DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4424 and CG1529

DIOPT Version :9

Sequence 1:	NP_650859.3	Gene:	CG4424 / 42390	FlyBaseID:	FBgn0038765	Length:	345	Species:	Drosophila melanogaster
Sequence 2:	NP_001138223.2	Gene:	CG1529 / 33077	FlyBaseID:	FBgn0031144	Length:	512	Species:	Drosophila melanogaster

Alignment Length:	357	Identity:	78/357 - (21%)
Similarity:	135/357 - (37%)	Gaps:	59/357 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 NMMTLCRTC---LQDGEAHMVSIFQTADDRLPGGVSLCDKIESLSGIQIRATAKEEVLPTRICLR 67
            ::..|||.|   |:|.:.|      ..|.||   :::..|:     :.|....:....||.||..
  Fly     7 DLARLCRICLRHLRDRDTH------CPDPRL---IAILQKL-----LDIDILKQPHGFPTEICNL 57

  Fly    68 CKAFLTLAHKFRQICQRSNEFLREY----VIKDAVEQGVVKEVVQQTRPSTPPPIETEQ------ 122
            |...:....:.||:.:.|::.|..:    :..|.|::....|.:::........:|.|.
  Fly    58 CHNAVVYFDELRQVARESSQKLIGWQPVDIAVDRVKEEPPDEGLKENHEENEHELEEEHEKQADG 122

  Fly   123 ---------------LEPPEDEVLEEGVWSTEDPIEETPHGPAEKERPTVLTVEMLPAPYPPPAS 172
                           |:..|||...:   ..|:..::...|...|.|..:...:.....|..|..
  Fly   123 QQVDLSKKQEDQKKILDDREDEEYPD---EYENSQQQLSQGTGSKRRAGLACDQCGKQVYKLPYL 184

  Fly   173 TPPPAPAGAVKGKLHVCAICGNGYPRKSTLDTHMRRHNDE--------RPYECEICHKSFHVNYQ 229
            ............|..:|..|...:.|...|.:|||..:.:        |...||:|::.:.....
  Fly   185 EAHIRSVHQGYSKPFLCRSCDKSFTRYEQLRSHMRNAHPQLEQLQQELRDLICELCNRQYSTKNA 249

  Fly   230 LKRHIRQHTGAKPYTCQYCQRNFADRTSLVKHERTHRN--ERPYACKTCGKKFTYASVLKMHYK- 291
            |..|:::|...|.:.|::|......||.|:.|.|||..  || :.|:.|.:.|.:.|.:..|.:
  Fly   250 LGEHLKRHAQRKEHVCEHCGVAKVTRTELLTHLRTHNPTWER-FKCEQCPQLFRHKSAISRHVRV 313

  Fly   292 THTGEKPHICQLCNKSFARIHNLVAH--LQTQ 321
            .|.|::...|..|.|.|....:.|.|  |.|:
  Fly   314 VHEGQRRFQCGHCEKKFGTHASQVRHERLHTE 345

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4424	NP_650859.3	zf-AD	10..92	CDD:285071	21/84 (25%)
		C2H2 Zn finger	189..209	CDD:275368	7/19 (37%)
		DUF45	<204..281	CDD:302795	24/86 (28%)
		COG5048	210..>345	CDD:227381	34/125 (27%)
		C2H2 Zn finger	217..237	CDD:275368	5/19 (26%)
		C2H2 Zn finger	245..265	CDD:275368	7/19 (37%)
		zf-H2C2_2	257..282	CDD:290200	10/26 (38%)
		C2H2 Zn finger	273..293	CDD:275368	5/20 (25%)
		zf-H2C2_2	286..310	CDD:290200	7/24 (29%)
		C2H2 Zn finger	301..320	CDD:275368	7/20 (35%)
CG1529	NP_001138223.2	zf-AD	11..79	CDD:285071	20/81 (25%)
		C2H2 Zn finger	171..192	CDD:275368	2/20 (10%)
		zf-C2H2_2	201..>257	CDD:289522	13/55 (24%)
		C2H2 Zn finger	201..222	CDD:275368	7/20 (35%)
		C2H2 Zn finger	237..257	CDD:275368	5/19 (26%)
		C2H2 Zn finger	265..285	CDD:275368	7/19 (37%)
		zf-C2H2_8	268..349	CDD:292531	25/79 (32%)
		C2H2 Zn finger	294..315	CDD:275368	5/20 (25%)
		C2H2 Zn finger	323..343	CDD:275368	6/19 (32%)
		C2H2 Zn finger	360..380	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100