Protein Alignment CG31213 and Abca13

DIOPT Version :10

• Sequence 1: NP_732473.2
• Gene: CG31213 / 42382
• FlyBaseID: FBgn0051213
• Length: 1809
• Species: Drosophila melanogaster
• Sequence 2: NP_839990.2
• Gene: Abca13 / 268379
• MGIID: 2388707
• Length: 5034
• Species: Mus musculus
• Alignment Length: 1812
• Identity: 432/1812 - (23%)
• Similarity: 745/1812 - (41%)
• Gaps: 405/1812 - (22%)

  Fly    93 LANIS------EFKSVEVFDTNSELYLQLMINRNAI-GIAFPS--EWYDIKSCPEVL----NLTI 144
            |||:|      .|::||..||......:||...:.: .|.|.|  ....|:|.|..|    ..||
Mouse  3392 LANLSSCVVLDRFQAVETVDTLETKAHELMQQNSFLASIIFNSSLRHRHIRSAPHKLPPHVTYTI 3456

  Fly   145 -------------------FMPLSIKRKDFKYFESGFLLLQERISKIFIFFKNAGNGKIPRVLMN 190
                               |.|.::....||| ...|:.||:.|.:..|..:.......|.....
Mouse  3457 RTNVLYSMRTDMIKNPSWKFHPQNLPAGGFKY-NYIFVPLQDMIERAIIVVQTGQESLEPTTQAQ 3520

  Fly   191 HFPYPSYVPNHYAESAKAMTYMTLISFFLPCITIAKYVVA----------EKERHQKAVLTAMGF 245
            ..|||.:..:         .::..:.||.|.|.:..::||          |:|...:..:..||.
Mouse  3521 AAPYPCHTSD---------LFLNNVGFFFPLIMMLTWMVAVASMVRKLVYEREIQIEEYMRMMGL 3576

  Fly   246 SNSIHWLAWYTKSMLLLLLCLLIMISIFSIGLIYEFSSLVCLMTIFLVYIH------SLVLFAFF 304
            ..:||:|:|:.::|..|.|      |..::.:|.:.|.:......|:::::      |.|:.::|
Mouse  3577 HPTIHFLSWFLENMATLAL------SSAALAVILKMSGIFMHSDAFIIFLYLLDFGVSAVMMSYF 3635

  Fly   305 ISSFFSRSLSAVVATILMYFSTALPF--LIVGAENSSVAAQT----AASIGLNSALFYILDSVAV 363
            :|.||:::.:|.:.|.|.|..:.||:  |:|.....|.|.||    .::......:|:|    ..
Mouse  3636 LSVFFNQANTAALCTSLGYMISFLPYVVLLVLHNQLSFAIQTLLCLLSTTAFGQGVFFI----TF 3696

  Fly   364 MEMQSVGAQWYTIDNTAS-SGYKLSIVGYMLIMISI-----SWIELLICLYIEAVRTGEFEVPQP 422
            :|.|..|.||..:..... .|.....|.:|::..:|     .|       |...:..|.|.:.:|
Mouse  3697 LEGQEEGIQWGNMYRAPEPGGMTFGWVCWMILFDAILYFLGGW-------YFSNLVPGTFGLGKP 3754

  Fly   423 WSYPFQRRYW-----------CPLRYGSSVFHQ-----GALLPLAGKNSEGNLPAAHPTRQPIIY 471
            |.:||...||           |.|..|...|::     |    |:.:|..|.:...:|
Mouse  3755 WYFPFTASYWKSICGLMERRRCSLSSGLFFFNEDFGNKG----LSQQNGPGEMEGGNP------- 3808

  Fly   472 LDDRTQENFQRVNISKKIGIEVRSLSKTFGFRNV-VKDLFFNVYENEITALVGHKGSGKTTIIMM 535
                              |:.:.|::|.:....| |::|....:.::||||:|..|:||||||.|
Mouse  3809 ------------------GVALISVTKEYEDHKVAVQELTLTFHRDQITALLGTNGAGKTTIISM 3855

  Fly   536 LCGILQPTTGTVLINGYDIVTEAKVAKSSLGICPQHSVIFKGMSARDHIYFFSRVKG--YNKTEA 598
            |.|:..||:||:.|||.::.|:....:..||:|||..|:...::.|:|:..|:.:|.  :...|.
Mouse  3856 LMGLFPPTSGTITINGKNLQTDLSKVREELGVCPQQDVLLDNLTVREHLMLFASIKAPWWTTKEL 3920

