DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4424 and si:ch211-276c2.4

DIOPT Version :9

Sequence 1:	NP_650859.3	Gene:	CG4424 / 42390	FlyBaseID:	FBgn0038765	Length:	345	Species:	Drosophila melanogaster
Sequence 2:	XP_002664740.1	Gene:	si:ch211-276c2.4 / 321704	ZFINID:	ZDB-GENE-030131-423	Length:	394	Species:	Danio rerio

Alignment Length:	296	Identity:	75/296 - (25%)
Similarity:	109/296 - (36%)	Gaps:	81/296 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    87 EFLREYVIKDAVEQGVVKEVVQQTRPSTPPPIETEQLEPPEDEVLEEGVWSTEDPIEETPHGPAE 151
            ||....:....:||..|.:.......:.....|.|..|..|||..::.....:|..|:.......
Zfish     2 EFFEVEIDLSELEQSTVSDEEDIEEQADQELNEDEDDEEDEDEDEDDDDDDDDDDDEDEDEDEYY 66

  Fly   152 KERPTVLTVEMLPAPYPPPASTPPPAPAGAVKGKLHVCAICGNGYPRKSTLDTHMRRHN------ 210
            |.:.|           |..:.|            ||.|:.||..|...|:|..|:..|.
Zfish    67 KSKKT-----------PKTSKT------------LHTCSQCGKNYKHISSLRIHLLSHTGEKPFH 108

  Fly   211 ----------------------DERPYECEICHKSF------------------HV--------- 226
                                  .||||.|.:|.:||                  ||
Zfish   109 CDQCEKTYSTLSGLKIHQVVHFSERPYSCSVCGRSFSRLDSCKQHQKTHDKVRDHVCTECGKSFT 173

  Fly   227 -NYQLKRHIRQHTGAKPYTCQYCQRNFADRTSLVKHERTHRNERPYACKTCGKKFTYASVLKMHY 290
             ..|||:|...|:|.||:.|.||.|:|....:...|||.|..|:|:.|..||:.:...:.||.|.
Zfish   174 TFSQLKQHQIIHSGLKPFKCSYCDRSFTQAGNRKSHERIHTGEKPHRCTECGRSYKDLTGLKNHM 238

  Fly   291 KTHTGEKPHICQLCNKSFARIHNLVAHLQTQQHIND 326
            :.|:|||.::|:.|.|.|..:.|:..||:.  |.|:
Zfish   239 RVHSGEKQYVCEHCGKGFNSVSNMRYHLRV--HTNE 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4424	NP_650859.3	zf-AD	10..92	CDD:285071	2/4 (50%)
		C2H2 Zn finger	189..209	CDD:275368	7/19 (37%)
		DUF45	<204..281	CDD:302795	34/132 (26%)
		COG5048	210..>345	CDD:227381	48/173 (28%)
		C2H2 Zn finger	217..237	CDD:275368	10/47 (21%)
		C2H2 Zn finger	245..265	CDD:275368	8/19 (42%)
		zf-H2C2_2	257..282	CDD:290200	9/24 (38%)
		C2H2 Zn finger	273..293	CDD:275368	6/19 (32%)
		zf-H2C2_2	286..310	CDD:290200	11/23 (48%)
		C2H2 Zn finger	301..320	CDD:275368	7/18 (39%)
si:ch211-276c2.4	XP_002664740.1	C2H2 Zn finger	81..101	CDD:275368	7/19 (37%)
		COG5048	<90..369	CDD:227381	52/185 (28%)
		zf-H2C2_2	93..118	CDD:290200	3/24 (13%)
		C2H2 Zn finger	109..129	CDD:275368	0/19 (0%)
		C2H2 Zn finger	137..157	CDD:275368	4/19 (21%)
		C2H2 Zn finger	165..185	CDD:275368	4/19 (21%)
		C2H2 Zn finger	193..213	CDD:275368	8/19 (42%)
		C2H2 Zn finger	221..241	CDD:275368	6/19 (32%)
		zf-H2C2_2	234..258	CDD:290200	11/23 (48%)
		C2H2 Zn finger	249..269	CDD:275368	7/21 (33%)
		C2H2 Zn finger	277..297	CDD:275368
		C2H2 Zn finger	305..325	CDD:275368
		C2H2 Zn finger	333..353	CDD:275368
		zf-H2C2_2	345..370	CDD:290200
		C2H2 Zn finger	361..381	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910