Protein Alignment CG31213 and abca5

DIOPT Version :9

• Sequence 1: NP_001262752.1
• Gene: CG31213 / 42382
• FlyBaseID: FBgn0051213
• Length: 1809
• Species: Drosophila melanogaster
• Sequence 2: NP_001135599.1
• Gene: abca5 / 100216156
• XenbaseID: XB-GENE-1012902
• Length: 1639
• Species: Xenopus tropicalis
• Alignment Length: 1860
• Identity: 410/1860 - (22%)
• Similarity: 768/1860 - (41%)
• Gaps: 402/1860 - (21%)

  Fly    15 LWKDIK-LQLTNWV-------ELVMIIFLSALMPIFFSIGTKVAKSIFPPDIEMEKSP------- 64
            |||..| |...|::       :.:..|    |.||.:.:.:.:..|:.......|..|
 Frog    10 LWKQTKTLLYKNYLIKCRTKRDSIQEI----LYPIIWWLISLLWASMVEQSKHYEAMPNTLLGGL 70

  Fly    65 -GPKSVNTSLFVDLYFTPNNGILEQLITQLAN--------ISEFKSVEVFDTNSELYLQLMINRN 120
             ||    :|..:.:.:||.:.|.:.::...|:        ...:...|...|.|..:     ..:
 Frog    71 DGP----SSRHLIIGYTPESNITQHIMAMTASECYLTDITFKPYLDEEHMKTASSSF-----EEH 126

  Fly   121 AIGIAFPSEW-----YDIKSCPEVLNLTIFMPLSIKRKD--------FKYFESGFLLLQERISKI 172
            .:|:.|.:..     :.:.|.|:   .|::|   ..|:|        .:||.|.|..||..|...
 Frog   127 FVGVVFDNAMSYKLRFSVYSVPD---STLYM---TPREDCHLWNCEASEYFYSTFTYLQACIDSS 185

  Fly   173 FIFFKNAGNGKIPRVLMNHFPYPSYVPNHYAESAKAMT------------YMTLISFFLPC---- 221
            .|..|.                 :|......:|.:|:.            |..|:|.||..
 Frog   186 MIKMKT-----------------NYSAWEELKSTRAVIMGEQEVIVVDTFYHALMSVFLVMAFSP 233

  Fly   222 --ITIAKYVVAEKERHQKAVLTAMGFSNSIHWLAW---YTKSMLLLLLCLLIMISIFSIGLIYEF 281
              .::|.|||.|||:..|..:..||..::..||.|   ||..:|::.|.:.::.:.|     :.|
 Frog   234 LGYSVAFYVVFEKEKKVKEFMKLMGLHDTAFWLPWVLLYTGFILVISLVMAVVATTF-----FPF 293

  Fly   282 SSLVCLMTIFLVYI---HSLVLFAFFISSFFSRSLSAVVATILMYFST----ALPFLIVGAEN-- 337
            |...|.: |||:|.   .||||||..::..|..|..   |..:::.||    |:...||..|:
 Frog   294 SKSNCFL-IFLLYALYGISLVLFALMLAPLFKNSKR---AGAIVFLSTLALGAVGIFIVLKEDFP 354

  Fly   338 ------SSVAAQTAASIGLNSALFYILDSVAVMEMQSVGAQWYTIDNTASSGYKLSIVGYMLIMI 396
                  .|...|....||:...|.        :|....|||:   .:.....|.|.|....|::.
 Frog   355 KSFVWFFSPFCQCTFMIGIAQVLH--------LEDFQRGAQF---THLKDGPYPLVITFIFLVVD 408

  Fly   397 SISWIELLICLYIEAVRTGEFEVPQPWSYPFQRRYWC--PLRYG---SSVFHQGALLPLAGKNSE 456
            |:.:  ||:..|::.|..||:.:.|...:..:..||.  ..|||   .|.|.:      |...||
 Frog   409 SVMY--LLLATYLDQVLPGEYGLRQSPFFFLKPSYWSKRKKRYGELNESYFDR------AVDMSE 465