  Fly   599 MMESNIYISKLGLVDSQKWDAMRLSPGNQRRLSLACALCAGSKVILCDEPSSGLDPIGRHELMRF 663
            ..:.|..:.::.|...|...|..||.|.:|:||:..|....||.::.||||||:||..|..|...
Mouse  3921 QQQVNKTLDEVELTQHQHKPAGVLSGGMKRKLSIGIAFMGMSKTVVLDEPSSGVDPCSRRSLWDI 3985

  Fly   664 LQKEKHGRTILMTTQQLEEGEILADRIAIMNDGQILCYGTLGYLKQLPFTSYTLSCQMAPN---- 724
            |.|.:.||||:.||..|:|.|:|:|.:|::..|::.||.....||:......||:....|:
Mouse  3986 LLKYREGRTIIFTTHHLDEAEMLSDHVAVLQQGRLRCYAPPADLKETYGQGLTLTLSKQPSILET 4050

  Fly   725 ---SKADNLTDLVRLYMTTTTSPVFHGVDVSYKLPRSQIDR--FPEFFQQLEENKKSLNVVSFGV 784
               .....:|.|:::|:.........|.:::|.:|: ..||  |....|.|::|.:.|::..:|:
Mouse  4051 QEPKDVARVTSLIQIYIPQAFLKDSCGGELTYTIPK-DADRTCFKGLCQALDQNLQHLHLTGYGI 4114

  Fly   785 SDSTLDGIYLSLDYGQGSSRLRGGADPGVNDKVEFGVQTDKAIRTKDRANNSLVRYQHQVDPPNE 849
            ||:||:.::|.|                                .:|....|.:...::|:|.||
Mouse  4115 SDTTLEEVFLML--------------------------------LQDTNKKSYITPDNKVEPQNE 4147

  Fly   850 TILNTKTPINPIEIWRP----IDREKGSC---MAQWQAMFIKKKNYTASRALIFILILIIPLFYY 907
            ..:...:|.|...:..|    :....|.|   :.|..|:..|:..:|..........|::|:.:.
Mouse  4148 RPVGPLSPHNVSPLSTPPEGALPEPIGGCQLLLGQAVALLRKRLLHTLRAWKSTTSDLLLPVLFV 4212

  Fly   908 IIVLGTAASEKCAHRTDKQPVLPLSLDYYSYDDMIILLEVDKQLYKSEGEAYVQLVKEPATVESV 972
            .:.:|...            |.||::                        .|..|...|...|:.
Mouse  4213 ALAMGLFM------------VQPLAI------------------------TYPPLKLTPGHYETA 4241

  Fly   973 DSIFSHLLKAPPIIRRDIKRKY-----VCGASFNNASTITAWFNSDAFEHSAPIALNLVYNALGK 1032
            ::.|.......|.:...:.||:     ||..:|...|  ::|...   .:|.|
Mouse  4242 ETYFFSSGNHGPDLTHVLLRKFRDQDPVCADAFRMNS--SSWHRD---PYSGP------------ 4289

  Fly  1033 AVFEDQDFSILVNRGDLHDFIWLNNASSMRRRYKRQNDPDYT--------DYSDYEIQEYDVV-- 1087
               |.||                 :...::...|....|..|        :.|.|:::||.:|
Mouse  4290 ---ESQD-----------------SCGCLKCPNKSAGAPSLTNCLGHTLLNLSGYDVEEYLLVPS 4334

  Fly  1088 VKPNSS--STSGQHNKSNPGD-DNIITVQMSIIEAASTLYNEKGKRK-----QLFGTLII----- 1139
            .||...  |..||    .|.| :::.|........|...||:||...     .....||:
Mouse  4335 AKPRLGGWSFGGQ----IPNDAEDVKTNTSKPRTLAKVWYNQKGFHSLPSYLNHLNNLILWHHLP 4395

  Fly  1140 ----------ITAY----------------------IALCLSI-FSIF-------VTKERVEHFK 1164
                      ||.|                      :|||:.: |||.       |.::||...|
Mouse  4396 ANAVDWRQYGITLYSHPYGGALLNEDRILESIRQCGVALCIVLGFSILSASIGSSVVRDRVTGAK 4460

