DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment psidin and AT5G58450

DIOPT Version :9

Sequence 1:	NP_650858.1	Gene:	psidin / 42389	FlyBaseID:	FBgn0243511	Length:	948	Species:	Drosophila melanogaster
Sequence 2:	NP_200653.2	Gene:	AT5G58450 / 835958	AraportID:	AT5G58450	Length:	1065	Species:	Arabidopsis thaliana

Alignment Length:	1023	Identity:	240/1023 - (23%)
Similarity:	423/1023 - (41%)	Gaps:	224/1023 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAQQQGMDSALFERRLRPVYDNLEVGNNRKALQESEKLLRKHPNLLCARALKGLSLLRLGRYDES 65
            |:.:.|:...:.|||:||::|.::....:.||:....||.|:|....|.|||.|...|:|:.||:
plant    64 MSSKFGLAGGIPERRVRPIWDAIDSRQFKNALKLVTSLLAKYPKSPYALALKALIHERMGKTDEA 128

  Fly    66 HG-CLQTVAEE-------KPTDDSTLQVLSFCYREMEQLDKIVELYQHAVKQNPGNEELLAHLFI 122
            .. ||.  |:|       ...||.||..|....:.::.||.....|.||..:.|.|.||:..||.
plant   129 LSVCLD--AKELLYKDDLALMDDLTLSTLQIVLQRLDHLDLATSCYAHACGKYPNNLELMMGLFN 191

  Fly   123 SHVRVEDYKAQQAVALQLYKAQPKNAYYFWSVISVVFQGIRGPESALPEK--RKIYLGLAQRMVD 185
            .:||...:..||..|:::||...:..:..|:|.|:..|       .|.:|  .|:.| ||:.::.
plant   192 CYVREYSFVKQQQTAIKMYKLAGEERFLLWAVCSIQLQ-------VLCDKSGEKLLL-LAEGLLK 248

  Fly   186 KHIKEGKMETEQEAFLYLHILKLQNKYQEAWEFLTGELCAKLYPGA-PVSMKFELLKELGNWREL 249
            |||....|...:...:|:.:|:.|:||.:|.|.|:|:|.:.|.... .:.::..||....::...
plant   249 KHIASHSMHEPEALMVYISLLEQQSKYNDALEVLSGDLGSLLMIEVDKLRIQGRLLARANDYSAA 313

  Fly   250 NELLQQLLDADRDRWDFYKEY-------------------------IQSSFELLKLTPQGVENGD 289
            .::.:::|:...|.|:.:..|                         |:..|..|      .|...
plant   314 VDVYKKILELSPDDWECFLHYLGCLLEDDSIWKYFDNIDQIHPTKHIECKFSHL------TEEMF 372

  Fly   290 KDSLARCQEFLQRI-IDSSERKKRGPYLARLELHQR-----MRAEQLPAEKLIGDFDEMVIEYFR 348
            ...::...:.:|:: .|:.....||||||.||:.:|     .:.|    :||:    |.:::||.
plant   373 DSRISSASDLVQKLQRDAENSNLRGPYLAELEIEKRKFLFGKKNE----DKLL----ESLLQYFL 429

  Fly   349 LFGDKSCCTHDIALFLPSISMNQRQALASKLLLESGVTSTSLPKNKEQLQKHLCALQISRMCGSH 413
            .||..:|...|:..:|..:|.|::.... ::|:::..:|.|..|   .|.:....|::..:.|:.
plant   430 KFGHLACYASDVEAYLQVLSPNKKAGFV-EMLVKNSDSSASATK---VLGQTTTILKVQELTGNI 490

  Fly   414 MDLPADHLLAFYTALKL------------HYEHGRTTFGKKLLATEMGPSDAYALLAANVMYDLS 466
            ..||.|.:.|  :|:||            ..:...:.||::||:           |.:|::..|.
plant   491 FGLPTDEIEA--SAVKLAKLYCQNLSLSKDLDPQESMFGEELLS-----------LISNMLVQLF 542

  Fly   467 RRENKSDHLFEALCLLQYVLRNSTSNFHV---KLLSLKIYHLFGCQVGAQEMYEYLDIKQIQLDS 528
            .|.....:|.||:.:|:..|   |...||   |:|.|.||...|....|.|.|:.||:|.|..::
plant   543 WRTRDFGYLAEAIMVLELGL---TIRGHVWQYKILLLHIYSYVGALPLAFERYKALDVKNILTET 604

