Protein Alignment CG31213 and Eato

DIOPT Version :9

• Sequence 1: NP_001262752.1
• Gene: CG31213 / 42382
• FlyBaseID: FBgn0051213
• Length: 1809
• Species: Drosophila melanogaster
• Sequence 2: NP_001036360.1
• Gene: Eato / 34783
• FlyBaseID: FBgn0028539
• Length: 1597
• Species: Drosophila melanogaster
• Alignment Length: 1903
• Identity: 407/1903 - (21%)
• Similarity: 735/1903 - (38%)
• Gaps: 550/1903 - (28%)

  Fly     1 MNRNLTYCQKYRLLLWKDIKLQLTNWVELVMIIFLS-ALMPIFFSIGTKVAKS------IFPPDI 58
            :.:||.|.|:..|.|     |.:.:....|:..:|. ::.|:...|....||:      ::.|..
  Fly    13 LRKNLLYLQRNLLPL-----LLICSGFAGVLTAYLHWSVKPVLHQINQFEAKNEMVLRELYFPGN 72

  Fly    59 EMEK------SPGPKSVNTSLFVDLYFTPNNGILEQLITQLANISEFKSVEVFDTNSELYLQLMI 117
            |::.      ||..:.:...|.|||      ||:.:.:.              ..|:...:||.:
  Fly    73 ELDYIYYSPISPNVEDIMDLLRVDL------GIIPERLR--------------PNNNSFEMQLEM 117

  Fly   118 NRNAIGIAFPSEWYDI--KSCPEVLNLTIF---MPLSIKRK------------DFKYFESGFLLL 165
            .:...|..|..:::.:  :........::.   |.:|.:::            |..|..||||.|
  Fly   118 EQQCRGSCFAIDFHRVPNRGSDRKFRYSLSSNQMRISPRKRFVNDEEIYHQIDDDDYIRSGFLSL 182

  Fly   166 QERISKIFIFFKNAGNGKIPRVLMNHFPYPSYVPNHYAESAKAMTYM-TLISFFLPCITIAKYVV 229
            |..:.|.::.::..  ||...|:::..|....:    :..:..:||. ||.|.....:.::.:||
  Fly   183 QHILDKQYMKYQEL--GKDFEVVVSSMPNMEVI----SMDSHRLTYFGTLCSILFNVVLLSSFVV 241

  Fly   230 AEKERHQKA------VLTAMGFSNSIHWLAWYTKSMLLLLLC-LLIMISIFSIGLIYEFSSLVC- 286
            ...|..|..      ::|.|.|.|.:.:       .|:..:| .|:||.:..:..:|:....:|
  Fly   242 PFVEEKQNGLKEFLNLVTPMSFLNGLTF-------FLIRFVCYTLLMIFVLVVAYLYKALGSICF 299

  Fly   287 --LMTIFLVYIHSLVLFAFFIS----SFFSRSLSAVVATILMY-------FSTALPFLIVGAENS 338
              :..:||:||.|.:.:|:.||    |.|...:..:...|:.|       ::|:|.| :..:.|:
  Fly   300 AYVAVLFLLYILSTMSYAYLISICFHSVFYAKIGGLAMLIIPYAFSFVRSWATSLAF-VCFSTNT 363

  Fly   339 SVAA----QTAASIGLNSALFYILDSVAVMEMQSVGAQWYTIDNTASSGYKLSIVGYMLIMISIS 399
            .:..    ||.::...|.. |..:|...|::..|         :|..|.|        ::::..|
  Fly   364 FLEGLDIFQTFSNKRKNRE-FGAVDVFRVIKSNS---------STMFSVY--------VVLVFQS 410

  Fly   400 WIELLICLYIEAVRTGEFEVPQPWSYPFQRRYWCPLRYGSSVFHQGALLPLAGKNSEGNLPAAHP 464
            ::..::..|:..|..|...:.:|..:
  Fly   411 FLYAMLYNYLGCVFPGPGGLKRPMFF--------------------------------------- 436

  Fly   465 TRQPIIYLDDRT----QENFQRVNISKKIGIEVRSLSKTFGFRN----VVKDLFFNVYENEITAL 521
                  :||.:|    |.|...........|.:..|.|.|....    :..:|...:...|||.|
  Fly   437 ------FLDPKTYMKRQRNEYTTTPRGTHAIIITELCKKFQTSKRDTLISDNLNMTINNKEITVL 495

  Fly   522 VGHKGSGKTTIIMMLCGILQPTTGTVLINGYDIVTEAKVA--KSSLGICPQHSVIFKGMSARDHI 584
            :||.|:||||::.|:.|::...:|.::     :.:|..||  :..:|.||||||....|:...|:
  Fly   496 LGHNGAGKTTMMNMIMGLVPKDSGKII-----VCSERDVASYRHLIGFCPQHSVFMSYMTCHQHL 555

