Protein Alignment CG31213 and abca10

DIOPT Version :9

• Sequence 1: NP_001262752.1
• Gene: CG31213 / 42382
• FlyBaseID: FBgn0051213
• Length: 1809
• Species: Drosophila melanogaster
• Sequence 2: XP_031750511.1
• Gene: abca10 / 100485734
• XenbaseID: XB-GENE-6464279
• Length: 1610
• Species: Xenopus tropicalis
• Alignment Length: 1850
• Identity: 431/1850 - (23%)
• Similarity: 777/1850 - (42%)
• Gaps: 416/1850 - (22%)

  Fly    14 LLWKDIKLQ-------LTNWVE---LVMIIFLSALMPIF----------------------FSIG 46
            |.||::.|:       ...|::   .|.::||:..:.::                      .|:|
 Frog    18 LFWKNLLLKWRRKWHSTLEWLQNLAFVFLMFLTVAIELYGPTSDIDLSPAWVLGRLDAFNNLSVG 82

  Fly    47 ------------TKVAKSIFPPDIEMEKSPGPKSVNTSLFVDLYFTPNNGILEQLITQLANISEF 99
                        .||||.|..|||::::           |.|         .|:||..::|:|..
 Frog    83 YVHTTSTSRDIMEKVAKGIIVPDIKVQE-----------FAD---------EEELIEAVSNMSMV 127

  Fly   100 KSVEVFDTNSELYLQLMINRNAIGIAFPSEWY--------DIKSCPEVLNLTIFMPLSIKRKDFK 156
            ....|.:.:..:..||...::      |::::        |:..|    |.|.
 Frog   128 AVTFVDEFSYHIRYQLPKRKH------PNDYFAYMGNCGDDLSYC----NPTY------------ 170

  Fly   157 YFESGFLLLQERISKIFIFFKNAGNGKIPRVLMNHFPYPSYVPNHYA-----------ESAKAMT 210
            |:..|||.||..|....|           .:..||     .|.|:.|           .|.|.:.
 Frog   171 YWSEGFLSLQASIDSAII-----------DLTSNH-----SVWNNMASIVAIKMKSAERSYKVLA 219

  Fly   211 YMTLISFFLP-CITIAKYVVAE---KERHQ-KAVLTAMGFSNSIHWLAWYTKSMLLLLLCLLIMI 270
            ::....|.:| |.....|::::   :||:: |..|..|...:...||:|.     ||..|.:.::
 Frog   220 HVASFIFVMPMCYVSLMYLLSQYVTRERYEMKETLRLMRLQDLAFWLSWG-----LLYSCYVFIV 279

  Fly   271 ----SIFSIGLIYEFSSLVCLMTIFLVYIHSLVLFAFFISSFFSRSLSAVVA----TILMYFSTA 327
                ::.:...::..||...:|.:|.:|..:|:.|.|.:|:.|....:..:|    |:|:   :|
 Frog   280 ANLMTLVTKPFVFITSSYGIIMFMFFLYGVALMSFTFMLSALFRNPRATAIAGFFITLLL---SA 341

  Fly   328 LPFLIVGAENS-------SVAAQTAASIGLNSALFYILDSVAVMEMQSVGAQWYTIDNTASSGYK 385
            |..:::.....       |:..|.|.::|:..::.        ||....|.  |..|.|..|.:.
 Frog   342 LGLILLSKHVPKSVEVLLSIFPQFAFAVGITQSVH--------MENDQEGV--YFSDLTGGSSHM 396

  Fly   386 LSIVGYMLIMISISWIELLICLYIEAVRTGEFEVPQPWSYPFQRRYW-----CPLRYGSSVFHQG 445
            ||.. ..|::.|:.::.|  .||.|.|...:..|.....:..:..||     .||.
 Frog   397 LSCF-ISLVLDSVFYMGL--TLYFEKVLADKHGVKHEPLFFLKASYWSKEKPSPLM--------- 449

  Fly   446 ALLPLAGKNSEGNLPAAHPTRQPIIYLDDRTQENFQRVNISKKIGIEVRSLSKTFGFRN----VV 506
            |....:|::|.|:.....|                  .::..|..|.:..:.||:..::    .:
 Frog   450 AQTDDSGESSLGHFVEKVP------------------ADLHGKEAIRIHGVKKTYYDKDKNTEAL 496

  Fly   507 KDLFFNVYENEITALVGHKGSGKTTIIMMLCGILQPTTGTVLINGYDIVTEAKVA--KSSLGICP 569
            :||..|:||.:||||:||.|:||||::.:|.|:...:.|:..:..|.:.....:.  |..:|.||
 Frog   497 RDLDLNIYEGQITALLGHSGAGKTTLLNILSGMCPTSGGSATVCNYKLSNMRHLGEIKKRVGFCP 561

