DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4424 and Opbp

DIOPT Version :9

Sequence 1:	NP_650859.3	Gene:	CG4424 / 42390	FlyBaseID:	FBgn0038765	Length:	345	Species:	Drosophila melanogaster
Sequence 2:	NP_724479.1	Gene:	Opbp / 246618	FlyBaseID:	FBgn0050443	Length:	562	Species:	Drosophila melanogaster

Alignment Length:	349	Identity:	81/349 - (23%)
Similarity:	129/349 - (36%)	Gaps:	84/349 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 SIFQTADDRLPGGVSLCDKIES-----------------LSGIQIRATAKEEVLPTRICLRCKAF 71
            |||   ::|......:|.:.||                 |:.:..| |...:......|..|...
  Fly   124 SIF---ENRNKAEEHICPRAESGGSSQQDGDAKAPVRRKLASVSAR-TGPRDASSVISCGICNTV 184

  Fly    72 LTLAHKFRQICQRSNEFLREYVIKDAVEQGVVK----------EVVQQTRPSTPPPIETEQLEPP 126
            .: :.||.:...|.:|......|:||:..|..:          |:..::...|...:..:..:..
  Fly   185 FS-SEKFLKFHMRIHENRAPKSIQDALPIGAHQQYSELDQFYCEICNKSFDETLLTVHKQMHQQE 248

  Fly   127 EDEVL---------EEGVWSTEDPIEETPHG-----------PAEKERPTVLTVEMLPAPYPPPA 171
            ..|::         .|..:.....|.|.|..           ..:||:|          .:|
  Fly   249 SSEIMCSICNRKFENEVTYQMHQKIHEKPRDSESSRKLAQRTSLDKEKP----------GFP--- 300

  Fly   172 STPPPAPAGAVKGKLHVCAICGNGYPRKSTLDTHMRRHNDERPYECEICHKSFHVNYQLKRHIRQ 236
                             |..|...:.|......|.|.|..|:||.||:|.|:|.|:|.|..|:|.
  Fly   301 -----------------CQYCERVFTRPFEKVKHERVHTGEKPYACEVCGKTFRVSYSLTLHLRT 348

  Fly   237 HTGAKPYTCQYCQRNFADRTSLVKHERTHRNERPYACKTCGKKFTYASVLKMHYKTHTGEKPHIC 301
            ||..:||.|..|.:.|........|.|.|.:||.::|..|.|.|..:..|..|..|||  ||:.|
  Fly   349 HTNIRPYVCTVCNKRFKSHQVYSHHLRIHSSERQFSCDACPKTFRTSVQLYAHKNTHT--KPYRC 411

  Fly   302 QLCNKSFARIHNLVAHLQTQQHIN 325
            .:||:.|:.::.:..|:||.:.|:
  Fly   412 AVCNRPFSSMYAVKNHMQTHKEIS 435

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4424	NP_650859.3	zf-AD	10..92	CDD:285071	16/84 (19%)
		C2H2 Zn finger	189..209	CDD:275368	5/19 (26%)
		DUF45	<204..281	CDD:302795	31/76 (41%)
		COG5048	210..>345	CDD:227381	44/116 (38%)
		C2H2 Zn finger	217..237	CDD:275368	10/19 (53%)
		C2H2 Zn finger	245..265	CDD:275368	5/19 (26%)
		zf-H2C2_2	257..282	CDD:290200	9/24 (38%)
		C2H2 Zn finger	273..293	CDD:275368	6/19 (32%)
		zf-H2C2_2	286..310	CDD:290200	11/23 (48%)
		C2H2 Zn finger	301..320	CDD:275368	5/18 (28%)
Opbp	NP_724479.1	C2H2 Zn finger	254..274	CDD:275368	1/19 (5%)
		C2H2 Zn finger	301..321	CDD:275368	5/19 (26%)
		zf-H2C2_2	316..336	CDD:290200	10/19 (53%)
		C2H2 Zn finger	329..349	CDD:275368	10/19 (53%)
		zf-H2C2_2	341..366	CDD:290200	10/24 (42%)
		C2H2 Zn finger	357..377	CDD:275368	5/19 (26%)
		C2H2 Zn finger	385..405	CDD:275368	6/19 (32%)
		C2H2 Zn finger	411..431	CDD:275368	6/19 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100