  Fly   457 GNLPAAHPTRQPIIYLDDRTQENFQRVNISKKIGIEVRSLSKTFGF----RNVVKDLFFNVYENE 517
            ...|.:                    ..:..|..|.:..:.|:|..    ||.::.|.|::||.:
 Frog   466 VIEPVS--------------------AELHGKEAIRICCICKSFRKNNKPRNALQGLTFDIYEGQ 510

  Fly   518 ITALVGHKGSGKTTIIMMLCGILQPTTGTVLINGYDI--VTEAKVAKSSLGICPQHSVIFKGMSA 580
            |||||||.|:||||::.:|||:..||.|...:.|:.:  :.|.:.|....|||.|..:.|..::.
 Frog   511 ITALVGHSGTGKTTLMNILCGLCPPTEGFATVYGHRVTDIDEIQEASKMTGICQQTDIFFDVLTV 575

  Fly   581 RDHIYFFSRVKGYNKTEAMMESNIYISKLGLVDSQKWDAMRLSPGNQRRLSLACALCAGSKVILC 645
            .::::.|:.::|.::.....|.|..:..|.:...:...|..||.|.:|:||:|.|:....||:|.
 Frog   576 EENLHIFASLRGIDEKTKEQEINKILFDLDMQALKHNHARTLSIGQKRKLSVAIAVLGNPKVLLL 640

  Fly   646 DEPSSGLDPIGRHELMRFLQKEKHGRTILMTTQQLEEGEILADRIAIMNDGQILCYGTLGYLKQL 710
            |||::|:|...||.:...|:|.|.....:.:|..:||.:|||||.|:::.|.:.|.|:..:||..
 Frog   641 DEPTAGMDSCSRHTVWDLLKKRKGKHVTVFSTHCMEEADILADRKAVISQGSLKCIGSSLFLKSK 705

  Fly   711 PFTSYTLSCQMAPNSKADNLTDLVRLYMTTTTSPVFHGVDVSYKLPRSQIDRFPEFFQQLEENKK 775
            ....|.||..:......|.|:.|:..:::..:........:.|.||...:.:||..|..|:.. .
 Frog   706 WGVGYRLSMDIKKPCDVDALSSLITQHISGASLMQQSENSLLYSLPLKDVSKFPGLFSALDSG-S 769

  Fly   776 SLNVVSFGVSDSTLDGIYLSLDYGQGSSRLRGGADPGVNDKVEFGVQTDKAIRTKDRANNSLVRY 840
            .|.::::|||.:||:.::..|:                 .:.|.. |||.....::..:....:.
 Frog   770 DLGIITYGVSATTLEDVFFKLE-----------------TEAEID-QTDGIFNQRNLEDEGKWKS 816

  Fly   841 QHQVDPPNETILNTKTPINPIEIWRPIDREKGSCMAQWQAMFIKKKNY-----------TASRAL 894
            ...::   :.:|......:|..:       .||.:.:.|...:.|.::           .....|
 Frog   817 MEDIE---QGLLELSLESSPCSV-------TGSALWKQQVAAVAKLHFRNLHRESKSFRCVCLCL 871

  Fly   895 IFILILIIPLFYYIIVLGTAASEKCAHRTDKQPVLPLSLD-YYSYDDMIILLEVDKQLYKSEGEA 958
            :|.|:..:.|::    ||.:..:..|      |: .||.| |:|:.             |.:...
 Frog   872 LFFLVPQLTLYF----LGLSYHQSLA------PI-RLSADMYFSHP-------------KQKSHK 912

