DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4424 and si:ch211-162i8.2

DIOPT Version :9

Sequence 1:	NP_650859.3	Gene:	CG4424 / 42390	FlyBaseID:	FBgn0038765	Length:	345	Species:	Drosophila melanogaster
Sequence 2:	XP_021331195.1	Gene:	si:ch211-162i8.2 / 100333435	ZFINID:	ZDB-GENE-110913-56	Length:	1662	Species:	Danio rerio

Alignment Length:	136	Identity:	63/136 - (46%)
Similarity:	79/136 - (58%)	Gaps:	0/136 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly   185 KLHVCAICGNGYPRKSTLDTHMRRHNDERPYECEICHKSFHVNYQLKRHIRQHTGAKPYTCQYCQ 249
            |...|..||..:....:|.||||.|..||||.|:.|.|||.....||.|:|.|||.:|||||.|.
Zfish  1382 KPFTCTQCGKSFRSARSLKTHMRIHTGERPYTCQQCGKSFKQIGTLKGHMRIHTGERPYTCQQCG 1446

  Fly   250 RNFADRTSLVKHERTHRNERPYACKTCGKKFTYASVLKMHYKTHTGEKPHICQLCNKSFARIHNL 314
            ::|....:|..|.|:|..||||.|:.||:.|.||.....|.:.||||||:.||.|.|||.:...|
Zfish  1447 KSFKQSATLKGHMRSHTGERPYTCQQCGQSFYYAGNFAAHKRIHTGEKPYTCQQCGKSFKQSGTL 1511

  Fly   315 VAHLQT 320
            ..|::|
Zfish  1512 KGHIRT 1517

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4424	NP_650859.3	zf-AD	10..92	CDD:285071
		C2H2 Zn finger	189..209	CDD:275368	8/19 (42%)
		DUF45	<204..281	CDD:302795	39/76 (51%)
		COG5048	210..>345	CDD:227381	53/111 (48%)
		C2H2 Zn finger	217..237	CDD:275368	9/19 (47%)
		C2H2 Zn finger	245..265	CDD:275368	7/19 (37%)
		zf-H2C2_2	257..282	CDD:290200	12/24 (50%)
		C2H2 Zn finger	273..293	CDD:275368	7/19 (37%)
		zf-H2C2_2	286..310	CDD:290200	13/23 (57%)
		C2H2 Zn finger	301..320	CDD:275368	8/18 (44%)
si:ch211-162i8.2	XP_021331195.1	COG5048	62..471	CDD:227381
		C2H2 Zn finger	68..88	CDD:275368
		C2H2 Zn finger	96..116	CDD:275368
		C2H2 Zn finger	124..144	CDD:275368
		C2H2 Zn finger	152..172	CDD:275368
		C2H2 Zn finger	180..200	CDD:275368
		C2H2 Zn finger	208..228	CDD:275368
		C2H2 Zn finger	236..256	CDD:275368
		C2H2 Zn finger	264..284	CDD:275368
		C2H2 Zn finger	292..312	CDD:275368
		C2H2 Zn finger	320..340	CDD:275368
		C2H2 Zn finger	349..368	CDD:275368
		C2H2 Zn finger	376..396	CDD:275368
		C2H2 Zn finger	404..424	CDD:275368
		COG5048	428..840	CDD:227381
		C2H2 Zn finger	432..452	CDD:275368
		C2H2 Zn finger	460..480	CDD:275368
		C2H2 Zn finger	488..508	CDD:275368
		C2H2 Zn finger	516..536	CDD:275368
		C2H2 Zn finger	544..564	CDD:275368
		C2H2 Zn finger	572..592	CDD:275368
		C2H2 Zn finger	600..620	CDD:275368
		C2H2 Zn finger	630..650	CDD:275368
		C2H2 Zn finger	658..678	CDD:275368
		C2H2 Zn finger	686..706	CDD:275368
		C2H2 Zn finger	714..734	CDD:275368
		COG5048	737..1152	CDD:227381
		C2H2 Zn finger	742..762	CDD:275368
		C2H2 Zn finger	770..790	CDD:275368
		C2H2 Zn finger	798..818	CDD:275368
		C2H2 Zn finger	826..846	CDD:275368
		C2H2 Zn finger	854..874	CDD:275368
		C2H2 Zn finger	882..902	CDD:275368
		C2H2 Zn finger	910..930	CDD:275368
		C2H2 Zn finger	938..958	CDD:275368
		C2H2 Zn finger	966..986	CDD:275368
		COG5048	990..1374	CDD:227381
		C2H2 Zn finger	994..1014	CDD:275368
		C2H2 Zn finger	1022..1042	CDD:275368
		C2H2 Zn finger	1050..1070	CDD:275368
		C2H2 Zn finger	1078..1098	CDD:275368
		C2H2 Zn finger	1106..1126	CDD:275368
		C2H2 Zn finger	1134..1154	CDD:275368
		C2H2 Zn finger	1162..1182	CDD:275368
		C2H2 Zn finger	1190..1210	CDD:275368
		COG5048	1214..1641	CDD:227381	63/136 (46%)
		C2H2 Zn finger	1218..1238	CDD:275368
		C2H2 Zn finger	1246..1266	CDD:275368
		C2H2 Zn finger	1274..1294	CDD:275368
		C2H2 Zn finger	1302..1322	CDD:275368
		C2H2 Zn finger	1330..1350	CDD:275368
		C2H2 Zn finger	1358..1378	CDD:275368
		C2H2 Zn finger	1386..1406	CDD:275368	8/19 (42%)
		C2H2 Zn finger	1414..1434	CDD:275368	9/19 (47%)
		C2H2 Zn finger	1442..1462	CDD:275368	7/19 (37%)
		C2H2 Zn finger	1470..1490	CDD:275368	7/19 (37%)
		C2H2 Zn finger	1498..1518	CDD:275368	9/20 (45%)
		C2H2 Zn finger	1550..1570	CDD:275368
		C2H2 Zn finger	1578..1595	CDD:275368
		C2H2 Zn finger	1606..1626	CDD:275368
		C2H2 Zn finger	1634..1654	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910