Protein Alignment psidin and psidin

DIOPT Version :10

• Sequence 1: NP_650858.1
• Gene: psidin / 42389
• FlyBaseID: FBgn0243511
• Length: 948
• Species: Drosophila melanogaster
• Sequence 2: XP_321109.6
• Gene: psidin / 1281170
• VectorBaseID: AGAMI1_007237
• Length: 990
• Species: Anopheles gambiae
• Alignment Length: 1010
• Identity: 423/1010 - (41%)
• Similarity: 623/1010 - (61%)
• Gaps: 87/1010 - (8%)

  Fly     3 QQQGMDSALFERRLRPVYDNLEVGNNRKALQESEKLLRKHPNLLCARALKGLSLLRLGRYDESHG 67
            ||:.:   .:||:|||:::::|:||.:||||:.||:|:|.|.|.||||||..:..||||.::|..
Mosquito     2 QQEDL---AYERKLRPIWESIEIGNYKKALQDVEKMLKKKPTLQCARALKAWAYQRLGRTEDSAP 63

  Fly    68 CLQTVAEEKPTDDSTLQVLSFCYREMEQLDKIVELYQHAVKQNPGNEELLAHLFISHVRVEDYKA 132
            .:..:.||:|.:.:||..|:..|:|.::||||..|:.:||:|.||:||||:.|||:::|::|:||
Mosquito    64 LIAALEEEQPIEATTLHALTLYYKETQRLDKICTLFSNAVRQVPGSEELLSQLFIAYMRIDDFKA 128

  Fly   133 QQAVALQLYKAQPKNAYYFWSVISVVFQGIRGPESALPEKRKIYLGLAQRMVDKHIKEGKMETEQ 197
            .|:|||||||.:|:|:||||:|:|||.|.:|||::...:|.::.|.||||||||.|.|.|:|..|
Mosquito   129 LQSVALQLYKLRPRNSYYFWAVMSVVLQALRGPDAHNAQKAQLLLVLAQRMVDKFIAENKLEGAQ 193

  Fly   198 EAFLYLHILKLQNKYQEAWEFLTGELCAKLYPGAPVSMKFELLKELGNWRELNELLQQLLDADRD 262
            ||.|||.||:.|:||.||::||.|.||.||||||||.::.:|||:|..|.|||.||::||..::|
Mosquito   194 EAQLYLQILQEQHKYSEAYDFLQGALCQKLYPGAPVYLRIDLLKQLNKWGELNRLLKELLLQEQD 258

  Fly   263 RWDFYKEYIQSSFELLKL--TPQGVENGDKDSLARCQEFLQRIIDSSERKKRGPYLARLELHQRM 325
            |||:|::||.|:|||::.  .|.|.:.    ::..|.|||..||::..:|.||||||||||::||
Mosquito   259 RWDYYQDYINSTFELIRAGEKPDGADY----TVEMCHEFLCDIIEAQPKKFRGPYLARLELNRRM 319

  Fly   326 RAEQLPAEKLIGDFDEMVIEYFRLFGDKSCCTHDIALFLPSIS-MNQRQALASKLLLESGVTSTS 389
            ..::..||:|.|...:|:.|||.||.||.||..|:.|||..:. .::|:.||:||:...|::|.:
Mosquito   320 VEQRYAAEQLFGKMSDMLAEYFELFADKPCCALDMKLFLEFVKPAHERRTLATKLMNGLGLSSAT 384

  Fly   390 LPKNKEQLQKHLCALQISRMCGSHMDLPADHLLAFYTALKLHYEHGRTTFGKKLLATEMGPSDAY 454
            ||.:|||:|:|:|.|||:|..|:|..:..:.|.|.||:|.||||||...:|:.||.|:|||||||
Mosquito   385 LPASKEQMQRHICTLQIARYSGAHAIVSEELLHAIYTSLSLHYEHGYNAYGQGLLVTDMGPSDAY 449

