DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4424 and CG10543

DIOPT Version :9

Sequence 1:	NP_650859.3	Gene:	CG4424 / 42390	FlyBaseID:	FBgn0038765	Length:	345	Species:	Drosophila melanogaster
Sequence 2:	NP_001369100.1	Gene:	CG10543 / 37379	FlyBaseID:	FBgn0034570	Length:	1666	Species:	Drosophila melanogaster

Alignment Length:	143	Identity:	50/143 - (34%)
Similarity:	76/143 - (53%)	Gaps:	4/143 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   188 VCAICGNGYPRKSTLDTH-MRRHNDERPYECEICHKSFHVNYQLKRHIRQHTGAK-PYTCQYCQR 250
            :|.:||..:..|:.|..| :|.|..:..:||.|||..|.:...|:||::.||..| ||.|..|..
  Fly   838 ICEVCGEEFQSKNALYQHIIRVHKRDNFFECHICHNRFTLKANLERHVQLHTEIKRPYVCDLCGS 902

  Fly   251 NFADRTSLVKH-ERTHRNERPYACKTCGKKFTYASVLKMHYKTHTGEKPHICQLCNKSFARIHNL 314
            ::....:|.:| ...|.:.....|..|||:|..|..|:.|..:|:.|:||.|..|:::|....:|
  Fly   903 SYFTYPALKEHYSNAHVDVSECKCTLCGKRFGSAKSLQRHLPSHSEERPHCCNYCDQTFKWKTHL 967

  Fly   315 VAHLQTQQHINDP 327
            |.|.|| .|.|:|
  Fly   968 VRHKQT-MHGNEP 979

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4424	NP_650859.3	zf-AD	10..92	CDD:285071
		C2H2 Zn finger	189..209	CDD:275368	7/20 (35%)
		DUF45	<204..281	CDD:302795	26/79 (33%)
		COG5048	210..>345	CDD:227381	42/120 (35%)
		C2H2 Zn finger	217..237	CDD:275368	8/19 (42%)
		C2H2 Zn finger	245..265	CDD:275368	4/20 (20%)
		zf-H2C2_2	257..282	CDD:290200	8/25 (32%)
		C2H2 Zn finger	273..293	CDD:275368	8/19 (42%)
		zf-H2C2_2	286..310	CDD:290200	9/23 (39%)
		C2H2 Zn finger	301..320	CDD:275368	6/18 (33%)
CG10543	NP_001369100.1	C2H2 Zn finger	727..747	CDD:275368
		C2H2 Zn finger	751..773	CDD:275368
		C2H2 Zn finger	781..801	CDD:275368
		PHA00733	<804..860	CDD:177301	7/21 (33%)
		C2H2 Zn finger	811..827	CDD:275368
		C2H2 Zn finger	839..860	CDD:275368	7/20 (35%)
		C2H2 Zn finger	868..888	CDD:275368	8/19 (42%)
		C2H2 Zn finger	897..913	CDD:275368	3/15 (20%)
		C2H2 Zn finger	926..946	CDD:275368	8/19 (42%)
		C2H2 Zn finger	954..975	CDD:275368	8/21 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100