Protein Alignment CG31213 and CG8908

DIOPT Version :9

• Sequence 1: NP_001262752.1
• Gene: CG31213 / 42382
• FlyBaseID: FBgn0051213
• Length: 1809
• Species: Drosophila melanogaster
• Sequence 2: NP_611464.3
• Gene: CG8908 / 37293
• FlyBaseID: FBgn0034493
• Length: 1626
• Species: Drosophila melanogaster
• Alignment Length: 1819
• Identity: 442/1819 - (24%)
• Similarity: 813/1819 - (44%)
• Gaps: 351/1819 - (19%)

  Fly    14 LLW----KDIKLQLTNWVELVMIIFLSALMPIFFSIGTKVAKSIF--PPDIEMEKSPGPKSVNTS 72
            |||    |..:.|.:|.:..|:||....::.:.::     |.::|  |.:....|.| |.::.|.
  Fly    16 LLWLVICKTARFQFSNTLTSVIIIVGPIVVFLVYA-----ATALFREPQEETSVKYP-PVNITTK 74

  Fly    73 LFVDLYFTPNNGILEQLITQLANISEFKSV--EVFDTNSELYLQLMINRNA---IGIAFPSEWYD 132
            : ..:|::|.|.:|..:|..:  :.:.|:|  :.|.:.|||. :.:|.::.   :||.|...:.|
  Fly    75 V-PYIYYSPENLVLAAVIEDV--VHDLKAVGSKAFASASELN-KALIGKDTYGYVGIEFDDSFSD 135

  Fly   133 IKSCPEVLNLTIFM--PLSIKRK----------------DFKYFE-SGFLLLQERISKIFIFFKN 178
            |...|  :|:|:.:  ||.:::.                |..|:: .|||::|.::|:..|..||
  Fly   136 INELP--INVTVGLRFPLHLRKNPKMVWDNTSILKHSKMDVDYYQVEGFLVVQAKLSEALIRAKN 198

  Fly   179 AGNGKIPRVLMNHFPYPSYV---PNHYAESAKAMTYMTLISFFLPCITIAKYVVAEKERHQKAVL 240
            .. ..:|.|::.|:|..:.|   .|..|........:|:.:.:|     |:.:|.|:..|.:.:|
  Fly   199 EA-VVLPEVILQHYPDVAEVDRLDNRVALGGVLFLPVTISAAYL-----AQMIVMERRDHLRDML 257

  Fly   241 TAMGFSNSIHWLAWYTKSMLLL-----LLCLLIMISIFSIGLIYEFSSLVCLMTIFLVYIHSLVL 300
            ..||....|:||:|:..:.|||     .:.||:....||:    ..||||  :...|||...::.
  Fly   258 ELMGVRAWIYWLSWFLVAFLLLSIPTVFMVLLLKWRYFSL----SDSSLV--LFFLLVYNLEVLT 316

  Fly   301 FAFFISSFFSRSLSAVVATILMYFSTALPF-LIVGAENSSVAAQTAASIGLNSALFYILDSVAVM 364
            .||.||||||.::...||.::::....||: |::.....::.......:.|||:|...|......
  Fly   317 SAFMISSFFSDTVGVQVAIVIVHLIGCLPWRLLLMGYVPTLPRTIFVCLFLNSSLAMGLQQFIKS 381

  Fly   365 EMQSVGAQW-YTIDNTASSGYKLSIVGYMLIMISISWIELLICLYIEAVRTGEFEVPQPWSYPFQ 428
            |...:|..| |..:.|....: :.:...:|.|:....:.:|:..|:|.:|:.:   .:.|.:|.|
  Fly   382 ENLRLGLHWTYLFERTDWDEF-VHLGPILLFMLFGCLLRILVLAYMEQLRSYQ---NRKWYFPVQ 442

  Fly   429 RRYWCPLRYGSSVFHQGALLPLAGKNSEGNLPAAHPTRQPIIYLDDRTQENFQRVNISKKIGIEV 493
            ..:||  |:                           .|:|  ..||...|..:.......:.:..
  Fly   443 PSFWC--RW---------------------------NRRP--RSDDFDVEGQETGIRGHPLIVRA 476

  Fly   494 RSLSKTFGFRNVVKDLFFNVYENEITALVGHKGSGKTTIIMMLCGILQPTTGTVLINGYDIVTEA 558
            |::.|.|.....||||..|.|::|||..:||..|||:||:|:|.|.|:|:.|.:.|||||:.|..
  Fly   477 RNIEKVFNEWIAVKDLNLNFYQDEITVFLGHNDSGKSTILMLLAGFLRPSAGEITINGYDLATNQ 541

