Protein Alignment psidin and naa25

DIOPT Version :10

• Sequence 1: NP_650858.1
• Gene: psidin / 42389
• FlyBaseID: FBgn0243511
• Length: 948
• Species: Drosophila melanogaster
• Sequence 2: NP_595632.1
• Gene: naa25 / 2540082
• PomBaseID: SPBC1215.02C
• Length: 811
• Species: Schizosaccharomyces pombe
• Alignment Length: 916
• Identity: 190/916 - (20%)
• Similarity: 354/916 - (38%)
• Gaps: 220/916 - (24%)

  Fly    54 LSLLRLGRYDESHGCLQTVAEEKPTDDSTLQVLSFCYREMEQLDKIVE--LYQHAVKQNPGNEE- 115
            |||.:.||..|:...|:.:   |.|..::|::|.......:...|..|  ::.....|..|.:|
pombe    16 LSLAQAGRGPEALALLEPL---KSTPINSLELLDIIQAVYDDQKKGEESFVFWEKFLQTYGKQEK 77

  Fly   116 -LLAHLFISHVRVEDYKAQQAVALQLYKAQPKNAYYFWSVISVVFQGIRGPESALPEKRKIYLGL 179
             |||: |.:.:|::....|:..|::|.|..|...:..| |||.::...:..|:.:.::      |
pombe    78 NLLAY-FKASIRIKSLSHQRKAAVELQKNFPSRKHTLW-VISSLYLLSKKSENEVEQR------L 134

  Fly   180 AQRMVDKHIK------EGKMETEQEAFLYLHILKLQNK---------YQEAWEFLTGELCAKLYP 229
            .:.:.:|..|      .|.:::.:|..|||.:|.|...         :|:|..|:..:....|
pombe   135 LKALAEKTAKLIFEKPTGYIDSCEEFHLYLDVLLLVGDKDRALDALIHQDADRFVDADADLLL-- 197

  Fly   230 GAPVSMKFELLKELGNWRELNELLQQLLDADRDRWDFYKEYIQSSFELLKLTPQGVENGDKDSLA 294
                 .|.|||.....|..|......|.......|...|..:.|:            :.|...|.
pombe   198 -----RKLELLASCARWDSLFTFSLSLFQTGNTDWKVCKALLDSA------------SNDDSKLV 245

  Fly   295 RCQEFLQRIIDSSERKKRGPYLARLELHQRMRAEQLPAEKLIGDFDEMVIEYFRLFGDKSCCTHD 359
            ..::.:.:.:.:|. .||..:|..:|...|...|         :.:..::.|.:....|.....|
pombe   246 PLKDCILKALSTSS-TKRNLHLLWIEASARFFPE---------EHESALLGYIKKLYMKPIVFED 300

  Fly   360 IALFLPSISMN-QRQALASKLLLESGVTSTSLPKNKEQLQKHLCALQISRMCGSHMDLPADHLLA 423
            :..:|..:::: |.:.|.:..|.:.|.::.|  :..::|...:..|:|             |.|.
pombe   301 LRPYLLKLNVDAQHRLLDAFKLADLGESNES--QKVDKLYAEVLLLKI-------------HFLL 350

  Fly   424 F--YTALK---------LHYEHGRTTFGKKLLATEMGPS-DAYALLAANVMY------DLSRREN 470
            |  :||..         :.:|.| .:..|.||.|:.... :|..|...:::|      ||...|
pombe   351 FESFTAESVVDYVRRCFVAFEKG-LSLSKGLLPTDFTHGYEALLLAVHSLIYMWEGNKDLKPAE- 413

  Fly   471 KSDHLFEALCLLQYVLRNSTSNFHVKLLSLKIYHLF-GCQVGAQEMYEYLDIKQIQLDSMGYVHC 534
            |...:|:|:|||:..:..|..|||:||..:::|.|. |....|.::|:.:.|||||.|::.:
pombe   414 KQALIFDAICLLEKGITYSQHNFHLKLPLIRLYLLLDGGFPAAAKVYDTMSIKQIQNDTLDH--- 475

  Fly   535 QLLALGGRF---SGNRNVYDATLKFFTNSYKERLEYIALTYRFCTFSKMEEFMNFKERLTNSLQY 596
            .||.....:   |...:..:::||.:.::..|..|.|::.|....:|::|:..||:.||.:|...
pombe   476 YLLTRATTYYPSSVTSHYINSSLKIYGSNEFETPEMISMAYEDGAYSQIEDMRNFRSRLDHSTWK 540

  Fly   597 VACSVEAQICDLVSCYGNITQNLSAYVAMSIEPAEDRIAWHELSDNRDLGAIIRWDPLHEVDAAE 661
            ....||......::.:....|    |:.....|          .|||||...        .|...
pombe   541 SISLVERARIHYLTAFKPPKQ----YLPKCSSP----------KDNRDLKVF--------ADYGS 583

  Fly   662 ERRESFDQEVEVLQVRSLMLRLFASFIDLYHGAGLKDSPAGAETATLELLRESWTGLFQRLRVMN 726
            ::..:.::                         .|::||   :..||      |.    .|.|:.
pombe   584 DKLPTVEE-------------------------SLRNSP---KPDTL------WI----HLTVIG 610

  Fly   727 YKPLAQKFLVN-------LLPTRLHLLL---DMPYERFFDDLAQLVLDLQSG--SAKLAEQCKRV 779
            :. |.|..:||       |....:.:|.   |:..:...:::..:.|.:|.|  |.|:     :.
pombe   611 HS-LVQDSIVNGDFEKAVLSAKEMEVLCENNDLSKQLTSEEIVHMKLLIQLGLLSVKV-----KN 669

  Fly   780 GD---NVIATMELCVQTINESNESNGIDGLWKRRGQQQKVAASLEMLSLYAFLLSVLNDKLQVSS 841
            ||   :...|:|..:::.:..|                  :..|..|:.|.   .::||.:...:
pombe   670 GDYENSSFETIENLIESFDYEN------------------STPLSQLTKYT---EIINDLITCLN 713

  Fly   842 K-----TKTKKKPVENKVDGPQPISEKERSQMLQELMRQLKHKFEACDTAIRSWKAPVLPRDLSS 901
            .     :.||||....:....:.||    |..|..:....|||.:|.    |.:.:.:|.   :|
pombe   714 SFLYHVSATKKKEFTRQYQLLKNIS----SNKLGSISGITKHKKKAA----RKYVSELLS---NS 767

  Fly   902 FMSDMS 907
            ::|::|
pombe   768 WLSNLS 773

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
psidin	NP_650858.1	TPR repeat	114..142	CDD:276809	9/29 (31%)
		NatB_MDM20	264..645	CDD:430834	88/403 (22%)
		Spy	1..>151	CDD:443119	26/100 (26%)
		TPR repeat	48..74	CDD:276809	7/19 (37%)
		TPR repeat	79..109	CDD:276809	4/31 (13%)
naa25	NP_595632.1	NatB_MDM20	227..558	CDD:430834	82/372 (22%)