICQLCNKSFARIHNLVAHLQTQQHINDPR 328
             |||......:...::|      .||:...|::|:..|.|..|...|:.:..||.:.|
  Fly   299 -ACKKGRAPQSKWEIIK------KGERTFHCEVCDLWFLRAGNFTQHINSSSHIENER 349

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4424	NP_650859.3	zf-AD	10..92	CDD:285071	24/86 (28%)
		C2H2 Zn finger	189..209	CDD:275368	6/19 (32%)
		DUF45	<204..281	CDD:302795	25/76 (33%)
		COG5048	210..>345	CDD:227381	34/119 (29%)
		C2H2 Zn finger	217..237	CDD:275368	6/19 (32%)
		C2H2 Zn finger	245..265	CDD:275368	7/19 (37%)
		zf-H2C2_2	257..282	CDD:290200	8/24 (33%)
		C2H2 Zn finger	273..293	CDD:275368	3/19 (16%)
		zf-H2C2_2	286..310	CDD:290200	6/23 (26%)
		C2H2 Zn finger	301..320	CDD:275368	6/18 (33%)
CG4820	NP_001097748.1	zf-AD	4..75	CDD:285071	22/82 (27%)
		C2H2 Zn finger	224..244	CDD:275368	6/19 (32%)
		C2H2 Zn finger	252..272	CDD:275368	6/19 (32%)
		C2H2 Zn finger	279..297	CDD:275368	5/17 (29%)
		C2H2 Zn finger	322..339	CDD:275368	5/16 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.960