DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4424 and LOC100332787

DIOPT Version :9

Sequence 1:	NP_650859.3	Gene:	CG4424 / 42390	FlyBaseID:	FBgn0038765	Length:	345	Species:	Drosophila melanogaster
Sequence 2:	XP_002660733.3	Gene:	LOC100332787 / 100332787	-ID:	-	Length:	356	Species:	Danio rerio

Alignment Length:	241	Identity:	79/241 - (32%)
Similarity:	112/241 - (46%)	Gaps:	38/241 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    99 EQGVVKEVVQQTRPSTPPPIETEQLEPPED--EVLEEGVWSTEDPIEETPHGPAEKERPTVLTVE 161
            |...|:.|:.......|..|..:....|.|  |:.||    |:: .:|.||        |:||
Zfish    39 EMDFVRVVIGDVSDPQPFRILKDDHNEPRDRVEIKEE----TQE-ADEAPH--------TLLT-- 88

  Fly   162 MLPAPYPPPASTPPPAPAGAVKGKLHVCAICGNGYPRKSTLDTHMRRHNDERPYECEICHKSFHV 226
                         |..|....|..| :|:.||..:.:|..|:.||..|..::||.|..|.|||..
Zfish    89 -------------PETPKRTEKASL-ICSHCGKSFKQKGHLEDHMNTHTGDKPYACVQCGKSFTH 139

  Fly   227 NYQLKRHIRQHTGAKPYTCQYCQRNFADRTSLVKHERTHRNERPYACKTCGKKFTYASVLKMHYK 291
            ...||.|.|.|:|.:.:.||.|.:.|..:.:|..|.|.|..|:|:||..|||.||:|:.||.|..
Zfish   140 KGNLKDHTRIHSGERRFGCQQCGKRFTHKANLTDHSRIHTGEKPFACAQCGKSFTHATSLKTHRL 204

  Fly   292 THTGEKPHICQLCNKSFARIHNLVAHLQTQQHI-NDPRLTAYLSTF 336
            :||||:...|:.|.:.|.    |.|||:....| :|.|  .|:.:|
Zfish   205 SHTGERAFSCEQCGQKFL----LSAHLKRHLKIHSDER--PYVCSF 244

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4424	NP_650859.3	zf-AD	10..92	CDD:285071
		C2H2 Zn finger	189..209	CDD:275368	7/19 (37%)
		DUF45	<204..281	CDD:302795	31/76 (41%)
		COG5048	210..>345	CDD:227381	50/128 (39%)
		C2H2 Zn finger	217..237	CDD:275368	9/19 (47%)
		C2H2 Zn finger	245..265	CDD:275368	7/19 (37%)
		zf-H2C2_2	257..282	CDD:290200	12/24 (50%)
		C2H2 Zn finger	273..293	CDD:275368	10/19 (53%)
		zf-H2C2_2	286..310	CDD:290200	10/23 (43%)
		C2H2 Zn finger	301..320	CDD:275368	7/18 (39%)
LOC100332787	XP_002660733.3	COG5048	<77..314	CDD:227381	68/199 (34%)
		C2H2 Zn finger	102..122	CDD:275368	7/19 (37%)
		zf-H2C2_2	114..139	CDD:290200	11/24 (46%)
		C2H2 Zn finger	130..150	CDD:275368	9/19 (47%)
		C2H2 Zn finger	158..178	CDD:275368	7/19 (37%)
		zf-H2C2_2	170..195	CDD:290200	12/24 (50%)
		C2H2 Zn finger	186..206	CDD:275368	10/19 (53%)
		C2H2 Zn finger	214..234	CDD:275368	7/23 (30%)
		zf-H2C2_2	226..249	CDD:290200	7/21 (33%)
		C2H2 Zn finger	242..262	CDD:275368	1/3 (33%)
		C2H2 Zn finger	270..290	CDD:275368
		zf-H2C2_2	282..306	CDD:290200
		C2H2 Zn finger	298..318	CDD:275368
		zf-H2C2_2	310..335	CDD:290200
		C2H2 Zn finger	326..344	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910