  Fly   529 MGYVHCQLLALGGRFSGNRNVYDATLKFFTNSYKERLEYIALTYRFCTFSKMEEFMNFKERLTNS 593
            :.:...:.:.....:....|:....|||..:..:|..:...|.||...:||:.||:.||:||.:|
plant   605 VSHHILRQMLESPMWVDLSNLLKDYLKFMDDHLRESADLTFLAYRHRNYSKVIEFVLFKQRLQHS 669

  Fly   594 LQYVACSVEAQICDLVSCYGN------ITQNLSAYVAMSIEPAEDRIAWHELSDNRDLGAIIRWD 652
            .||.|..|||.:..|.....:      |.:||.:.|.: :| ..:.|....|..|.|:.....|.
plant   670 NQYQAARVEASVLQLKQNADSFEEEERILENLKSGVQL-VE-LSNEIGSRTLKFNEDMQTRPWWT 732

  Fly   653 PLHE-----------------VDAAEERRESFDQEVEVLQVRSLMLRLFASFIDLYHGAGLKDSP 700
            |..|                 .:..|||.|:..:   .:|.:||:.|:....|.....| ||:|
plant   733 PCPEKNYLLGPFEEISYCPPKENVKEEREENMKR---AIQRKSLLPRMIYLSIQCTPTA-LKES- 792

  Fly   701 AGAET----------ATLELLRESWTGLFQRLRVMNYKPLAQKFLVNLLPTRLHLLLDMPYERFF 755
              .||          ..|:.|.|.:|                    .:|...|
plant   793 --VETNGSGGDIDVCEELKCLLEDYT--------------------KMLGCSL------------ 823

  Fly   756 DDLAQLVLDLQSGSAKLAEQCKRVGDNVIATMELCV----QTINESNESNGIDGLWKRR-GQQQK 815
            .|..:::.::..|    |...:.:|.|::..:...|    .:::.....:.::.|::|. ..:.:
plant   824 SDAVEMITEISQG----ARTSESLGSNLVDWLNFAVFWNAWSLSSQEHWHVLNSLFERLILDRVR 884

  Fly   816 VAASLEMLSLYA---FLLSVLNDKL-------QVSSKT-----KTKKKPVENKVDGPQPISE--K 863
            ...|.:|.|.|:   .|:.::.:.|       |..:::     |.|||...:......|||:  |
plant   885 SMGSSDMSSCYSDVQVLVQIITEPLAWHSLIIQACTRSSLPSGKKKKKNQHSDQLSSSPISQAIK 949

  Fly   864 ERSQMLQELMRQLKHKFEACDTAIRSWKAPVLPRDLSSFMSDMSLKPE 911
            :..|:|             |.|.          :|:|:::.:....||
plant   950 DSIQLL-------------CSTI----------QDVSNWLLNQLNNPE 974

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
psidin	NP_650858.1	TPR_12	42..108	CDD:290160	24/73 (33%)
		TPR repeat	48..74	CDD:276809	11/26 (42%)
		TPR repeat	79..109	CDD:276809	10/29 (34%)
		TPR repeat	114..142	CDD:276809	9/27 (33%)
		NatB_MDM20	264..642	CDD:286836	104/429 (24%)
AT5G58450	NP_200653.2	TPR repeat	143..175	CDD:276809	8/31 (26%)
		TPR repeat	183..213	CDD:276809	11/29 (38%)
		TPR repeat	259..293	CDD:276809	11/33 (33%)
		TPR repeat	298..323	CDD:276809	3/24 (13%)
		NatB_MDM20	366..724	CDD:313088	101/393 (26%)
		TPR_11	<82..>359	CDD:330823	74/286 (26%)
		TPR repeat	108..138	CDD:276809	12/31 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	105	1.000	Domainoid score	I2215
eggNOG	1	0.900	-	-		E1_KOG2053
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	193	1.000	Inparanoid score	I1364
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022953at2759
OrthoFinder	1	1.000	-	-		FOG0004730
OrthoInspector	1	1.000	-	-		oto3181
orthoMCL	1	0.900	-	-		OOG6_102465
Panther	1	1.100	-	-	LDO	PTHR22767
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.870