Protein Alignment CG31213 and abt-5

DIOPT Version :9

• Sequence 1: NP_001262752.1
• Gene: CG31213 / 42382
• FlyBaseID: FBgn0051213
• Length: 1809
• Species: Drosophila melanogaster
• Sequence 2: NP_001364572.1
• Gene: abt-5 / 173081
• WormBaseID: WBGene00000023
• Length: 1582
• Species: Caenorhabditis elegans
• Alignment Length: 1891
• Identity: 406/1891 - (21%)
• Similarity: 738/1891 - (39%)
• Gaps: 519/1891 - (27%)

  Fly    14 LLWKDIKLQLTN--W------VELVMIIFLSALMPIFFSIGTKVAKSIFPPDIEMEKSPGPKSVN 70
            ||.||:.|...:  |      :.|::|.|.:|:| |:       |||..|.|   .||.|| |::
 Worm     8 LLQKDVLLMRRSKVWTGFEVAIPLILIAFPAAVM-IY-------AKSQAPED---AKSSGP-SID 60

  Fly    71 TSLFVDLYF--------TPNNGILEQLITQLANISEFKSVEVFDTNSELYL------QLMINRNA 121
            ..|..:.:.        .|:.|:  |.:..:.|...:..:...:|.:.|.|      :|.|.
 Worm    61 MMLSTESFHPTVSSTCQDPSYGV--QTVNNVENYWNYSPMRWDNTTNSLDLAKNPARKLFIK--- 120

  Fly   122 IGIAFPSEWYDIKSCPEVLNL-------TIFMPLSIKRKDFKYFESGFLLLQERISKIFIFFKNA 179
                      |:::|.:::.:       |:.:| :|.|:.:.:....:.:     :||.......
 Worm   121 ----------DVRACKKIVYIVEDKYKTTMVLP-AIGRRSYNFRSYNYYM-----NKIMFGLSQR 169

  Fly   180 GNGKIPRVLMNHFPYPSYVPNHYAESAKAMTYMTL--ISFFLPCITIAKYVVAEKERHQKAVLTA 242
            .|.  ...::.:|....|...::.||.....:..|  :...:|.|::|:.:|.||. ..|..||.
 Worm   170 ANN--TSSIIENFDIKLYSITNFEESGFGQNFGLLFAVCMLMPVISVARALVVEKS-SVKPYLTT 231

  Fly   243 MGFSNSIHWLAWYTKSMLLLLLCLLIMISIFSIGLIYEFSSLVC----LMTIFLVYIHSLVLFAF 303
            :|..   .|: :|.:..|..::....:|::.|  .:|.||...|    |..||:...| .|.|:.
 Worm   232 IGLP---LWM-FYLEHFLFGVIKNTFLITLLS--TLYIFSMDNCPTYVLAGIFMYTCH-CVSFSI 289

  Fly   304 FISS---FFSRSLSAVV-----ATILMYFSTALPF----------------LIVGAENSSVAAQT 344
            ..:|   |..|.:..:|     ..|.|:.|....|                |.|.|        |
 Worm   290 LCTSILPFGKRIVEGMVIIWITLIIAMHLSLEFEFDWLFWVPLLNPNYSLKLFVDA--------T 346

  Fly   345 AASIGLN----SALF----YILDSVAVMEMQSVGAQWYTIDNTASSGYKLSIVGYMLIMISISWI 401
            ..:.|.|    ||||    ..|.|.||                           |..||||.:.:
 Worm   347 FLASGPNGTPTSALFSSKKKTLQSAAV---------------------------YFGIMISCTVV 384

  Fly   402 ELLICLYIEAVRTGEFEVPQPWSYPFQRRYWCPLRYGSSVFHQGALLPLAGKNSEGNLPAAHPTR 466
            .|:..:::|.:.|..       .:...:|:|..|.:..            ||.|:
 Worm   385 MLVAAIFMEKLYTFV-------GHAIFKRFWRILGFSK------------GKRSK---------- 420

  Fly   467 QPIIYLDDRTQENFQRVNI-----------SKKIGIEVRSLSKTF-GFRNVVKDLFFNVYENEIT 519
                 :::|......|..|           |....||:..|.|.: .....|..|.......:::
 Worm   421 -----IEERGDGVEDRSTILQCKETVEGRGSAIADIELSGLVKVYQNGEKAVNGLSLRAIRGQVS 480

  Fly   520 ALVGHKGSGKTTIIMMLCGILQPTTGTVLINGYDIVTEAKVAKSSLGICPQHSVIFKGMSARDHI 584
            .|:||.|.||:|...|:.|:.|.|.|.|:|.|.|.......|:..:|.|||::.|:..::..:|:
 Worm   481 ILLGHNGCGKSTTFGMITGMHQATEGKVMIGGIDANANRAEARELIGYCPQYNPIYDELTVWEHL 545

