DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31213 and LOC101883122

DIOPT Version :9

Sequence 1:	NP_001262752.1	Gene:	CG31213 / 42382	FlyBaseID:	FBgn0051213	Length:	1809	Species:	Drosophila melanogaster
Sequence 2:	XP_021333309.1	Gene:	LOC101883122 / 101883122	-ID:	-	Length:	2391	Species:	Danio rerio

Alignment Length:	1414	Identity:	349/1414 - (24%)
Similarity:	577/1414 - (40%)	Gaps:	322/1414 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 QLITQLA---NISEFKSV--EVFDTNSELYLQLMINRNAIGIAF-----PSEWYDIKSCPEVLNL 142
            |.:||:.   ::.:|.||  |....|..|.| |.::|...|:.|     ||:    ...|..:..
Zfish   423 QQLTQILKCFDLDKFSSVSTEALLVNQALAL-LDLDRFWAGLVFTDLGDPSD----PQPPTHIRY 482

  Fly   143 TIFMPL-------SIKRK------------DFKYFESGFLLLQERISKIFIFFKNAGNGKIPRVL 188
            .|.|.:       .:|.:            |.:|...||:.||:.:.:..|..: .|..:...|.
Zfish   483 KIRMDVQDTERTDKLKERSWSPTARDNPLNDLRYVRGGFVYLQDMVDRAIIKLQ-TGVQQTLGVY 546

  Fly   189 MNHFPYPSYVPNHYAESAKAMTYMTLISFFLPCIT-IAKYVVAEKERHQKAVLTAMGFSNSIHWL 252
            ....|||.|:.:.:..:...|..|.|:..|...:: |.|.:|.||||..|.||...|.|||...|
Zfish   547 AQQMPYPCYMDDAFVSAIGTMLPMFLVLAFNYSVSEIIKGLVLEKERRLKEVLRVSGVSNSTIRL 611

  Fly   253 AWYTKSMLLLLL-CLLIMISIFSIGLIYEFSSLVCLMTIFLVYIHSLVLFAFFISSFFSRSLSAV 316
            .|:.::|:||:: |.||.:.: ..|.:..:|....:....||:..:.|:..||||.||||:..|.
Zfish   612 CWFAENMILLMVPCALISVMV-KYGKVLRYSDPSVIFVFLLVFCLATVMQCFFISVFFSRANLAA 675

  Fly   317 VATILMYFSTALPFLIVGA--ENSSVAAQTAASIGLNSALFYILDSVAVMEMQSVGAQWYTIDNT 379
            ....|:||...||.::..|  :.....|:.|.|:....|..|..::.:..|.|.||.||..|.::
Zfish   676 ACGGLLYFLLYLPHVLCYAWRDVLGFGAKIATSLLSCVAFGYGCENFSTYEAQGVGIQWSNIRSS 740

  Fly   380 ASSGYKLSIVGYMLIMISISWIELLICLYIEAVRTGEFEVPQPWSYPFQRRYWCPLRYGSSVFHQ 444
            .....:.|.:..:.:|:..:.|...:..|||.|..|::.:.:||.:||...|||..|.||.
Zfish   741 PQDNDRYSFIVSIFMMLFDALIYWTLTWYIENVYPGQYGIAKPWYFPFTSSYWCGSRVGSD---- 801

  Fly   445 GALLPLAGKNSEGNLPAAHPTRQPIIYLDDRTQENF-QRVNISKKIGIEVRSLSKTF--GFRNVV 506
                             .||.    :..|...|..| ::.....|.|:.:|:|.|.:  |.:..|
Zfish   802 -----------------GHPD----LLQDLENQSGFLEKPPSGLKPGVCIRNLVKVYKTGNKLAV 845

  Fly   507 KDLFFNVYENEITALVGHKGSGKTTIIMMLCGILQPTTGTVLINGYDIVTEAKVAKSSLGICPQH 571
            ..|..:.|::.||:.:||.|:||||.:.:|.|:..||:||..||||||.|:....:..||:||||
Zfish   846 DGLSLDFYQDHITSFLGHNGAGKTTTMSILTGLFAPTSGTAYINGYDIRTDMDCIRKQLGMCPQH 910

  Fly   572 SVIFKGMSARDHIYFFSRVKGYNKTEAMMESNIYISKLGLVDSQKWDAMRLSPGNQRRLSLACAL 636
            :|:|..::..:||||::|:||.:..|...|.:..|..:||...:|..|..||.|.||:||:|.|.
Zfish   911 NVLFDDLTVEEHIYFYARLKGRSSKEVKKEIDQMIKDVGLPHKRKDLAKNLSGGMQRKLSVAIAF 975

  Fly   637 CAGSKVILCDEPSSGLDPIGRHELMRFLQKEKHGRTILMTTQQLEEGEILADRIAIMNDGQILCY 701
            ..||.|::.|||::|:||..|..:...|.|.|.||||:::|..::|.:||.||:||::.|::.|.
Zfish   976 VGGSNVVILDEPTAGVDPYARRGIWELLLKYKQGRTIILSTHHMDEADILGDRVAIISHGRVQCC 1040

  Fly   702 GTLGYLKQLPFTSYTLSCQMAPNSKA------------------------------DNLTDLVRL 736
            |:..:||:.....|.|:...|...:|                              .:::|:.||
Zfish  1041 GSSLFLKKTYGRGYYLTIARANQERAPAQCVPSPEEFDQSSLDEGICSDSISSLDPPDVSDVSRL 1105

