DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4424 and CG8478

DIOPT Version :9

Sequence 1:	NP_650859.3	Gene:	CG4424 / 42390	FlyBaseID:	FBgn0038765	Length:	345	Species:	Drosophila melanogaster
Sequence 2:	NP_001163576.1	Gene:	CG8478 / 41194	FlyBaseID:	FBgn0037746	Length:	576	Species:	Drosophila melanogaster

Alignment Length:	207	Identity:	46/207 - (22%)
Similarity:	71/207 - (34%)	Gaps:	62/207 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   171 ASTPPPAPAGAVKGKLHVCAICGNGYPRKSTLDTHMRRHN------------DERPY-------E 216
            ||.|......::..|:..|..|...:..||.||.|||.|:            :..|.       .
  Fly   361 ASKPAKTSTKSIPEKVFSCKNCSTTFRVKSLLDVHMRMHDPVDNGANTLKRLNSNPVAAGVSKNR 425

  Fly   217 CEICHKSFHVNYQLKRHIRQHTGAKPYT----CQYCQRNFADR--------TSLVKHERT----- 264
            |:.|.|:|.:...|..|:.|:....|.:    .::.:.|...:        ||.:.|..|
  Fly   426 CKFCDKNFALERALHIHLMQNCDKIPPSEKRKLEFTELNHEKKAQLPKIGGTSGINHPMTMPQKP 490

  Fly   265 ---------------HRNERPYACKTCGKKFTYASVLKMHYKTHTGEKPHICQLCNKSFARI--- 311
                           .::..|.:.|...|...:|.|    |:|.|...|  |.:|.:||..|
  Fly   491 QQRISTIPKLAPSQGTQSMAPPSVKKIPKNVAHAGV----YRTPTKTVP--CHICKQSFRSILEF 549

  Fly   312 --HNLVAHLQTQ 321
              |:|..|...|
  Fly   550 TNHSLTVHGNNQ 561

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4424	NP_650859.3	zf-AD	10..92	CDD:285071
		C2H2 Zn finger	189..209	CDD:275368	9/19 (47%)
		DUF45	<204..281	CDD:302795	21/127 (17%)
		COG5048	210..>345	CDD:227381	32/168 (19%)
		C2H2 Zn finger	217..237	CDD:275368	6/19 (32%)
		C2H2 Zn finger	245..265	CDD:275368	5/47 (11%)
		zf-H2C2_2	257..282	CDD:290200	6/44 (14%)
		C2H2 Zn finger	273..293	CDD:275368	5/19 (26%)
		zf-H2C2_2	286..310	CDD:290200	8/23 (35%)
		C2H2 Zn finger	301..320	CDD:275368	8/23 (35%)
CG8478	NP_001163576.1	zf-C2H2	377..399	CDD:278523	9/21 (43%)
		C2H2 Zn finger	379..399	CDD:275368	9/19 (47%)
		C2H2 Zn finger	426..444	CDD:275368	6/17 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100