Protein Alignment CG31213 and CG1801

DIOPT Version :9

• Sequence 1: NP_001262752.1
• Gene: CG31213 / 42382
• FlyBaseID: FBgn0051213
• Length: 1809
• Species: Drosophila melanogaster
• Sequence 2: NP_728408.3
• Gene: CG1801 / 33104
• FlyBaseID: FBgn0031171
• Length: 1655
• Species: Drosophila melanogaster
• Alignment Length: 1881
• Identity: 378/1881 - (20%)
• Similarity: 680/1881 - (36%)
• Gaps: 474/1881 - (25%)

  Fly    10 KYRLLLWKDIKLQLTNWVELVMIIFLSALMP----IFFSIGTKVAKSIFPPDIE----MEKSPGP 66
            :..|.||:....::...|.:|::|||:.:..    ::.:...:..:||....::    :.:....
  Fly    14 RIELNLWRRTLFEIVALVIMVLVIFLNPIAHSKRLLYTTTENENEQSIVSHKLQDINILTRMADS 78

  Fly    67 KSVNTSLFVDLYFTPNNGILEQLITQLANISEFKSVEVFDTNSELYLQ---------LMIN--RN 120
            |...|...  |.|||......::...:|...|..|...:::.||:..|         ::.|  |:
  Fly    79 KREKTKYI--LAFTPETTFTSEVTKNVAKTLELSSTVGYESESEMQNQFDERTTLAGIVFNDLRD 141

  Fly   121 -------AIGIAFPSE-------------WYDIKSCPEVLNLTIFMPLSIKRKDFKYFESGFLLL 165
                   :|.|.||||             |  |..|...:|.........|::|. |...|||.|
  Fly   142 DGTPLTLSISIRFPSEFRTIAPFLTEDRLW--ITRCSGRINPGRDRAKHDKQQDI-YIREGFLQL 203

  Fly   166 QERISKIFIFFKNAGNGKIPRVLMNHFPYPSY-----------VPNHYAESAKAMTYMTLISFFL 219
            |.   :||:.:.:    ::.:.:::.:|.|:.           .|......|:..|::....:.|
  Fly   204 QH---QIFVEWYH----QLRKDIVSTYPEPNVEVYNILLKAADEPCSVMSVAQLPTFLYNFIYLL 261

  Fly   220 PCITIAKYVVAEKERHQKAVLTAMGFSNSIHWLAWYTKSMLLLLLCLLIMISIFSIGLIY----- 279
            |.:.|.:.|.|:.|..........|:|..:.|...:.  :|.|.:|:|        |:||
  Fly   262 PFLNIIRNVAAQVEDGVMVHQWHYGYSFGMQWGIKFL--VLFLRMCIL--------GVIYTIMLL 316

  Fly   280 ----------EFS-----SLVCLMTIFLVYIHSLVLFAFFISSFFSRSLSAVVATILMYFSTALP 329
                      |||     :.||.:|::.|   .:::....::..|:...:||:..::::......
  Fly   317 AFWGFGGREGEFSGTGTIAFVCFITLYTV---EIIITGMVVAKLFANPTNAVLFALMLWLFMYAA 378

  Fly   330 FLIVGAENSSVAAQTAASIGLNSALFYILDSVAVMEMQSVGAQWYTID---NTASSGYKLSIVGY 391
            |.|:......:.         ...:|:||.:....:|.      :::.   |.......::.:.:
  Fly   379 FCIILERYWDIH---------KYYVFFILVAFCNCQMH------FSMSLFRNCIEKPEMVNTIDF 428

  Fly   392 MLIM---ISISWIELLICLYIEAVRTGEFEVPQPWSYPFQRRYWCPLRYGSSVFHQGALLPLAGK 453
            :||.   ||.:.|..||.|.|:            |..|                  |..|.....
  Fly   429 VLIFTSAISSALIYFLILLAIQ------------WRMP------------------GTFLSRRIV 463

  Fly   454 NSEGNLPAAHPTRQ-----PIIYLDDRTQ-ENFQRVNISKKIGIEVRSLSKTF--GFRNVVKDLF 510
            |:       .|.:|     .|:||..... :||:..::.....:.:|.:|.:.  ..|.::|::.
  Fly   464 NN-------RPRKQQESDTTIMYLGRAPSFQNFEFGDVGSVELMRLRHVSTSHRDSERKILKNIS 521

  Fly   511 FNVYENEITALVGHKGSGKTTIIMMLCGILQPTTGTVLINGYDIVTEAKVAKSSLGICPQHSVIF 575
            ..:|..|:..::||.||||.|::.:|.|:..|..|.|.|.|.......:
  Fly   522 MRIYRGEVFVILGHIGSGKLTLLRILAGLKFPLRGNVYIMGNPFEPNGE---------------- 570