  Fly   585 YFFSRVKGYNKTEAMMESNIYISKLGLVDSQKWDAMRLSPGNQRRLSLACALCAGSKVILCDEPS 649
            .||::::|..:::|...::..:.||||.|.:......||.|.:|||||..|:...:|:::.||||
  Fly   556 EFFAQLRGACRSDARDWADEKLKKLGLSDKRNEFGKNLSGGMKRRLSLGIAIAGNTKIVILDEPS 620

  Fly   650 SGLDPIGRHELMRFLQKEKHGRTILMTTQQLEEGEILADRIAIMNDGQILCYGT---------LG 705
            ||||...|.||...|...:..:.:|:||..:||.|:|.|.|.|:.:|::...|:         :|
  Fly   621 SGLDINSRRELWDILLNLRKEKAVLVTTHYMEEAEVLGDTICILANGKLQSIGSPLELKRKSGIG 685

  Fly   706 YLKQLPFTSYTLSCQMAPNSKADNLTDLVRLYMTTTTSPVFHGVD--VSYKLPRSQIDRFPEFFQ 768
            |..:|....:|        |:...:.:::..::  .|:.|.:.|:  |...||.:..:.|.:...
  Fly   686 YRLKLEINDFT--------SREVEIMEIIHHFV--PTARVLNVVNPTVYICLPYAYKNCFAQMLY 740

  Fly   769 QLEENKKSLNVVSFGVSDSTLDGIYLSLDYGQGSSRLRGGADPGVNDKVEFGVQTDKAIRTKDRA 833
            :||...|.|.:.:..::|::|:.::|..              .|..|:|:          |.|.:
  Fly   741 RLETESKELGIHTISMTDTSLEDVFLRC--------------AGEQDQVD----------TPDGS 781

  Fly   834 NNS---LVRYQHQVD-PPNETILNTKTPINPIEIWRPIDREKGSCMAQWQAMFIKKKNYTASRAL 894
            .|.   |..|:...| ||:..:...                       |.|:|.||..:.::..|
  Fly   782 RNDAPLLAHYKRLQDHPPHRGLFQL-----------------------WMAVFYKKWTFISNEWL 823

  Fly   895 IFILILIIPLFYYIIVLGTAASEKCAHRTDKQPVLPLSLDYYSYDDMIILLEVDKQLYKSEGEAY 959
            ..:::|.||   ::.|.|...........:.:..|||.|.                 ....|..|
  Fly   824 YTLIMLCIP---FVCVFGAILVMHAMSLVENEEALPLKLS-----------------QMGSGVIY 868

  Fly   960 V-----------QLVKEPATVESVDSIFSHLLKAPPI------IRRD-----------IKRKYVC 996
            |           |.:::...:..:.:...||..:..:      ::||           |...|..
  Fly   869 VHNPTGHHAHLEQQLRQQIELNGITAKTMHLRGSNDVKNESLDLQRDNLADFLEQVIGIIDMYGG 933

  Fly   997 GASFNNASTITAWFNSDAFEHSAPIALNLVYNA---LGKAVFEDQDFSILVNRGDLHDFIWLNNA 1058
            |...::..||..:::.:.: ||:...:|||.:|   ||:...|.....:.:.|     |:
  Fly   934 GRGTSDTPTIEIFYSGNRY-HSSVELINLVDSAMLKLGRPESEIDTTYVPIRR-----FV----- 987

  Fly  1059 SSMRRRYKRQNDPDYTDYSDYEIQEYDVVVKPNSSSTSGQHNKSNPGDDNIITVQMSIIEAASTL 1123
                           :|.|...::.|.|:|.                    |.:...:....|..
  Fly   988 ---------------SDISPSRLEYYAVIVP--------------------IGMFFFMFYFISLP 1017

  Fly  1124 YNEKGKR-KQL--------------FGTLIIITAYIALCLSIFSIFVTKERVEHFKMQQEIYG-- 1171
            :.|.... |||              |..||:    |.:|:::||:       :...|..|:|.
  Fly  1018 FREYANGFKQLQTMSRFTYWFAHFTFDMLIL----IFVCVALFSL-------QSLMMPSELYTTA 1071

  Fly  1172 ------VTLFYFWSTHFVGDFLIYAI---YMGALTIAIYHFTIWYQVVVMLLLIGFACLPFV--- 1224
                  :::|::..::..   ::||:   :....||:.|         ::|:||..|..|.:
  Fly  1072 ELKVIVLSIFFYGCSYLP---ILYALGNNFKSISTISTY---------LLLMLIVSAIAPLITSS 1124

