Protein Alignment psidin and Naa25

DIOPT Version :10

• Sequence 1: NP_650858.1
• Gene: psidin / 42389
• FlyBaseID: FBgn0243511
• Length: 948
• Species: Drosophila melanogaster
• Sequence 2: NP_001400511.1
• Gene: Naa25 / 360811
• RGDID: 1305685
• Length: 972
• Species: Rattus norvegicus
• Alignment Length: 1002
• Identity: 319/1002 - (31%)
• Similarity: 518/1002 - (51%)
• Gaps: 110/1002 - (10%)

  Fly    13 ERRLRPVYDNLEVGNNRKALQESEKLLRKHPNLLCARALKGLSLLRLGRYDESHGCLQTVAEEKP 77
            :|||||:||.|:.|||:.|:|:::|||:||.:|.||:.||.:.|.|.||.:|:....|.||..:|
  Rat    12 DRRLRPIYDYLDNGNNKMAIQQADKLLKKHRDLHCAKVLKAIGLQRTGRQEEAFTLAQEVAALEP 76

  Fly    78 TDDSTLQVLSFCYREMEQLDKIVELYQHAVKQNPGNEELLAHLFISHVRVEDYKAQQAVALQLYK 142
            |||::||.|:..||||.:.:.:.:||:.|||:.|.:||..:|||:::.||.:||..|...:.|||
  Rat    77 TDDNSLQALTILYREMHRPELVTKLYEAAVKKVPNSEEYHSHLFMAYARVGEYKKMQQAGMALYK 141

  Fly   143 AQPKNAYYFWSVISVVFQGIRGPESALPEKRKIYLGLAQRMVDKHIKEGKMETEQEAFLYLHILK 207
            ..|||.||||||:|::.|.|...:..|  .:.::|.||:|||:|.:||.|:|.|.|..||..||:
  Rat   142 IVPKNPYYFWSVMSLIMQSISARDENL--SKTMFLPLAERMVEKMVKEDKIEAEAEVELYYMILE 204

  Fly   208 LQNKYQEAWEFLTGELCAKLYPGAPVSMK----FELLKELGNWRELNELLQQLLDADRDRWDFYK 268
            ...|||||.:.:.|:|..||  .:.:..:    ..:.|:|..|.|.|.|.::||..:.|.|.||.
  Rat   205 RLGKYQEALDVIRGKLGEKL--TSEIQSRENKCMAMYKKLSKWPECNALSRRLLLKNSDDWQFYL 267

  Fly   269 EYIQSSFELLK--LTPQGVENGDKDSLARCQ-----EFLQ-RIIDSSE--RKKRGPYLARLELHQ 323
            .|..|.|.|::  .||........:....|.     :|:: ||.::|:  |..|||:||:|||.:
  Rat   268 TYFDSVFRLIEEAWTPPAEGEHSLEGEVHCSAEDAVKFIEDRITEASQSSRHVRGPHLAKLELIR 332

  Fly   324 RMRAEQLPAEKLIGDFDEMVIEYFRLFGDKSCCTHDIALFLPSISMNQRQALASKLLLESGVTST 388
            |:|::....|..:||.:|::.:||:.||||.||..|:.:|:..:...|.....::||   ||...
  Rat   333 RLRSQGCNDEFRLGDPEELMFQYFKKFGDKPCCFTDLKVFVDLLPAAQCTQFINQLL---GVVPL 394

  Fly   389 S--------LPKNKEQLQKHLCALQISRMCGSHMDLPADHLLAFYTALKLHYEHGRTTFGKKLLA 445
            |        ||.:...||:|||.:|::|:.|.:..:..:..|.....|.|.|:|| ..||:..|.
  Rat   395 STPTEDKLALPADIRGLQQHLCVVQLTRLLGLYHSMDKNQKLDVVRELMLRYQHG-LEFGRSCLK 458

  Fly   446 TEMGPSDAYALLAANVMYDLSRRENKSDHLFEALCLLQYVLRNSTSNFHVKLLSLKIYHLFGCQV 510
            ||:..||.|.|||.:|:.|:.|...:...:::||.||:..|.:|.||...|||.::||.:.|...
  Rat   459 TELQFSDYYCLLAVHVLIDIWREAGEETAVWQALTLLEEGLTHSPSNAQFKLLLVRIYCVLGAFE 523