  Fly   570 QHSVIFKGMSARDHIYFFSRVKGYNKTEAMMESNIYISKLGLVDSQKWDAMRLSPGNQRRLSLAC 634
            |..:.|..::.::::..|:.:||....|...:....:|.|.:.|.:..:|.:||.|.:|:|:...
 Frog   562 QGDIKFDPLTVKENLTVFAMIKGIPSKEVAHKVQTVLSDLQMNDIENIEASKLSGGQKRKLTFGI 626

  Fly   635 ALCAGSKVILCDEPSSGLDPIGRHELMRFLQKEKHGRTILMTTQQLEEGEILADRIAIMNDGQIL 699
            |:....:|:|.|||::||||..||.:...|::.|..|..|::||.::|.:|||||..:::.|::.
 Frog   627 AILGDPQVLLLDEPTAGLDPCSRHNIWTILKESKADRVTLLSTQFMDEADILADRKVVISKGKLK 691

  Fly   700 CYGTLGYLKQLPFTSYTLSCQMAPNSKADNLTDLVRLYMTTTTSPVFHGVDVSYKLPRSQIDRFP 764
            |.||..:||:.....|.|..|::|:...:.:|.:::.::.:|.....:..:::|.||...:|.||
 Frog   692 CVGTSLFLKRKWGVGYHLRMQVSPSCDVELMTSIIKQHIPSTKLTTQNEEELTYTLPFENMDVFP 756

  Fly   765 EFFQQLEENKKSLNVVSFGVSDSTLDGIYLSLDYGQGSSRLRGGADPGVN-------DKVEFGVQ 822
            :.|..| :.:...::|::|||.:|||.::|.|   :|...:..|.....|       |:.:|..:
 Frog   757 DLFLHL-DGQVGNSIVNYGVSMTTLDDVFLKL---EGEGEIESGDYDVFNPESRTNEDREDFSTE 817

  Fly   823 TDKA-IRTKDRANNSLVRYQHQVDPPNETILNTKTPINPIEIWRPIDREKGSCMAQWQAMFIKKK 886
            .::: ::..|..|.:|..:                     |:||.      ..:|..:...:|.:
 Frog   818 MEESLLQMSDSGNVTLSGW---------------------ELWRQ------QVLAVARIRLLKLR 855

  Fly   887 NYTASRALIFILILIIPLFYYIIVLGT------AASEKCAHRTDKQPVLPLSLDYYSYDDMIILL 945
            :.|.|...|.:|:::|.|...||::.:      .|.|...|...:.|...|: .||:  |::|..
 Frog   856 HDTKSFRSILLLLVVITLPPIIIIITSNIVNTFDAWELTPHLYFQSPRNRLN-KYYT--DLLICN 917

  Fly   946 EVDKQLYKSEGEAYVQLVKEP-ATVESVDSIF-SHLLKAPPIIRRDIKRKYVCGASFNNASTITA 1008
            .....:     |.:|..|||. ..|:.|:..: :..:|....|......|   |.:|    ||.|
 Frog   918 NTGSSI-----EDFVGAVKEQNIEVQVVNGEYDTETVKYRGAIEVSQMEK---GYNF----TIVA 970

  Fly  1009 WFNSDAFEHSAPIALNLVYNALGKAVFEDQDFSILVNRGDLHDFIWLNNASSMRRRYKRQNDPDY 1073
              |..|| :|.|:.||::.|||.|         ||...|  |..:|              |.|..
 Frog   971 --NPKAF-NSLPVLLNIISNALLK---------ILKVSG--HFRVW--------------NHPIT 1007

  Fly  1074 TDYSDYEIQEYDVVVKPNSSSTSGQHNKSNPGDDNIITVQMSIIEAASTLYNEKGKRKQLFGTLI 1138
            ||                             |.|.|....||:|                   ..
 Frog  1008 TD-----------------------------GTDIIFLPYMSLI-------------------FF 1024

  Fly  1139 IITAYIALCLSIFSIFVTKERVEHFKMQQEIYGVTLFYFWSTHFVGDFLIYAIYMGALTIAIY-- 1201
            ||.| .|.|..| ::..|::...:.:.|..|.|:....:|....:.|.::|.|.: .|.:|||
 Frog  1025 IIFA-SAFCPHI-AMSSTEDNRINARNQLRISGLFPSAYWFGQALVDVILYWILL-FLMVAIYFA 1086