  Fly   559 KVAKSSLGICPQHSVIFKGMSARDHIYFFSRVKGYNKTEAMMESNIYISKLGLVDSQKWDAMRLS 623
            :.|:.|:.||||.:|:|:.::||.|:.|:.|:||.|:.||..|::.|:....|.|........|.
  Fly   542 RKARQSMCICPQPNVLFEKVNARWHLQFYCRLKGLNRQEASAETDKYLEIGRLQDFANTKVKNLP 606

  Fly   624 PGNQRRLSLACALCAGSKVILCDEPSSGLDPIGRHELMRFLQKEKHGRTILMTTQQLEEGEILAD 688
            .|.:|.|.|.|.||..||::|.|||.:.:||..|..:...|::|:.||.|:|.|..:.|.|::||
  Fly   607 SGIKRMLMLCCNLCGNSKILLLDEPGTSMDPAMRSNMWDLLRRERKGRCIIMATHNMNEAEVVAD 671

  Fly   689 RIAIMNDGQILCYGTLGYLKQLPFT--SYTLSCQMAPNSKADNLTDLVRLYMTTTTSPVFHGVDV 751
            :|.::.|.|::.|||.|:|.|:..|  ||.|.|..........:|:.:::............:.|
  Fly   672 QIVVLCDAQVIGYGTTGFLTQIAGTGSSYLLICTKMDTCIVAEVTNFLQIRFPDIKLHNEFSIYV 736

  Fly   752 SYKLPRSQIDRFPEFFQQLEENKKSLNVVSFGVSDSTLDGIYLSLDYGQGSSRLRGGADPGVNDK 816
            :|:||...:.::...|.:|||....||:....|...||..::|     |....:|
  Fly   737 TYELPTKYVQQYAALFLELEEALGELNLAEISVCAPTLGSVFL-----QMGEEMR---------- 786

  Fly   817 VEFGVQTDKAIRTKDRANNSLVRYQHQVDPPNETILNTKTPINPIEIWRPIDREKGSCMAQWQAM 881
                 |:...|.:.|..::         ..|..::||.   :...|:.....|.|  |..||:|:
  Fly   787 -----QSWNRISSFDLLSS---------PSPMLSLLNL---LPTFEVREDDGRVK--CCNQWRAI 832

  Fly   882 FIKKKNYT-----------ASRALIFILILIIPLFYYIIVLGTAASEKCAHRTDKQPVLPLSLDY 935
            ..||:.:|           |:..:|.:||:...:|.:::          .|...:..|..||:
  Fly   833 VEKKRLFTLRHQKFYCMIIATPIIICLLIISFSIFIFLV----------DHHLSELLVTDLSI-- 885

  Fly   936 YSYDDMIILLEVDKQLYKSEGEAYVQLVKEPATVESVDS--IFSHLLKAPPIIRRDIKRKYVCGA 998
              |...:.:::...:..:.|......::.:..||.|...  |..:||......:..::..::.||
  Fly   886 --YPKAVFVIDSPAEGNRFERHYMANVIGQGGTVRSTSGTPIDDYLLAEMESDQVKVQHTFLAGA 948

  Fly   999 SF-NNASTITAWFNSDAFEHSAPIALNLVYNALGKAVFEDQDFSILVNRGDLHDFIWLNNASSMR 1062
            :| :||::|.||.| :..:|.:.:::.|||.|:|:
  Fly   949 TFDSNANSIIAWSN-NKLKHGSALSMGLVYAAIGQ------------------------------ 982

  Fly  1063 RRYKRQNDPDYTDYSDYEIQEYDVVVKPNSSSTSGQHNKSNPGDDNIITVQMSI--IEAASTLYN 1125
                             |:.:.|:.:.          ||  |..|   |||.::  :..|||:.
  Fly   983 -----------------ELAKLDIRIV----------NK--PYQD---TVQQAVRGLIYASTIE- 1014

  Fly  1126 EKGKRKQLFGTLIIITAYIALCLSIFSIFVTKERVEHFKMQQEIYGVTLFYFWSTHFVGDFLIY- 1189
                    |..|:.  .|:.|..:||::....||....:.||...|::...:|.:|...|:..|
  Fly  1015 --------FAVLVF--HYLVLGTAIFAVLPIVERRSKVQHQQFSSGMSRSTYWLSHLSWDYCFYI 1069

  Fly  1190 AIYMGALTIAIYHFTIWYQVVVMLLLIGFACLPFVYLCSLLFSLPNIAFAGIFAILVMTG--GML 1252
            |:.:..:.:|.........|:|.||..||:.:.|.||..|:.:    .|..:|:|::...  |:|
  Fly  1070 AMILPLIVVAGITIGSVLPVIVQLLAFGFSAISFTYLLCLMSN----DFGKMFSIILYINMIGVL 1130