  Fly  1225 -------------YLCSL-------LFSLPNIAF---------AGI------FAILVMTGGMLFS 1254
                         :||.|       .|.:.|..|         .|:      ||.....|.|:.:
  Fly  1125 NAAAMKLHETKIAFLCFLPDFNLNHQFRIINENFITRRHPALIKGLISQDTFFAYATAVGVMVMA 1189

  Fly  1255 FM-------YMLTLITDVNFTTVFAILPMYVGTFGLFKCLAW----REYCNREVLP--PIEELDC 1306
            |.       |:...|.|                 |:::   |    ::|.:...||  ||.|:|
  Fly  1190 FFTIVLEHKYLRRRIHD-----------------GIWE---WAFQRKKYNSTGTLPSTPISEID- 1233

  Fly  1307 KFGNCNVFCACKPERTWMEVWLLMVHCLVWFIFLWFSNFGYEIGYRFKPKLSNRIWHNNEKHIRV 1371
                   .||
  Fly  1234 -------DCA------------------------------------------------------- 1236

  Fly  1372 LDEERRVGLIPKYEHEDYPIIVDQVTKNYCRAKNAVQLVSFAIRPGDTFGLLGAQGAGKTSIFQM 1436
             .||:||..:.|....|:.:||..:.|.| ..|.||..||||...|:.|||||..||||||.|||
  Fly  1237 -REEKRVTDLIKDPLNDHSLIVHNLRKRY-GDKLAVDGVSFAAAQGECFGLLGVNGAGKTSTFQM 1299

  Fly  1437 IAGETSMSHGNIYVRGHSLREHRNAAKMEVGFCPQGDNAPKYLTGRQLLRIHCLLHGVP------ 1495
            ||....:..|.|.::|..:|||....:...|:|||.|...|::|..|.|....||.|:.
  Fly  1300 IAANLPLDGGTIRIKGADIREHELKYREYFGYCPQYDALNKFMTAEQCLYYMALLRGLSRRRTDG 1364

  Fly  1496 ----KDHIKAVSEQMAIEFNFKDQLDRPIHTYSGGKKRKLNIALA-IDSGSVLCLDDTNGSVDHA 1555
                |:|:|...|:|.:....|.|    :..||||.||||..|:| |.:.:::.||:....||..
  Fly  1365 PASCKEHVKYWLEKMHLTKYQKVQ----VRHYSGGTKRKLLAAMAMIGAPALVLLDEPTTGVDPI 1425

  Fly  1556 TQRFIWRKLEAVKRSGRPVLLTTQSMEEANAVCSRVAFLVAGEMMFIGSLQQVRSEVSNTIVIRL 1620
            ::||:|:.::..:...|.|:||:.||:|...:|:|:|.:..|:...:.::..::.....||.:::
  Fly  1426 SRRFLWQCIKDFQGKDRTVVLTSHSMDECEELCNRLAIMAHGKFKCLNNICALKRLSGFTIKLKM 1490

  Fly  1621 RVNPSDGKLKRRFQQLIADMAELFPLATLHEALETCLIYHINI--NVTTLANLFYQMEKI---RN 1680
            :   :|.:.:.....:...:...||...|.|:....|.|.::.  :|...:::|...|:.   |.
  Fly  1491 K---ADTETEMNVSTITGTLKSEFPGLELRESHAGTLTYFVSTQESVVLWSSVFKIAEEYLGDRL 1552

  Fly  1681 EGLLEDYSITQVSLDEIY 1698
            ..|:.|||:.:.:|::|:
  Fly  1553 SALVADYSVNECTLEDIF 1570

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31213	NP_001262752.1	ABC2_membrane_3	32..>295	CDD:289468	57/303 (19%)
		ABC_subfamily_A	491..708	CDD:213230	76/231 (33%)
		drrA	498..796	CDD:130256	91/314 (29%)
		ABC2_membrane_3	<1132..1285	CDD:289468	39/222 (18%)
		CcmA	1391..1672	CDD:224054	92/293 (31%)
		ABC_subfamily_A	1391..1609	CDD:213230	82/228 (36%)
Eato	NP_001036360.1	ABC2_membrane_3	<209..347	CDD:289468	32/148 (22%)
		CcmA	460..767	CDD:224054	92/321 (29%)
		ABC_subfamily_A	461..679	CDD:213230	74/222 (33%)
		ABC2_membrane_3	<937..1117	CDD:289468	43/248 (17%)
		ABC_subfamily_A	1255..1479	CDD:213230	82/228 (36%)
		drrA	1262..1573	CDD:130256	99/317 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451221
Domainoid	1	1.000	40	1.000	Domainoid score	I3722
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	228	1.000	Inparanoid score	I138
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D131191at2759
OrthoFinder	1	1.000	-	-		FOG0000051
OrthoInspector	1	1.000	-	-		otm51427
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR19229
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X215
	9	9.000