  Fly   585 YFFSRVKGYN-KTEAMMESNIYISKLGLVDSQKWDAMRLSPGNQRRLSLACALCAGSKVILCDEP 648
            ...:.:||.: .::..|::...:.::.|.|.:...|..||.|.:|:|.:..|:..||:|||.|||
 Worm   546 RLVNALKGRSGGSDFKMDAESLLKQIELTDKRNTLAKNLSGGMKRKLCVCMAMIGGSRVILLDEP 610

  Fly   649 SSGLDPIGRHELMRFLQKEKHGRTILMTTQQLEEGEILADRIAIMNDGQILCYGTLGYLKQ---- 709
            ::|:||..|.::...|...|..||||:||..::|.|.|.|.|.:|:.|::...|:..||||
 Worm   611 TAGMDPSARIDVQNMLALVKADRTILLTTHYMDEAEKLGDWIFVMSHGKMAASGSKHYLKQKYGG 675

  Fly   710 ---LPFTSYTLSCQMAPNSKADNLTDLVRLYMTTTTSPVFHGVDVSYKLPRSQIDRFPEF----- 766
               |.....::...|.|....:...|:.:...:|.......|..:...:..::..|.|..
 Worm   676 GMLLTLVFKSVHDPMRPRKSYETAYDVCKTVCSTALVKDERGQMIEISILETEKSRLPTLLKILE 740

  Fly   767 -----------FQQLE----ENKKSLNVVSFGVSDSTLDGIYLSLDYGQGSSRLRGGADPGVNDK 816
                       ||.||    |..::|.:.:.|||.|:|:.:::.:  |.....:..|.  ||:.|
 Worm   741 SVMEEDYNNPEFQALEPDIQEKCRTLELATIGVSMSSLEQVFIKI--GDECDDIMNGT--GVDKK 801

  Fly   817 VEFGVQTDKAIRTKDRANNSLVRYQHQVDPPNETILNTKTPINPIEIWRPIDREKGSCMAQWQAM 881
            .|           :....::||:|                     :|.:|........|..| |:
 Worm   802 TE-----------RQEKFSTLVQY---------------------KIQQPKQGFSKLMMVVW-AL 833

  Fly   882 FIKKKNYTASRALIFILILIIPLFYYIIVLGTAASEKCAHRTDKQPVLPLSLDYYSYDDMIILLE 946
            ..|:..|.....:...|.:|:||                          |:|..::.
 Worm   834 LQKRAYYLYRNPVQITLQIILPL--------------------------LTLWLFAV-------- 864

  Fly   947 VDKQLYKSEGEAYVQLVKEPATVESVDSIFSHLLKAPPIIRRDIKRKYVCGASFNNASTITAWFN 1011
                       .:::|..:|..:..::|                                   |:
 Worm   865 -----------PFLRLEPKPPKLSDIES-----------------------------------FD 883

  Fly  1012 SDAFEHSAPIALNLVYNALGKAVFEDQDFSILVNRGDLHDFIWLNNASSMRRRYKRQNDPDYTDY 1076
            ...:.||. :.|.|          |:::...|.|        :||:.|:.     ......|.|:
 Worm   884 PSQYPHST-VLLQL----------ENENDDRLAN--------YLNSFSNF-----EVVKVGYNDH 924

  Fly  1077 SDYEIQEYD-------VVVKPNSSSTSGQHNKSNPGDDNIITVQMSIIEAASTLY---------- 1124
            ..|.:::|.       .:||.|....| :..|.:.||.| ..:.|:||  ||.:|
 Worm   925 YGYLVKKYSQVFKTLGFIVKVNKKGDS-KFYKISQGDKN-AAILMNII--ASAMYLRDPSVTKLP 985

  Fly  1125 ----------NEKGKRKQLFGTLIIITAYIALCLS-IF---SIFVTKERVEHFKMQQEIYGVTLF 1175
                      :.|.|.:.|....:....:..|.|: ||   ::::.:|::..|..||.:.|::..
 Worm   986 HVTSRVIWMNDPKIKYEGLASFFLFENIFFLLVLAGIFIQSTVYLIEEKICKFAHQQYLTGLSTI 1050

  Fly  1176 YFWSTHFVGDFLIYAIYMGALTIA-IYHFTIW----YQVVVMLLLIGFACLPFVYLCSLLFSLPN 1235
            .:|...|:.|||::..:: ..||. :..|.:.    :::||:...:.|...|.|||.|.|.:.|.
 Worm  1051 AYWGVVFLWDFLLFTFFL-LYTIGFLISFGVLQGHIHEIVVIFYGLLFYFAPLVYLTSALINTPT 1114

