Protein Alignment psidin and naa25

DIOPT Version :10

• Sequence 1: NP_650858.1
• Gene: psidin / 42389
• FlyBaseID: FBgn0243511
• Length: 948
• Species: Drosophila melanogaster
• Sequence 2: XP_002940168.2
• Gene: naa25 / 100038044
• XenbaseID: XB-GENE-486846
• Length: 970
• Species: Xenopus tropicalis
• Alignment Length: 1011
• Identity: 314/1011 - (31%)
• Similarity: 505/1011 - (49%)
• Gaps: 130/1011 - (12%)

  Fly    13 ERRLRPVYDNLEVGNNRKALQESEKLLRKHPNLLCARALKGLSLLRLGRYDESHGCLQTVAEEKP 77
            :|||||:||.|:.|||:.|:|::||||:||.:|.||:.||.:.|.|.|:.:|:....|.||..:|
 Frog    12 DRRLRPIYDYLDNGNNKMAIQQAEKLLKKHKDLHCAKVLKAIGLQRTGKQEEAFILAQEVAALEP 76

  Fly    78 TDDSTLQVLSFCYREMEQLDKIVELYQHAVKQNPGNEELLAHLFISHVRVEDYKAQQAVALQLYK 142
            |||::||.|:..||||.:.:.:.:||:.|||:.|.:||..:|||:::.||.:||..|...:.|||
 Frog    77 TDDNSLQALTILYREMHRPELVTKLYEAAVKKIPTSEEYHSHLFMAYARVGEYKKMQQAGMALYK 141

  Fly   143 AQPKNAYYFWSVISVVFQGIRGPESALPEKRKIYLGLAQRMVDKHIKEGKMETEQEAFLYLHILK 207
            ..|||.||||||:|::.|.|...:..|  .:.::|.||:|||:|.:||.|:|.|.|..||..||:
 Frog   142 IVPKNPYYFWSVMSLIMQSISAQDENL--SKTMFLPLAERMVEKMVKEDKIEAEAEVELYYMILE 204

  Fly   208 LQNKYQEAWEFLTGELCAKLYPGAPVSMK--FELLKELGNWRELNELLQQLLDADRDRWDFYKEY 270
            ...|::||.:.:.|:|..||........|  ..:.|:|..|.|.|.|.::||..:.|.|.||..|
 Frog   205 RLGKHEEALKVIRGKLGEKLTSELQSREKKCMAMYKKLNKWPECNALSKRLLLQNSDDWQFYLSY 269

  Fly   271 IQSSFELL--KLTP----QGVENGDKD-SLARCQEFLQRIID---SSERKKRGPYLARLELHQRM 325
            ..|.|.|:  ..||    |....||.| |:.:..:|::..|:   :|:|:.|||:||:|||.:|:
 Frog   270 FDSVFHLIDEAWTPPTEGQMSLEGDLDHSIVQAVKFVEDQIENESNSQRQLRGPHLAKLELIRRL 334

  Fly   326 RAEQLPAEKLIGDFDEMVIEYFRLFGDKSCCTHDIALFLPSISMNQRQALASKLL--------LE 382
            |......|..:|:.::::.:||..||||.||..|:.:|:..:|.:|..:..::||        .|
 Frog   335 RKRGCNDEYKLGEPEDLMYQYFIKFGDKPCCLTDLKVFVDLLSASQHTSFINRLLGSLPLNRAAE 399

  Fly   383 SGVTSTSLPKNKEQLQKHLCALQISRMCGSHMDLPADHLLAFYTALKLHYEHGRTTFGKKLLATE 447
            |.:   :||::.:.||:|||.:|:.|:.|.:..:...........:...|.|| ..|||..|.||
 Frog   400 SEI---ALPEDTKALQRHLCVVQLMRLLGIYHKMDKLEKQDAVREMTERYRHG-LQFGKSCLKTE 460

  Fly   448 MGPSDAYALLAANVMYDL-SRRENKSDHLFEALCLLQYVLRNSTSNFHVKLLSLKIYHLFGCQVG 511
            :..||.|.||.|:::.|| |..|..:  ::..|.||:..|.||.||...|||.::||...|....
 Frog   461 LQFSDYYCLLGAHMLLDLWSNGEEWA--VWHCLTLLEEGLNNSPSNAQFKLLLIRIYCSLGAFEP 523