  Fly  1253 FSFMYMLTLITDVNFTTVFAIL---PMYVGTFGLFKCLAWREYCNREVLPPIEELDCKFGNCNVF 1314
            ..|::..:  ....:..:.::|   |.|....|:::.:....:..:: ||.:           :|
  Fly  1131 ALFIHPKS--PQTRYAVIESVLLVHPHYSLCCGMYEAIRMSTFSLKQ-LPYL-----------IF 1181

  Fly  1315 CACKPERTWMEVWLLMVHCLVWFIFLWFSNFGYEIGYRFKPKLSNRIWHNNEKHIRVLDE-ERRV 1378
            ...        .:|.:|      :|.|...   .:.|.||...:.:|:.:.:...:.:|: .||:
  Fly  1182 SGA--------AYLTIV------VFAWVPR---RLNYVFKSIRNEKIYPSYKDEDKEVDKMRRRL 1229

  Fly  1379 GLIPKYEHEDYPIIVDQVTKNYCRAKNAVQLVSFAIRPGDTFGLLGAQGAGKTSIFQMIAGETSM 1443
            ..:....:..:|:|:..::|.| .:..||:.::..:.|.:..||||..|:||:|||:||.|..|:
  Fly  1230 AYLTTAHYAFFPLILKNLSKRY-GSFVAVRSLTLDLNPFECVGLLGRNGSGKSSIFRMIVGMESI 1293

  Fly  1444 SHGNIYVRGHSLREHRNAAKMEVGFCPQGDNAPKYLTGRQLLRIHCLLHGVPKDHIKAVSEQMAI 1508
            :.|:|:::|:||:.....|...|||||:......::||:..||..||::|:.:::||::...:|.
  Fly  1294 TVGSIHIKGYSLKTRPKDASRHVGFCPRELMLLSFMTGKDALRFCCLINGIRREYIKSLVASLAE 1358

  Fly  1509 EFNFKDQLDRPIHTYSGGKKRKLNIALAIDSGSVLCLDDTNGSVDHATQRFIWRKLEAVKRSGRP 1573
            .|.....:::.|.|||.|.||||.||:...:.|::|||:....||...:..||..|:.:::.||.
  Fly  1359 CFELVPHMNKRISTYSNGTKRKLMIAMGTLAPSLMCLDEPTAGVDMHAKYEIWSILDGIRQGGRS 1423

  Fly  1574 VLLTTQSMEEANAVCSRVAFLVAGEMMFIGSLQQVR----------------------------- 1609
            :||||.::||...:|:.|..:..|.::..|||.:::
  Fly  1424 ILLTTHNLEECEFLCTNVGIMDHGSLLCYGSLSRLKHRFNMGIFVKVKMGTRAEMDDERDNWMQI 1488

  Fly  1610 -------SEVSNTIVIRLRV--------NP-------------------SDGKLKRRFQQLIADM 1640
                   ||:.:|:..|..:        ||                   |:..:::.::.|:.::
  Fly  1489 TMMPPNDSEMGSTVGARRMMLAHLLRHHNPPVEPVKKSRTSRAQPDTTNSELNMRKDYEALLQEL 1553

  Fly  1641 AELF----PLATLHE--ALETCLIYHININVTTLANLFYQMEKIRNEGLLEDYSITQVSLDEIY 1698
            .|:|    |.:|:.|  :....:.:.|.......:.:|..||.:::|..:..||::..:..:::
  Fly  1554 EEVFKKDHPYSTVSEKYSYRGMITFCIPRGQIKWSAIFEYMENLKDEMQILYYSVSHTTFQDVF 1617

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31213	NP_001262752.1	ABC2_membrane_3	32..>295	CDD:289468	74/296 (25%)
		ABC_subfamily_A	491..708	CDD:213230	88/216 (41%)
		drrA	498..796	CDD:130256	109/299 (36%)
		ABC2_membrane_3	<1132..1285	CDD:289468	37/158 (23%)
		CcmA	1391..1672	CDD:224054	90/349 (26%)
		ABC_subfamily_A	1391..1609	CDD:213230	76/217 (35%)
CG8908	NP_611464.3	ABC2_membrane_3	69..394	CDD:289468	89/342 (26%)
		LivG	471..686	CDD:223488	85/214 (40%)
		ABC_subfamily_A	474..691	CDD:213230	88/216 (41%)
		ABC2_membrane_3	845..1192	CDD:289468	86/466 (18%)
		NatA	1242..1461	CDD:226927	76/219 (35%)
		ABC_subfamily_A	1242..1459	CDD:213230	76/217 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451220
Domainoid	1	1.000	133	1.000	Domainoid score	I3135
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	228	1.000	Inparanoid score	I138
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D131191at2759
OrthoFinder	1	1.000	-	-		FOG0000051
OrthoInspector	1	1.000	-	-		otm51427
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR19229
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X215
	9	9.000