DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4424 and ouib

DIOPT Version :9

Sequence 1:	NP_650859.3	Gene:	CG4424 / 42390	FlyBaseID:	FBgn0038765	Length:	345	Species:	Drosophila melanogaster
Sequence 2:	NP_649822.2	Gene:	ouib / 41039	FlyBaseID:	FBgn0037618	Length:	312	Species:	Drosophila melanogaster

Alignment Length:	346	Identity:	97/346 - (28%)
Similarity:	166/346 - (47%)	Gaps:	65/346 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LNMMTLCRTCLQDGEAHMVSIFQTADDRLPGGVSLCDK---------------IESLSGIQIRAT 54
            ||:  :||.|                    |...:|:|               :..:||:::
  Fly     2 LNI--VCRVC--------------------GRQKICEKSLNLFDLVNRKYLKHLHMISGLRL--- 41

  Fly    55 AKEEVLPTRICLRCKAFLTLAHKFRQICQRSNEFLREYVIKDAVEQGVVKEVVQQTRPSTPPPIE 119
            ...:.:|..:||.|:|.|..|..||::|.::.  .:...|:|....|     .:.|..::  .:|
  Fly    42 VDLDDVPGFMCLCCQAELRSALAFRKLCIKTQ--TKWLTIEDDSSSG-----DEDTNDNS--ELE 97

  Fly   120 TEQL------EPPEDEVLEE--GVWSTEDPIEETPHGPAEKE-RPTVLTVEMLPAPYPPPASTPP 175
            :|:.      :..|.|::||  .|...|:|:::|.:..|:.: |...:..:.:|:......||
  Fly    98 SEKCAFSDFGKKKEGELVEETFQVLIEEEPMDKTLNRDAKAQLREDGIDEKCVPSQKIIKVST-- 160

  Fly   176 PAPAGAVKGKLHVCAICGNGYPRKSTLDTHMRRHNDERPYECEICHKSFHVNYQLKRHIRQHTGA 240
                 .:..::::|.:||.....|.|...|||:|..|||:.|:.|...|....:|:.|.|.|||.
  Fly   161 -----KLDDQIYICELCGTHATSKPTFQRHMRKHRGERPFGCKDCDARFLSAGELRAHHRVHTGE 220

  Fly   241 KPYTCQYCQRNFADRTSLVKHERTHRNERPYACKTCGKKFTYASVLKMHYKTHTGEKPHICQLCN 305
            :|:.|::|::.:......:.|||||.|:|||.|:.||||||.|.|||.|...||||:...|.:|:
  Fly   221 QPFACRFCEKRYVSYMGRLIHERTHTNDRPYVCEECGKKFTTAYVLKNHMVIHTGERNFRCDICD 285

  Fly   306 KSFARIHNLVAHLQTQQHIND 326
            :||.|..:||.|.::..|:.:
  Fly   286 RSFQRKAHLVTHTRSMMHLQN 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4424	NP_650859.3	zf-AD	10..92	CDD:285071	18/96 (19%)
		C2H2 Zn finger	189..209	CDD:275368	8/19 (42%)
		DUF45	<204..281	CDD:302795	33/76 (43%)
		COG5048	210..>345	CDD:227381	49/117 (42%)
		C2H2 Zn finger	217..237	CDD:275368	6/19 (32%)
		C2H2 Zn finger	245..265	CDD:275368	5/19 (26%)
		zf-H2C2_2	257..282	CDD:290200	15/24 (63%)
		C2H2 Zn finger	273..293	CDD:275368	12/19 (63%)
		zf-H2C2_2	286..310	CDD:290200	11/23 (48%)
		C2H2 Zn finger	301..320	CDD:275368	8/18 (44%)
ouib	NP_649822.2	zf-AD	5..78	CDD:214871	18/97 (19%)
		COG5048	<158..300	CDD:227381	59/148 (40%)
		C2H2 Zn finger	169..189	CDD:275368	8/19 (42%)
		C2H2 Zn finger	197..217	CDD:275368	6/19 (32%)
		zf-H2C2_2	209..234	CDD:290200	9/24 (38%)
		C2H2 Zn finger	225..245	CDD:275368	5/19 (26%)
		zf-H2C2_2	241..262	CDD:290200	15/20 (75%)
		C2H2 Zn finger	253..273	CDD:275368	12/19 (63%)
		zf-H2C2_2	266..288	CDD:290200	9/21 (43%)
		C2H2 Zn finger	281..299	CDD:275368	8/17 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.960