  Fly   512 AQEMYEYLDIKQIQLDSMGYVHCQLLALGGRFSGNRNVYDATLKFFTNSYKERLEYIALTYRFCT 576
            |.::|..||.|.||.|::||:..:.....|:::......:|.|:||.::.|:..|||...|::..
 Frog   524 AMDLYSSLDAKHIQHDTIGYLLTRFAGPLGQYTSASQACNAALRFFHSNQKDTSEYIIQAYKYGA 588

  Fly   577 FSKMEEFMNFKERLTNSLQYVACSVEAQICDLVSCYGNITQNLSAYV-AMSIEPAEDRIAWHELS 640
            |.|:.||:.|:.||.|||.:.....|..:.||: ...:::.:|...: :||:.|.||.|.|.:|.
 Frog   589 FEKIPEFIAFRNRLNNSLHFAQVRTERMLLDLL-LEADVSSSLEESIKSMSLSPEEDDIPWKDLR 652

  Fly   641 DNRDLGAIIRWDPLHEVDAAEERRESFDQEVEVLQVRSLMLRLFASFIDLYHGAGLKDSPAGAE- 704
            |||||.|:..|||.....:.:.|:.|.::|...|::|||.|||.:....|.|....|:|..|||
 Frog   653 DNRDLTALFNWDPKDRDISEDHRKLSLEEESIWLRIRSLTLRLVSGLTALSHTPEPKNSQKGAEN 717

  Fly   705 --TATLELLRESWTGLFQRL-------RVMNYKPLAQKFLVNLLPTRLH---------------L 745
              ::.::::|    .|.|:.       :..|.:.:...|| ....|||.               |
 Frog   718 GVSSKIDIVR----ALLQQFEATVDAGKTFNERQIKYPFL-GPPATRLSKFLSSGACQCQKEALL 777

  Fly   746 LLDMPYE---------------------RFFDDLAQL-------VLDLQSGSAKLAEQCKRVGDN 782
            ||:..|:                     ...:||..|       ::|:|.|:.       |...:
 Frog   778 LLNDIYDLDMSGIDDTCEIQAKIGRKLKSSLEDLQDLLHHCKGNLMDIQGGNC-------RTSPH 835

  Fly   783 VIATMELCVQTINESNESNGIDGLWKRRGQQQKVAASLEMLSLYAFLLSVLNDKLQVSSKTKTKK 847
            :|..:...|:||:..        ||              :.|.:..:|......||     |.||
 Frog   836 IIENLVFFVETISLF--------LW--------------VSSYFVGVLRPFKSNLQ-----KKKK 873

  Fly   848 KPVENKVDGPQPISEKERSQMLQELMRQLKHKFEACDTAIRSWKAPVLPRDLSSFMSDMSLKPEV 912
            |..::....|......:....||.|:..:.......:.::.:.|...|..|..:|..|   :.:.
 Frog   874 KKKDSCATPPVFTGFLDYITGLQTLLSNMSDHIGGLEISLTALKLEDLSLDNITFSED---EKKF 935

  Fly   913 EATLIGDVSATFKDSHELMVTELRNLLKDKIRMVAK 948
            ....:..|.:::..|    :.|:.:||:.::....|
 Frog   936 TKLAVDKVHSSYLHS----LQEMGDLLRKRLETFKK 967

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
psidin	NP_650858.1	TPR repeat	114..142	CDD:276809	11/27 (41%)
		NatB_MDM20	264..645	CDD:430834	134/400 (34%)
		Spy	1..>151	CDD:443119	65/137 (47%)
		TPR repeat	48..74	CDD:276809	9/25 (36%)
		TPR repeat	79..109	CDD:276809	13/29 (45%)
naa25	XP_002940168.2	BepA	21..146	CDD:443813	55/124 (44%)
		TPR repeat	47..73	CDD:276809	9/25 (36%)
		TPR repeat	78..108	CDD:276809	13/29 (45%)
		NatB_MDM20	263..657	CDD:430834	134/400 (34%)