  Fly   455 ALLAANVMYDLSRRENKSDHLFEALCLLQYVLRNSTSNFHVKLLSLKIYHLFGCQVGAQEMYEYL 519
            |||||.:||:.:.|..:|:...||||||.::|.||.:|||.|||:|::||..|....||..||.|
Mosquito   450 ALLAAQIMYERAYRMQRSEPAIEALCLLNHLLGNSVNNFHGKLLALQLYHRLGLTQAAQSAYETL 514

  Fly   520 DIKQIQLDSMGYVHCQLLALGGRFSGNRNVYDATLKFFTNSYKERLEYIALTYRFCTFSKMEEFM 584
            |||.|||||:||:||..||..|..:..:..|:.||.||.|......|:....|.|.||||:.|.:
Mosquito   515 DIKHIQLDSLGYLHCAQLANAGFPALAKATYEQTLYFFLNDIDANSEFPKALYNFGTFSKLVEIV 579

  Fly   585 NFKERLTNSLQYVACSVEAQICDLVSCYGNITQNLSAYVAMSIEPAEDRIAWHELSDNRDLGAII 649
            :|:.||.||..::..:||..:..:||..|.::|.|:||.....:||||||.|.:|.|||||...:
Mosquito   580 DFRSRLANSYHFMLVTVETLLLMVVSSGGTLSQLLAAYRQTRRKPAEDRIRWDKLHDNRDLTIFV 644

  Fly   650 RWDPLHE-----------------------VDAA---------EERRE-----SFDQEVEVLQVR 677
            .|||..:                       |.||         |||||     |::|:.::|::|
Mosquito   645 SWDPPSDEEEQEEKKDKPMDNGTGGEKEAPVVAAVTKPVGATLEERRERLQKRSYEQDYDLLRLR 709

  Fly   678 SLMLRLFASFIDLYHGAGLKDSPAGAETATLELLRESWTGLFQRLRVMNYKPLAQKFLVNLLPTR 742
            :.:.::..|.::|:.      |....|.:..:.||:.|..:...:|...:.|::.::||||||:|
Mosquito   710 TGLSKMLFSLVELHL------SRTSVECSAAQQLRDDWVTVAADIRSKQHAPISGRYLVNLLPSR 768

  Fly   743 LHLLLDMPYERFFDDLAQLVLDLQSGSA-----KLAEQCKRVGDNVIATMELCVQTINESNESNG 802
            |||.|.:||||.|..||..||||..|.:     ..|::|......:..||:..::|.::|
Mosquito   769 LHLYLSLPYERVFTQLADFVLDLWKGYSIEQLTLAADKCSGDVTAIHETMKRAIETYHQS----- 828

  Fly   803 IDGLWKRRGQQQKVAASLEMLSLYAFLLSVLNDK--------LQVSSKTKTKKKPVENKV----- 854
            .|.||..:...:.|...:||:||..|||:|..||        .|.|:..|.||.| ||..
Mosquito   829 ADLLWHWKMTHELVNGCIEMISLMVFLLAVCYDKYLHAPTSQAQPSAGKKVKKGP-ENSAPNTAT 892

  Fly   855 ------DGPQPISEKERSQMLQELMRQLKHKFEACDTAIRSWKAPVLPRDLSSFMSDMSLKPEVE 913
                  |....:.|:||..::.:::|:||....|.|..:.|||.|::...||:.:..|||.|:..
Mosquito   893 TTNASNDASSVVPERERLVLVTKVLRELKQTINAMDLLLASWKPPLVEDSLSAAIERMSLNPKCA 957

  Fly   914 ATLIGDVSATFKDSHELMVTELRNLLKDKIRMVAK 948
            :|    |.:|..::....|.|||.|||||:::::|
Mosquito   958 ST----VQSTIAENALTEVRELRKLLKDKLKLMSK 988

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
psidin	NP_650858.1	TPR repeat	114..142	CDD:276809	17/27 (63%)
		NatB_MDM20	264..645	CDD:430834	178/383 (46%)
		Spy	1..>151	CDD:443119	71/147 (48%)
		TPR repeat	48..74	CDD:276809	10/25 (40%)
		TPR repeat	79..109	CDD:276809	12/29 (41%)
psidin	XP_321109.6	None