  Fly   737 YMTTTTSPVF---HGVDVSYKLPRSQIDR--FPEFFQQLEENKKSLNVVSFGVSDSTLDGIYLSL 796
            .........|   .|.::.|.||.|....  |...|::|:..|.:|.|.|:|:||::|:.|:|.:
Zfish  1106 VRRHVPEAEFLEAVGQELVYVLPYSGATNGSFATLFKELDLEKNTLGVTSYGISDTSLEEIFLKV 1170

  Fly   797 DYGQG---SSRLRGGADPGVNDKVEFGVQTDKAIRTKDR---ANNSLVRYQHQVDPPNETILNTK 855
            ....|   .|..:....|..:.::........|:..:|.   .|.:.||:..:|:..:..:....
Zfish  1171 AEDTGVDVESHDKPKQKPRSSSRISGKQSISSALECRDAKTVKNEAKVRFASRVEDTHRPMCANG 1235

  Fly   856 TPINPIEIWRPIDREKGSCMAQWQAMFIKKKNYTASRALIFILILIIPLFYYIIVLGTAASEKCA 920
            ...:.|..|..|.:       |:.|:|||:.::........|..:::|.|:..:.|..:.
Zfish  1236 KGSDVINGWSLIRQ-------QFLALFIKRFHHARRSRKGIIAQVVMPAFFVCLALIFSL----- 1288

  Fly   921 HRTDKQPVLPLSLDYYSYDDMIILLEVDKQLYKS--------EGEAYVQLVK------------- 964
                   ::|...:|.|       ||:...:|.:        :|...||:.|
Zfish  1289 -------IVPPFNEYPS-------LELQPWMYGAPQNTFYSFDGPGVVQVEKVTNALLNSPGFGT 1339

  Fly   965 ----------------------EPATVESVDSIFSH----------------------LLKAPP- 984
                                  .||...|:..||..                      |...||
Zfish  1340 RCMSTNPIPRLPCVSTGSTNWFTPAVDPSISDIFDKGNWTMQNPSPACQCSTAERSFMLPDCPPG 1404

  Fly   985 -------------------IIRRDI------------KRKY----VCGASFN---NASTIT---- 1007
                               :..|::            |.:|    |.|.:..   |.|.||
Zfish  1405 AGGLPPPQRTQNTTDTLQNVTGRNMTDFLLKTYQKSGKIRYGGFSVGGVNSQVRLNESDITTLVS 1469

  Fly  1008 ---AWFNSDAFEHSAPI--ALNLVYNALG-----KAVFEDQDFSILVNRGDLHDFIWLNNAS--S 1060
               :.||...|:.|..|  |:.|....||     |..|.:..:..||:        :||.||  :
Zfish  1470 DLRSVFNVSQFKQSEDIFQAIRLFLLELGTRDNMKVWFYNPGWHSLVS--------FLNVASNGA 1526

  Fly  1061 MRRRYKRQNDPDYTDYSDYEIQEYDVVVKPNSSSTSGQHNKSNPGDDNIITVQMSIIEAASTLYN 1125
            :|........|:     ||.|..::..:                   |:...|:|....||:
Zfish  1527 LRGNLPAGRRPE-----DYGITTFNHPL-------------------NLTREQLSTAALASS--- 1564

  Fly  1126 EKGKRKQLFGTLIIITAYIALCLSI----FSIFVTKERVEHFKMQQEIYGVTLFYFWSTHFVGDF 1186
                     .|.:::...:...:|.    |.:|:.:|||...|..|.:.||....:|..:|..|.
Zfish  1565 ---------STDVVVAICVIFAMSFIPASFVLFLIQERVTKAKHLQFVSGVNPTIYWLANFAWDM 1620

  Fly  1187 LIYAIYMGALTIAIYHFTIWYQ-----------VVVMLLLIGFACLPFVYLCSLLFSLPNIAFAG 1240
            ..|.:   ...|.|..|..:.|           ::::|.|.|::..|.:|..|.:||:|:.|:..
Zfish  1621 CNYIV---PCVIVIIIFLCFQQKSYVSPPNLPALILLLALYGWSITPMMYPFSFVFSVPSTAYVV 1682

  Fly  1241 IFAILVMTG--GMLFSFMYMLTLITDVNFTTVFAILPMYVGTFGLFKCL 1287
            :..|.:..|  |.:.:|  ::.|..|.|.|.:..|:...:..|..| ||
Zfish  1683 LTCINLFIGINGSVATF--VMELFDDPNITRINDIVKQALLVFPHF-CL 1728

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31213	NP_001262752.1	ABC2_membrane_3	32..>295	CDD:289468	63/237 (27%)
		ABC_subfamily_A	491..708	CDD:213230	88/218 (40%)
		drrA	498..796	CDD:130256	114/334 (34%)
		ABC2_membrane_3	<1132..1285	CDD:289468	39/169 (23%)
		CcmA	1391..1672	CDD:224054
		ABC_subfamily_A	1391..1609	CDD:213230
LOC101883122	XP_021333309.1	AAA	1..1833	CDD:333001	349/1414 (25%)
LOC101883122	XP_021333309.1	AAA	1835..>2372	CDD:333001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D131191at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010