  Fly   576 KGMSARDHIYFFSRVKGYNKTEAMMESNIYISKLGL---------VDSQKWDAM----------- 620
                ||..:.|.....|.||...:.::..|..:|.|         ::.:||.|:
  Fly   571 ----ARRLVDFRFDEHGLNKHLTVEQTIDYHVRLKLSPSESDRYEIERRKWLAILDQHVESRGVR 631

  Fly   621 --RLSPGNQRRLSLACALCAGSKVILCDEPSSGLDPIGRHELMRFLQKEKHGRTILMTTQQLEEG 683
              :||.|:.:.::|.|.|...:.:|:.:||::.|...........:..||..|..::.|..:.|.
  Fly   632 IGKLSSGSMKLVALCCCLAGDTPIIILEEPTTQLTGREAQIFWSIVHAEKENRAFIIATYNVGEA 696

  Fly   684 EILADRIAIMNDGQILCYGTLGYLKQLPFTSYTLSCQMAPNSKADNLTDLVRLYMTTTTSPVFHG 748
            |.:||||.|::.|.:...||..:|:....:|..|.....|:.....:||.:..:|.........|
  Fly   697 EHVADRIGILSMGVLEASGTPFFLRSKFSSSVDLVIIKKPHVPDQPITDYINQFMQNIEPENEIG 761

  Fly   749 VDVSYKLPRSQIDRFPEFFQQLEENKKSLNVVSFGVSDSTLDGIYLSLDYGQGSSRLRGGADPGV 813
            ..::|:||.....|..:....||.::|.|.:.:..|..:.|..||::|   ..|.||:....|.|
  Fly   762 DSLTYRLPVIYRPRLQKLLIHLEIDRKMLGIENVRVVGAELSDIYMTL---VTSFRLQQQMIPDV 823

  Fly   814 NDKVEFGVQTDKAIRTKDRANNSLVRYQHQVDPPNETILNTKTPINPIEIWRPIDREKGSCMAQW 878
            ....::.|.:.|.: ||.|                                             .
  Fly   824 TQTFKYQVVSQKQL-TKQR---------------------------------------------M 842

  Fly   879 QAMFIKKKNYTASRALIFILILIIPLFYYIIVLGTAASEKCAHRTDKQPVLPLSLDYYSYDDMII 943
            :|||.||..:||..  ::.:|:|...|..|.::..                           :.:
  Fly   843 RAMFYKKMIHTAPN--VWPIIMIFTSFVLIAIIAR---------------------------LSV 878

  Fly   944 LLEVDKQLYKS------EGE---AYVQLVKEPATVESVDSIFSHLLKAPPIIRRDIKRKYVC--G 997
            ||::.|:...|      |.|   .|:..:|:...::...::..:..|:..:.|......:||  |
  Fly   879 LLDMPKERQNSIHIGFREPEDVVKYLPNLKDCGYIDIRSAVKVNKKKSVGVSRTFDDDSFVCEKG 943

  Fly   998 ASFNNA-----------------STITAWFNSDAFEHSAPIALNLVYNALGKAVFEDQDFSILVN 1045
            :..||.                 ..:..:.:.|.| ||||:.|||:.|.:
  Fly   944 SYRNNLRKKNELRSFGAVESDGDEHLNGYISQDMF-HSAPMMLNLLQNVI--------------- 992

  Fly  1046 RGDLHDFIWLNNASSMRRRYKRQNDPDYTDYSDYEIQEYDVVVKPNSSSTSGQHNKSNPGDDNII 1110
                           :|..|..|.|.              ||:..|....:....|.|..|:.|.
  Fly   993 ---------------LRLSYPMQTDL--------------VVLVENHPLPTQLSQKINVLDNKIA 1028

  Fly  1111 TVQMSIIEAASTLYNEKGKRKQLFGTLIIITAYIALCLSIFSIFVTKERVEHFKMQQEI------ 1169
            .:.:.                      :::...|.|.:|:|.|.:.:|.:...:..|.:
  Fly  1029 HIHVP----------------------LVVGCIIPLTVSVFVIPLVEEEIYDVRFLQHMAGLGLK 1071

  Fly  1170 --YGVTLFYFWSTHFVGDFLIYAI--YMGALTIAIYHFTIWYQVVVMLLLIGFACLPFVYLCSLL 1230
              :|:.||:.|.|.||...:|..|  .||......|...|   :||:|...|.|.||..||.|:.
  Fly  1072 VFWGINLFWDWFTFFVYSVIIVVIMSLMGIGGFGFYENAI---MVVLLTTFGLAALPLTYLVSMF 1133

