DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4424 and Zkscan4

DIOPT Version :9

Sequence 1:	NP_650859.3	Gene:	CG4424 / 42390	FlyBaseID:	FBgn0038765	Length:	345	Species:	Drosophila melanogaster
Sequence 2:	XP_038952138.1	Gene:	Zkscan4 / 291164	RGDID:	1309004	Length:	480	Species:	Rattus norvegicus

Alignment Length:	279	Identity:	86/279 - (30%)
Similarity:	135/279 - (48%)	Gaps:	32/279 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 LPT----RICLRCK-AFLTLAHKFRQICQRSNEFLREYVIKDAVEQGVVKEVVQQTRPST---PP 116
            :||    |..|.|| |.:|.:...:....::.:.|.::..::::|...::....:.:|.|   |.
  Rat   140 VPTGEWSRELLCCKVALVTSSQDSQSSHSQAMKSLFKHESQESLECSPLQARGLEMKPETRGLPL 204

  Fly   117 PIETEQLEPPEDEVLEEGVWST-EDPIEETPHGPAEKERPTVLTVEMLPAPYPPPASTPPPAPAG 180
            ..|.::.:|      |:.||.. ||.::.:....|.::...:.|.:                 ..
  Rat   205 AEEYKEQKP------EQTVWFLGEDTVQISTSTEASEQEGKLQTTQ-----------------KN 246

  Fly   181 AVKGKLHVCAICGNGYPRKSTLDTHMRRHNDERPYECEICHKSFHVNYQLKRHIRQHTGAKPYTC 245
            |...:...|..||..:.:.|.|..|.|.|..|:|||||.|.|:|..:..|..|.|.|||.|||.|
  Rat   247 ATGNRRFYCHECGKSFAQSSGLTKHKRIHTGEKPYECEDCGKTFIGSSALVIHQRVHTGEKPYEC 311

  Fly   246 QYCQRNFADRTSLVKHERTHRNERPYACKTCGKKFTYASVLKMHYKTHTGEKPHICQLCNKSFAR 310
            :.|.:.|:..::|:||:|||..|:||.|..|||.||.:..|..|:|.||||||..|.||.|:|.|
  Rat   312 EECGKVFSHSSNLIKHQRTHTGEKPYECDDCGKTFTQSCSLLEHHKIHTGEKPFQCNLCGKAFRR 376

  Fly   311 IHNLVAHLQTQQHINDPRL 329
            ..:|:.|.:.......|:|
  Rat   377 SSHLLRHQRIHGDKAAPKL 395

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4424	NP_650859.3	zf-AD	10..92	CDD:285071	9/36 (25%)
		C2H2 Zn finger	189..209	CDD:275368	7/19 (37%)
		DUF45	<204..281	CDD:302795	37/76 (49%)
		COG5048	210..>345	CDD:227381	55/120 (46%)
		C2H2 Zn finger	217..237	CDD:275368	8/19 (42%)
		C2H2 Zn finger	245..265	CDD:275368	7/19 (37%)
		zf-H2C2_2	257..282	CDD:290200	14/24 (58%)
		C2H2 Zn finger	273..293	CDD:275368	9/19 (47%)
		zf-H2C2_2	286..310	CDD:290200	14/23 (61%)
		C2H2 Zn finger	301..320	CDD:275368	8/18 (44%)
Zkscan4	XP_038952138.1	SCAN	47..156	CDD:128708	6/15 (40%)
		zf-C2H2	253..275	CDD:395048	7/21 (33%)
		C2H2 Zn finger	255..275	CDD:275368	7/19 (37%)
		zf-H2C2_2	268..290	CDD:404364	12/21 (57%)
		zf-C2H2	281..303	CDD:395048	10/21 (48%)
		C2H2 Zn finger	283..303	CDD:275368	8/19 (42%)
		COG5048	<307..471	CDD:227381	40/89 (45%)
		C2H2 Zn finger	311..331	CDD:275368	7/19 (37%)
		C2H2 Zn finger	339..359	CDD:275368	9/19 (47%)
		C2H2 Zn finger	367..387	CDD:275368	8/19 (42%)
		C2H2 Zn finger	422..442	CDD:275368
		C2H2 Zn finger	450..470	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	139	1.000	Inparanoid score	I4420
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.960