DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4424 and nom

DIOPT Version :9

Sequence 1:	NP_650859.3	Gene:	CG4424 / 42390	FlyBaseID:	FBgn0038765	Length:	345	Species:	Drosophila melanogaster
Sequence 2:	NP_001262384.1	Gene:	nom / 41038	FlyBaseID:	FBgn0037617	Length:	370	Species:	Drosophila melanogaster

Alignment Length:	368	Identity:	90/368 - (24%)
Similarity:	145/368 - (39%)	Gaps:	101/368 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 MMTLCRTCLQDGEAHM----VSIFQTADDRLPGGVSLCDKIESLSGIQIRATAKEEVLPTRICLR 67
            ::.:||.|   |.:.:    |.:|:      ||...:..:|:.::||.::....   .|..:|..
  Fly     2 LINVCRVC---GRSRLCPKAVELFK------PGRQDILRRIQLITGILLQQIPN---APDMVCFC 54

  Fly    68 CKAFLTLAHKFRQICQRSNEFLREYVIKDAVEQGVVKEVVQQTRPSTPPPIETEQLEPPEDEVLE 132
            |:..|..|..||:.|                       ::||.:  ..|.::::::...|::.:|
  Fly    55 CQTDLQSAMIFRRQC-----------------------ILQQKK--WVPLLQSDKVGASEEKKVE 94

  Fly   133 EGVWSTEDPIEETPHGPAEKERPT----------------VLTVEMLPA----------PYPPPA 171
                         |:.|:.|::.|                |:|.|...:          ..|...
  Fly    95 -------------PNDPSTKKKTTKRRRGRPRMPLEIVDIVVTNESKASAGESVGGDEFDQPVEI 146

  Fly   172 STPPPAPAGAV--------------------KGKLHVCAICGNGYPRKSTLDTHMRRHNDERPYE 216
            |..|.|....|                    ..::|.|..||.....||:|..|...||..|||.
  Fly   147 SNEPDATDSDVNLEEIDLPDEDGLESDHDLPNVQIHKCDTCGIIKNNKSSLVRHQFEHNGIRPYP 211

  Fly   217 CEICHKSFHVNYQLKRH-IRQHTGAKPYTCQYCQRNFADRTSLVKHERTHRNERPYACKTCGKKF 280
            |:.|.|:|.|..:||.| :..||...|:.|:||.|.:.......||||.|.||||:.|..|||.|
  Fly   212 CKECPKTFLVASELKAHNLTHHTLEPPFACRYCDRRYFSVVGRKKHERVHTNERPFVCDQCGKAF 276

  Fly   281 TYASVLKMHYKTHTGEKPHICQLCNKSFARIHNLVAHLQTQQH 323
            |...:||.|...|...:.:.|.:|::||:...:|..|..:..|
  Fly   277 TRTCILKAHMAVHQVVRKYSCDVCDRSFSLKKHLATHFISNTH 319

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4424	NP_650859.3	zf-AD	10..92	CDD:285071	19/85 (22%)
		C2H2 Zn finger	189..209	CDD:275368	7/19 (37%)
		DUF45	<204..281	CDD:302795	34/77 (44%)
		COG5048	210..>345	CDD:227381	45/115 (39%)
		C2H2 Zn finger	217..237	CDD:275368	8/20 (40%)
		C2H2 Zn finger	245..265	CDD:275368	8/19 (42%)
		zf-H2C2_2	257..282	CDD:290200	14/24 (58%)
		C2H2 Zn finger	273..293	CDD:275368	9/19 (47%)
		zf-H2C2_2	286..310	CDD:290200	8/23 (35%)
		C2H2 Zn finger	301..320	CDD:275368	6/18 (33%)
nom	NP_001262384.1	zf-AD	5..76	CDD:214871	21/107 (20%)
		C2H2 Zn finger	184..204	CDD:275368	7/19 (37%)
		C2H2 Zn finger	212..261	CDD:275368	19/48 (40%)
		zf-H2C2_2	255..278	CDD:290200	14/22 (64%)
		C2H2 Zn finger	269..289	CDD:275368	9/19 (47%)
		zf-H2C2_2	282..305	CDD:290200	7/22 (32%)
		C2H2 Zn finger	297..313	CDD:275368	5/15 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.960