  Fly  1202 --HFTIWYQVVVMLLLIGF-----ACLPFVYLCSLLF--SLPNIAFAGIFAILVMTGGMLFSFMY 1257
              .:.:...|..|:::||.     |.:.:||:.|.:|  ...:.....:|.::..|..::|..::
 Frog  1087 FNSYILLDFVPAMVMIIGIIGYGTAMVLYVYVISFIFGRGKSHTDSWSLFFVITSTFPVMFMDVF 1151

  Fly  1258 MLTLITDVNFTTVFAILPMYVGTFGLFKCLAWREYCNR-EVLPPIEELDCKFGNCNVFCACKPER 1321
            |..|     ||..:.:.|. ....|:.      ||..| :|.|...|.......|..:
 Frog  1152 MFRL-----FTIYYFVFPA-SALSGIM------EYTYRLQVFPGGSEYTALIEQCTPY------- 1197

  Fly  1322 TWMEVWLLMVHCLVWFIFLWFS--NFG---------YEIGYRFKPKLSNRIWHNNEKHIRVLDEE 1375
                     :|.:::|:.|||.  .||         :.|..|......|.....|:....||.|:
 Frog  1198 ---------LHIIIFFVLLWFLEWKFGLRSLTIDPLFRISRRKITTKKNPEELGNDVDEDVLAEK 1253

  Fly  1376 RRVGLIPKYEH-EDYPIIV-DQVTKNYCRAKN----------AVQLVSFAIRPGDTFGLLGAQGA 1428
            .||.......: |:.|:|: |.:.|.|...|.          |.:.|||.::.|:..||||..||
 Frog  1254 ERVKKAATIANVEEKPVIIADSLRKEYKVKKGGSFFKKNKRAATKNVSFCVKKGEVLGLLGPNGA 1318

  Fly  1429 GKTSIFQMIAGETSMSHGNIYVRGHSLREHRNAAKMEVGFCPQGDNAPKYLTGRQLLRIHCLLHG 1493
            |||:...|:|||...:.|.:.:.|:.    ...:...:|:|||.:.....||.::.|.|:..:.|
 Frog  1319 GKTTSMYMLAGEVKPTAGEVLLCGND----PVGSTGFLGYCPQDNPLWPNLTVKEHLEIYAAVKG 1379

  Fly  1494 VPKDHIKAVSEQMAIEFNFKDQLDRPIHTYSGGKKRKLNIALA-IDSGSVLCLDDTNGSVDHATQ 1557
            :.|:.......::|.....|:.:.:.....|.|..||:..|:: :.:.:::.||:.:..:|...|
 Frog  1380 MKKEDASIAINRVASALELKEHMGKAARKLSLGVSRKVCFAISMLGNPNIVLLDEPSTGLDPKGQ 1444

  Fly  1558 RFIWRKLEAV-KRSGRPVLLTTQSMEEANAVCSRVAFLVAGEMMFIGSLQQVRSEVSNTIVIRLR 1621
            :.:||.:.|. |...|..:|||..||||.|||.|||.:|:|::..|||:||::|:.....::.::
 Frog  1445 QRLWRAIRAAFKNKDRGAILTTHYMEEAEAVCDRVAIMVSGKLRCIGSIQQLKSKFGKGYLLEIK 1509

  Fly  1622 VNPSDGKLKRRFQQLIADMAELFPLATLHEALETCLIYHINI-NVTTLANLFYQMEKIRNEGLLE 1685
            |..|     .:..|:..::..:||.|...:...:.|:|.|.: ||.:|:..|..:|:.:....:|
 Frog  1510 VKES-----HQVDQIHNEIIRIFPHAARQDRFSSLLVYKIPMDNVQSLSQAFLLLEEAKRAYNIE 1569

  Fly  1686 DYSITQVSLDEIYRILNDEEDPNLVDLDST 1715
            :||.:|.:|::::..|..|::....:|::|
 Frog  1570 EYSFSQSTLEQVFIELAKEQEKEDFELNNT 1599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31213	NP_001262752.1	ABC2_membrane_3	32..>295	CDD:289468	61/324 (19%)
		ABC_subfamily_A	491..708	CDD:213230	70/222 (32%)
		drrA	498..796	CDD:130256	93/303 (31%)
		ABC2_membrane_3	<1132..1285	CDD:289468	36/163 (22%)
		CcmA	1391..1672	CDD:224054	84/294 (29%)
		ABC_subfamily_A	1391..1609	CDD:213230	71/230 (31%)
abca10	XP_031750511.1	rim_protein	<107..1597	CDD:130324	411/1757 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D131191at2759
OrthoFinder	1	1.000	-	-		FOG0000051
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010