DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4424 and CG17359

DIOPT Version :9

Sequence 1:	NP_650859.3	Gene:	CG4424 / 42390	FlyBaseID:	FBgn0038765	Length:	345	Species:	Drosophila melanogaster
Sequence 2:	NP_648679.1	Gene:	CG17359 / 39549	FlyBaseID:	FBgn0036396	Length:	339	Species:	Drosophila melanogaster

Alignment Length:	372	Identity:	90/372 - (24%)
Similarity:	153/372 - (41%)	Gaps:	80/372 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LNMMTLCRTCLQDGEAHMVSIF-------QTADDRLPGGVSLCDKIESLSGIQIRATAKEEVLPT 62
            :::..:||.|..:.:. ::.|:       ....::.|   .|...:...||..:.   ||:.:|.
  Fly     1 MDISQMCRVCRDESDC-LLDIYTEPYASSNRVQEQEP---VLATMLRECSGCSVH---KEDGMPQ 58

  Fly    63 RICLRCKAFLTLAHKFRQICQRSNEFLRE--YVIKDAVEQGVVKEVVQQTRPSTPPPIETEQLEP 125
            .||:.|...:..|::.|:.|::|:::..:  .::|:..:......:.....|..|.
  Fly    59 FICVECAEAVRNAYRLRRQCRKSHQYFEQLRLMMKELDDIEYCLNIGDNIEPQMPV--------- 114

  Fly   126 PEDEVLEEGVWSTEDPIEETPHGPAEKERPTVLTVEMLPAPYPPPASTP---------------- 174
               .|:|.|         :||    |...|  |.||::...|.||...|
  Fly   115 ---SVMEAG---------KTP----ETSEP--LLVELVQVKYMPPEPKPISSPLPDNNEHKLAQS 161

  Fly   175 -PPAPAGAVKGKLHVCAICGNGYPRKSTLDTHMRRHNDER---------------PYECEICHKS 223
             .||.....|.|....:...|.   ..:.|:.:...:|::               ||.|::|.:|
  Fly   162 YSPAKTPHNKSKRRARSYSDND---SWSPDSELEHEDDDKIWNASKRGKPKRVPGPYRCKLCTQS 223

  Fly   224 FHVNYQLKRHIRQHTGAKPYTCQYCQRNFADRTSLVKHERTHRNERPYACKTCGKKFTYASVLKM 288
            |.....|:.|:|.|||.:||.|..|.|:||.:.:|..|.|.|..|||:.|..|.|:|.....|::
  Fly   224 FTQKQNLEIHMRIHTGERPYKCSLCPRSFAQKGNLQSHTRCHTGERPFGCPNCPKRFRQVGQLQV 288

  Fly   289 HYKTHTGEKPHICQLCNKSFARIHNLVAHLQTQQHINDPRLTAYLST 335
            |.:|||||:|..|..|.:||.:::.|..|:..  |....|.|:...|
  Fly   289 HTRTHTGEQPFKCSKCQQSFKQLNGLQKHMSA--HTRGKRRTSSQET 333

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4424	NP_650859.3	zf-AD	10..92	CDD:285071	18/90 (20%)
		C2H2 Zn finger	189..209	CDD:275368	2/19 (11%)
		DUF45	<204..281	CDD:302795	30/91 (33%)
		COG5048	210..>345	CDD:227381	49/141 (35%)
		C2H2 Zn finger	217..237	CDD:275368	7/19 (37%)
		C2H2 Zn finger	245..265	CDD:275368	8/19 (42%)
		zf-H2C2_2	257..282	CDD:290200	11/24 (46%)
		C2H2 Zn finger	273..293	CDD:275368	6/19 (32%)
		zf-H2C2_2	286..310	CDD:290200	12/23 (52%)
		C2H2 Zn finger	301..320	CDD:275368	6/18 (33%)
CG17359	NP_648679.1	zf-AD	6..88	CDD:285071	18/88 (20%)
		zf-C2H2	215..237	CDD:278523	8/21 (38%)
		C2H2 Zn finger	217..237	CDD:275368	7/19 (37%)
		zf-H2C2_2	229..254	CDD:290200	12/24 (50%)
		C2H2 Zn finger	245..265	CDD:275368	8/19 (42%)
		zf-H2C2_2	257..282	CDD:290200	11/24 (46%)
		C2H2 Zn finger	273..293	CDD:275368	6/19 (32%)
		zf-H2C2_2	286..310	CDD:290200	12/23 (52%)
		C2H2 Zn finger	301..321	CDD:275368	6/21 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	0	0.000