  Fly   511 GAQEMYEYLDIKQIQLDSMGYVHCQLLALGGRFSGNRNVYDATLKFFTNSYKERLEYIALTYRFC 575
            ...::|..||.|.||.|::||:..:..|..|:::......:..|:||.::.|:..|||...|::.
  Rat   524 PVVDLYSSLDAKHIQHDTIGYLLTRYAASLGQYAAASQSCNFALRFFHSNQKDTSEYIIQAYKYG 588

  Fly   576 TFSKMEEFMNFKERLTNSLQYVACSVEAQICDLVSCYGNITQNLSAYV-AMSIEPAEDRIAWHEL 639
            .|.|:.||:.|:.||.|||.:.....|..:.||: ...||:.:|:..: :|::.|.||.:.|.:|
  Rat   589 AFEKIPEFIAFRNRLNNSLHFAQVRTERMLLDLL-LEANISTSLAESIKSMNLRPEEDDVPWEDL 652

  Fly   640 SDNRDLGAIIRWDPLHEVDAAEERRESFDQEVEVLQVRSLMLRLFASFIDLYHGAGLKDSPAGAE 704
            .|||||.....|||.....:.|.::.|.::|...|::|||.|||.::...|.|....::|...:|
  Rat   653 RDNRDLDVFFSWDPKDRNVSEEHKKLSLEEETMWLRIRSLTLRLISALPSLTHPVEPRNSEKTSE 717

  Fly   705 ---TATLELLRESWTGLFQRLRV-------MNYKPLAQKFLVNLLPTRL---------------- 743
               ::.:::||.    |.|:|.|       ...|.:...|| ..:|||:
  Rat   718 NGVSSRVDVLRL----LLQQLEVAVETGKRFIEKEIQYPFL-GPVPTRMGRFFSSGCCQCQVHSF 777

  Fly   744 HLLLDMPYERFFDDLAQLVLDLQSGSAKLAEQCKRVGDNVIATMELCVQTINESNESNGI----- 803
            ||:.|: ||          || .||.....:..:|:.:::.:.:||.          .|:
  Rat   778 HLVSDV-YE----------LD-TSGLEGTVDIQERIENSLASLLELL----------KGVFSTCK 820

  Fly   804 -DGLWKRRGQQQKVAASLEMLSLYAFLLSVLNDKLQVSSKTKTKKKPVENKVDGPQPISEKERSQ 867
             |.|..:.|..:...|.||.|..:...:|::   |.|||..::..:|.:..:...:. .:||.|.
  Rat   821 GDLLEVKDGNVKTQPAVLENLVFFVETISIV---LWVSSYCESVLRPYKLNIQKKKK-KKKETSI 881

  Fly   868 MLQELMRQLKHKFEACDTA-------IRSWKAPVLPRDLSSF-MSDMSLKPE---VEATLIGDVS 921
            ::..:....:.......|.       |:..:|.::...|... :.|.|:.||   ...|:.|.|.
  Rat   882 VMPPIFTSFQDYVTGLQTVISNAVDHIKGLEAHLIALKLEELTLEDTSISPEERKFSRTVQGKVQ 946

  Fly   922 ATFKDSHELMVTELRNLLKDKIRMVAK 948
            :::  .|.|:  |...||:.::....|
  Rat   947 SSY--LHSLL--ETGELLRKRLETTKK 969

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
psidin	NP_650858.1	TPR repeat	114..142	CDD:276809	11/27 (41%)
		NatB_MDM20	264..645	CDD:430834	133/399 (33%)
		Spy	1..>151	CDD:443119	65/137 (47%)
		TPR repeat	48..74	CDD:276809	10/25 (40%)
		TPR repeat	79..109	CDD:276809	13/29 (45%)
Naa25	NP_001400511.1	TPR 1	11..44		18/31 (58%)
		BepA	21..146	CDD:443813	55/124 (44%)
		TPR 2	45..78		13/32 (41%)
		TPR repeat	47..73	CDD:276809	10/25 (40%)
		TPR repeat	78..108	CDD:276809	13/29 (45%)
		TPR 3	79..112		14/32 (44%)
		TPR 4	114..146		13/31 (42%)
		NatB_MDM20	263..658	CDD:430834	133/399 (33%)