  Fly  1231 FSLPNIAFAGIFAILVMTGGMLFSFMYMLTLITDV-NFTTVFAILPMYVGTFGLF---------- 1284
            .   |.:....|.:.|:..|:  |.:.:..:..|| |..|:|.........|.|.
  Fly  1134 V---NKSIVRAFLVSVLLQGV--SGLVLYIIYWDVANSNTIFFYAACMSPGFSLLDGVSNVYAQN 1193

  Fly  1285 --------KCLAWREYCN----REVLPPIEELDCKFGNCNVFCA--CKPERTWMEVWLLMVHCLV 1335
                    ||.| .:.|.    .||:|     :|||.....:.|  ..|...:|.:..|:...|:
  Fly  1194 LEQAICIDKCEA-TDSCTEENMNEVVP-----NCKFDTFFKWAAPGILPPILYMVLSALIFLMLI 1252

  Fly  1336 WFIFLWFSNFGYEIGYRFKPKLSNRIWHNNEKHIR-------------------VLDEERRVGLI 1381
            ::|.|                      |..||...                   |.|.::::...
  Fly  1253 FWIEL----------------------HRREKKFHTSRDLRKMRTATYPFDDGDVADVKQKIAEA 1295

  Fly  1382 PKYEHEDYPIIVDQVTKNYCRAKNAVQLVSFAIRPGDTFGLLGAQGAGKTSIFQMIAGETSMSHG 1446
            ...:.:....:||||......|...:..||||:....:.|:.|.:.:||:.:.:.:.|:...:.|
  Fly  1296 DNTKAKQSVFLVDQVEARVPAAGKRIHTVSFALNKYMSMGIFGPRNSGKSHLMRQLVGQRGFAFG 1360

  Fly  1447 NIYVRGHSLREHRNAAKMEVGFCPQGDNAPKYLTGRQLLRIHCLLHGVPKDHIKAVSEQMAIEFN 1511
            .|||||...:....:....:|:.||.......||.|:.:|:.|::.|||:..|......:.:..|
  Fly  1361 EIYVRGLDFKYDLESIHTYMGYSPQHRGLLNELTPREHIRLLCMIRGVPEAKIGEKMHDLCLMLN 1425

  Fly  1512 FKDQLDRPIHTYSGGKKRKLNIALAIDS-GSVLCLDDTNGSVDHATQRFIWRKLEAVKRSGRPVL 1575
            ....:.|.....:..|:.||.||||:.: ..:|.||:....:...|:|.||..|..::..|:.::
  Fly  1426 MTGWMHRKCSLLTAEKRHKLKIALALVAYNKILVLDEPTCGMPATTRREIWNILRYIRYCGKTII 1490

  Fly  1576 LTTQSMEEANAVCSRVAFLVAGEMMFIGSLQQVRSEVSNTIVIRLRVNPSDGKLKRRFQQLIADM 1640
            ..|....|...:...:......||:.|||||.:|.:.|:...:.:|:......|....:.|..|:
  Fly  1491 FATNDELECKILADFIILFQDSEMLAIGSLQYLRYKYSHGFYLEVRLIRDGATLAESEENLRKDV 1555

  Fly  1641 AELFPLAT-LHE------ALETCLIYHININVTTLANLFYQMEKIRNEGLLEDYSITQVSL 1694
            ..|..... ||.      .|.....:::.:.....:.|:..|||.:....:.||.|.|..:
  Fly  1556 ENLAKFVNFLHNRSELVGRLNNWFKFYVPVGHIVYSFLYGAMEKNKLRLNVSDYCIYQADM 1616

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31213	NP_001262752.1	ABC2_membrane_3	32..>295	CDD:289468	67/332 (20%)
		ABC_subfamily_A	491..708	CDD:213230	56/240 (23%)
		drrA	498..796	CDD:130256	74/321 (23%)
		ABC2_membrane_3	<1132..1285	CDD:289468	42/181 (23%)
		CcmA	1391..1672	CDD:224054	69/288 (24%)
		ABC_subfamily_A	1391..1609	CDD:213230	59/218 (27%)
CG1801	NP_728408.3	ABC2_membrane_3	<246..379	CDD:289468	28/145 (19%)
		ABC2_membrane_4	<293..448	CDD:289500	32/182 (18%)
		EcfA2	499..717	CDD:224047	55/237 (23%)
		P-loop_NTPase	500..721	CDD:304359	56/240 (23%)
		ABC2_membrane_3	<972..1254	CDD:289468	78/362 (22%)
		EcfA2	1307..1521	CDD:224047	57/213 (27%)
		P-loop_NTPase	1324..1524	CDD:304359	54/199 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449306
Domainoid	1	1.000	40	1.000	Domainoid score	I3722
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	228	1.000	Inparanoid score	I138
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D131191at2759
OrthoFinder	1	1.000	-	-		FOG0000051
OrthoInspector	1	1.000	-	-		otm51427
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR19229
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X215
	9	9.000