  Fly  1236 IAFAGIFAILVMTGGMLFSFMYMLTLITDVNFTTVFAILPMYVGTFGLFKCLAWREYCNREVL-- 1298
                        .|..|   :||                         |.|:.|..|.....|
 Worm  1115 ------------RGNFL---LYM-------------------------FCCIPWLAYSIVSELHN 1139

  Fly  1299 -PPIEEL--DCKFGNCNVFCACKPERTWMEVWLLMVHCL----------------VW-------- 1336
             |||::.  :.::|    |....|...:: ..|:.:..|                :|
 Worm  1140 FPPIQKYSDEIEYG----FRIFNPSIGFL-AGLMKIAALNYPKSGLDKHFEHLTNLWTYEGIFFE 1199

  Fly  1337 FIFLWFSNFGYEI----------------GYRFKPKLSNRIWHNNEKHIRVLDEERRVGLIPKYE 1385
            .:||:|......|                |.|.:.:...|..:...:..:.:.||.:  |:.:.:
 Worm  1200 LMFLFFGGIFLTILLGCATLKPFRRACFRGTRRRSQPRERKRYKGIESCKAVKEEEQ--LVQEVD 1262

  Fly  1386 HEDYPIIVDQVTKNYCRAKNAVQLVSFAIRPGDTFGLLGAQGAGKTSIFQMIAGETSMSHGNIYV 1450
            ..:..:::|.:.|::.:.: ||..:|.::...:.||:|||.|||||:.|.:|.|.|..:.|:..:
 Worm  1263 KNETVLVIDGLVKDFGKFR-AVNDLSISVGHEECFGMLGANGAGKTTTFDIITGLTMPTGGSATI 1326

  Fly  1451 RGHSLREHRNAAKMEVGFCPQGDNAPKYLTGRQLLRIHCLLHGVP--KDHIKAVSEQMAI-EFNF 1512
            .||.:.|     .:.:|:|||.|...:.::.||.|||...|.|.|  |:.::.|.:.:.: :|.:
 Worm  1327 DGHDITE-----TIHIGYCPQFDAMLQQISCRQTLRIMAKLQGYPNVKEVVELVLDCVGMSDFGY 1386

  Fly  1513 KDQLDRPIHTYSGGKKRKLNIALAIDS-GSVLCLDDTNGSVDHATQRFIWRKLEAVKRSGR-PVL 1575
            |     .:...|||:|||:::.:|:.| .:.:.||:....:|...:|.||..:..::...: .::
 Worm  1387 K-----LVKNCSGGQKRKISVGIALMSRATCIILDEPTAGIDPRARREIWDIIHEMREQAKCSIV 1446

  Fly  1576 LTTQSMEEANAVCSRVAFLVAGEMMFIGSLQQVRSEVSNTIVIRLRVNPSDGKLKRRFQQLIADM 1640
            ||:.||||..|:|:|:..|..|||:.:|:.|.::|:..||.::.|.:|..:.     .:.:...:
 Worm  1447 LTSHSMEECEALCTRIGILRKGEMIALGTSQSLKSQYGNTYMMTLILNSLED-----LESVCVIV 1506

  Fly  1641 AELFP---LATLHEALETCLIYHI-NINVTTLANLFYQMEKIRNEGLLEDYSITQVSLDEIY-RI 1700
            :|..|   |.|...:|.|.:::.: .......:..:.|:|.:..:...:||.:||.||::.: |:
 Worm  1507 SEEMPDAVLKTPESSLTTSIVWELPKSKSDKWSEKYNQVEVLAKKANAKDYMLTQASLEDTFIRL 1571

  Fly  1701 LNDEED 1706
            :..||:
 Worm  1572 ITTEEE 1577

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31213	NP_001262752.1	ABC2_membrane_3	32..>295	CDD:289468	61/289 (21%)
		ABC_subfamily_A	491..708	CDD:213230	70/218 (32%)
		drrA	498..796	CDD:130256	89/326 (27%)
		ABC2_membrane_3	<1132..1285	CDD:289468	32/161 (20%)
		CcmA	1391..1672	CDD:224054	80/289 (28%)
		ABC_subfamily_A	1391..1609	CDD:213230	69/222 (31%)
abt-5	NP_001364572.1	rim_protein	<419..1569	CDD:130324	297/1373 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160160142
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53524
OrthoDB	1	1.010	-	-		D131191at2759
OrthoFinder	1	1.000	-	-		FOG0000051
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19229
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.960