DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4424 and znf982

DIOPT Version :9

Sequence 1:	NP_650859.3	Gene:	CG4424 / 42390	FlyBaseID:	FBgn0038765	Length:	345	Species:	Drosophila melanogaster
Sequence 2:	XP_017207343.2	Gene:	znf982 / 100331424	ZFINID:	ZDB-GENE-131120-1	Length:	600	Species:	Danio rerio

Alignment Length:	182	Identity:	66/182 - (36%)
Similarity:	84/182 - (46%)	Gaps:	36/182 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   185 KLHVCAICGNGYPRKSTLDTHMRRHNDERPYECEICHKSF----HVNY----------------- 228
            |.|.|..||..:.|.|.|..|:|.|..|:||.|.:|.|||    |::.
Zfish   401 KTHKCDHCGKTFLRPSELKKHLRVHTKEKPYSCSVCEKSFTQQSHLSQHQKIHTGVREYMCFACD 465

  Fly   229 -------QLKRHIRQHTGAKPYTCQYCQRNFADRTSLVKHERTHRNERPYACKTCGKKFTYASVL 286
                   .||:|.|.|||.||:.|..|.::|.....|..|||.|..|:||||..|.|.|...|.|
Zfish   466 KTYITAGDLKKHQRIHTGEKPFVCSDCNKSFRHSGHLTAHERIHTGEKPYACTQCEKTFRRPSNL 530

  Fly   287 KMHYKTHTGEKPHICQLCNKSFARIHNLVAHLQTQQ--------HINDPRLT 330
            ..|...||||:||.|:.|.::|.|:..|..||:...        ||:|..||
Zfish   531 NEHMMIHTGERPHKCEQCFQTFLRLAELKKHLRVHAKEKPQGVLHIDDVYLT 582

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4424	NP_650859.3	zf-AD	10..92	CDD:285071
		C2H2 Zn finger	189..209	CDD:275368	8/19 (42%)
		DUF45	<204..281	CDD:302795	36/104 (35%)
		COG5048	210..>345	CDD:227381	55/157 (35%)
		C2H2 Zn finger	217..237	CDD:275368	10/47 (21%)
		C2H2 Zn finger	245..265	CDD:275368	7/19 (37%)
		zf-H2C2_2	257..282	CDD:290200	13/24 (54%)
		C2H2 Zn finger	273..293	CDD:275368	7/19 (37%)
		zf-H2C2_2	286..310	CDD:290200	11/23 (48%)
		C2H2 Zn finger	301..320	CDD:275368	7/18 (39%)
znf982	XP_017207343.2	C2H2 Zn finger	180..200	CDD:275368
		COG5048	204..537	CDD:227381	48/135 (36%)
		C2H2 Zn finger	208..228	CDD:275368
		C2H2 Zn finger	236..256	CDD:275368
		C2H2 Zn finger	264..284	CDD:275368
		C2H2 Zn finger	293..313	CDD:275368
		C2H2 Zn finger	321..341	CDD:275368
		C2H2 Zn finger	349..369	CDD:275368
		C2H2 Zn finger	377..397	CDD:275368
		C2H2 Zn finger	405..425	CDD:275368	8/19 (42%)
		C2H2 Zn finger	433..453	CDD:275368	6/19 (32%)
		C2H2 Zn finger	461..481	CDD:275368	4/19 (21%)
		C2H2 Zn finger	489..509	CDD:275368	7/19 (37%)
		C2H2 Zn finger	517..537	CDD:275368	7/19 (37%)
		zf-H2C2_2	529..554	CDD:316026	11/24 (46%)
		C2H2 Zn finger	545..565	CDD:275368	7/19 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910