DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31213 and Abcg4

DIOPT Version :9

Sequence 1:	NP_001262752.1	Gene:	CG31213 / 42382	FlyBaseID:	FBgn0051213	Length:	1809	Species:	Drosophila melanogaster
Sequence 2:	NP_620405.3	Gene:	Abcg4 / 192663	MGIID:	1890594	Length:	646	Species:	Mus musculus

Alignment Length:	271	Identity:	63/271 - (23%)
Similarity:	123/271 - (45%)	Gaps:	34/271 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   468 PIIYLDDRTQENF----QRV-NISKKIGIEVRSLSKTF-----------GFRNVVKDLFFNVYEN 516
            |::....:..||.    ||. ::.|:..:::..:..::           |::.::|.|.......
Mouse    31 PVLTTHLKKVENHITEAQRFSHLPKRSAVDIEFVELSYSVREGPCWRKRGYKTLLKCLSGKFCRR 95

  Fly   517 EITALVGHKGSGKTTIIMMLCGILQP-TTGTVLINGYDIVTEAKVAKSSLGICPQHSVIFKGMSA 580
            |:..::|..|:||:|.:.:|.|..:. ..|.:|:||..  .|.:..:.......|..::...::.
Mouse    96 ELIGIMGPSGAGKSTFMNILAGYRESGMKGQILVNGRP--RELRTFRKMSCYIMQDDMLLPHLTV 158

  Fly   581 RDHIYFFSRVKGYNKTEAMME--SNIYISKLGLVDSQKWDAMRLSPGNQRRLSLACALCAGSKVI 643
            .:.:...:.:|...|.|...|  :.| ::.|||:.........||.|.::||::|..|.....|:
Mouse   159 LEAMMVSANLKLSEKQEVKKELVTEI-LTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVM 222

  Fly   644 LCDEPSSGLDPIGRHELMRFLQKEKH-GRTILMTTQQ----LEEGEILADRIAIMNDGQILCYGT 703
            ..|||:||||.....:::..::...| |||::.|..|    |.|   :.|::.|::.||.:..|.
Mouse   223 FFDEPTSGLDSASCFQVVSLMKSLAHGGRTVICTIHQPSAKLFE---MFDKLYILSQGQCIFKGV 284

  Fly   704 ----LGYLKQL 710
                :.|||.|
Mouse   285 VTNLIPYLKGL 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31213	NP_001262752.1	ABC2_membrane_3	32..>295	CDD:289468
		ABC_subfamily_A	491..708	CDD:213230	54/239 (23%)
		drrA	498..796	CDD:130256	57/236 (24%)
		ABC2_membrane_3	<1132..1285	CDD:289468
		CcmA	1391..1672	CDD:224054
		ABC_subfamily_A	1391..1609	CDD:213230
Abcg4	NP_620405.3	3a01204	44..646	CDD:273361	60/258 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000