  Fly  1165 MQQEIYGVTLFYFWSTHFVGDFLIYAI-------YMGALTIAIYHFTIWYQVVVMLL-LIGFACL 1221
            ..|.|.|:....:|..:|:.|.|.|.:       .:||..:..:.|........:|| |.|:|.:
Mouse  4461 RLQHISGLGHRTYWLINFLYDMLFYLVSVCLCVAVIGAFQLTAFTFRENLAATALLLALFGYAMI 4525

  Fly  1222 PFVYLCSLLFSLPNIAFAG------IFAILVMTGGMLFSFMYMLTLITDV-NFTTVFAILPMYVG 1279
            |::||.|.:||..::||..      ||.:..|   ::.:...:|.:|:.. |...::.:|.....
Mouse  4526 PWMYLMSRIFSSSDVAFISYISLNFIFGLCTM---LMTTMPRLLAIISKAQNLQKIYNVLKWAFT 4587

  Fly  1280 TFGLFKCLAWR--EYCNREVLPPIEELDCKFG--------NCN----VFCACKPERTWMEVWLLM 1330
            .|..| ||...  |.|..::.   .:|...||        ..|    :|.....:.|::.:..||
Mouse  4588 IFPQF-CLGQGLIELCYNQIK---YDLTHNFGIDSYVSPFEMNFLGWIFVELTLQGTFLLLLRLM 4648

  Fly  1331 VH--CLVWFIFLWFSNFGYEIGYRFKPKLSNRIWHNNEKHIRVLDEERRVGLIPKYEHEDYPIIV 1393
            :|  .|.|                  |: .:.:..:..|..:.:|.|.....:.:.......:::
Mouse  4649 LHGDLLRW------------------PR-DHSVLQDIVKPAKDIDVETEQMRVLEGRTGGDMMVL 4694

  Fly  1394 DQVTKNYCRA----KNAVQLVSFAIRPGDTFGLLGAQGAGKTSIFQMIAGETSMSHGNIYVR--G 1452
            ..::|:|...    ..||..:|..|..|:.|||||..||||::.|:::.|||..|.|...:|  .
Mouse  4695 CNLSKSYRSVFGGKTTAVHGISLGIPRGECFGLLGVNGAGKSTTFKILNGETPPSSGYTVIRTPQ 4759

  Fly  1453 HSLREHRNAAK--MEVGFCPQGDNAPKYLTGRQLLRIHCLLHGVPKDHIKAVSEQMAIEFNFKDQ 1515
            ..:.:..:|.|  :.:|:|||.|...:.|||.:.|:.:|.|.|:||.:|..|:..:....:.:..
Mouse  4760 GDMVDLASAGKAGILIGYCPQQDALDELLTGWEHLQYYCRLRGIPKQYIPEVAADLVRRLHLESH 4824

  Fly  1516 LDRPIHTYSGGKKRKLNIALA-IDSGSVLCLDDTNGSVDHATQRFIWRKLEAVKRSGRPVLLTTQ 1579
            :|:|:.|||||.:|||:.||| :....:|.||:.:..:|..::|::|:.:....|.|...:||:.
Mouse  4825 VDKPVATYSGGTRRKLSTALALVGKPDILLLDEPSSGMDPCSKRYLWQTITQEVRDGCAAVLTSH 4889

  Fly  1580 SMEEANAVCSRVAFLVAGEMMFIGSLQQVRSEVSNTIVIRLRVNPSDGKLKRRFQQLIADMAEL- 1643
            ||||..|:|:|:|.:|.|....:|..|.:::...:...:::.::....:     ...::|..:|
Mouse  4890 SMEECEALCTRLAIMVDGSFRCLGPPQHIKNRFGDGYTVKVWLHKEGSQ-----PSAVSDCLKLH 4949

  Fly  1644 FPLATLHEALETCLIYHININVTTLANLFYQMEKIRNEGLL--EDYSITQVSLDEIY 1698
            ||...........|.||:..:...||:||..:|  .|:.||  |.|||:|.:|::::
Mouse  4950 FPGIQFKGQRLNLLEYHVQKSWECLADLFKVLE--NNKSLLNIEHYSISQTTLEQVF 5004

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31213	NP_732473.2	rim_protein	<118..1698	CDD:130324	421/1779 (24%)
Abca13	NP_839990.2	rim_protein	1..>82	CDD:130324
		rim_protein	3036..5019	CDD:130324	432/1812 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	4135..4165		6/29 (21%)