  Fly   959 YV-QLVKEPATVESVDSIFSHLLKAPPIIRRDIKRKYVCGASFNNAS---------------TIT 1007
            :: .|:.:.:|..::|.:..:|..      :.||...:.|:.:.:||               |..
 Frog   913 FLTSLLLQNSTGTNLDELLGNLNS------QKIKVDLINGSDYMSASPHNAALNVFLSGKHYTYE 971

  Fly  1008 AWFNSDAFEHSAPIALNLVYNALGKAVFEDQDFSILVNRGDLHDFIWLNNASSMRRRYKRQNDPD 1072
            |.||| :..||.|:.:|.:.|:|.:.:..::...           :|              |.|.
 Frog   972 AIFNS-SMVHSLPVLINTISNSLLRQLGVNESIE-----------VW--------------NSPF 1010

  Fly  1073 YTDY--SDYEIQEYDVVVKPNSSSTSGQHNKSNPGDDNIITVQMSIIEAASTLYNEKGKRKQLFG 1135
            |.|:  :.|.:..|.::...                 .|:|..:..| |....||.|
 Frog  1011 YQDFLHTSYGLDFYFLIAYL-----------------GIMTGMLPYI-AMENAYNHK-------- 1049

  Fly  1136 TLIIITAYIALCLSIFSIFVTKERVEHFKMQQEIYGVTLFYFWSTHFVGDFLIY--AIYMGALTI 1198
                :.||..|.::  .::.:.     :.:.|.:..:.||:......||..|.:  .|.:.|.|:
 Frog  1050 ----VKAYSQLKMA--GLYPSA-----YWVGQAVVDIPLFFLMLLFMVGSMLAFKSGIDLHAGTV 1103

  Fly  1199 AIYHFTIWYQVVVMLLLIGF--ACLPFVYLCSLLFSLPN---------IAFAGIFAILVMTGGML 1252
                      :.::..|||:  |.:...|:.|..:.|.|         .|.....:|:::...:.
 Frog  1104 ----------LAMIFCLIGYVPAVVLLTYVVSFTYKLINDTRQWWSLIFAVTASISIIIIEAAIF 1158

  Fly  1253 FSFMYMLTLITDVNFTTVFAILPMYVGTFGLFKCLAWREYCNREVLPPIEELDCKFGNCNVFCAC 1317
            |:....:|.: .|.|:..|.:.|:    .|...|..              ::.....:.:|....
 Frog  1159 FASSVTVTRL-HVFFSIFFPVYPL----LGCLTCFI--------------KMSRNLAHSDVKGLT 1204

  Fly  1318 KPERTWMEVWLLMVHCLVWFIFLWFSNFGY-------EIGYRFKPKLSNRIW------HNNEKHI 1369
            :..|..:.|:...||.|::|:.|.:....|       :..:|.:.| ..:.|      .:.::.:
 Frog  1205 QLGRLLVAVFAPYVHFLIFFLILRYLEMKYGGRSIRKDPVFRSQTK-KTKPWKFAEVPEDEDEDV 1268

  Fly  1370 RVLDEERRVGLIPKYEHEDYPIIV--------DQVTKNY---CRAKNAVQLVSFAIRPGDTFGLL 1423
            :|  |..|||.....:..:.|:::        ||..|..   ...|..|..|||.:|.|:|.||:
 Frog  1269 KV--ERARVGEYMAPDCNEKPMVLVSGLHKEQDQTGKTILGKAMRKLVVNNVSFCVRKGETVGLV 1331

  Fly  1424 GAQGAGKTSIFQMIAGETSMSHGNIYVRGHSLREHRNAAKMEVGFCPQGDNAPKYLTGRQLLRIH 1488
            |..||||:::..|:.|::.::.|.|.:...:..|...:....:|:.||.:.....:..::.|..:
 Frog  1332 GPNGAGKSTLLNMMVGQSELNAGQILMGDPAAGEPGLSPPRFLGYSPQTNYFWPEIKLQEHLETY 1396

  Fly  1489 CLLHGVPKDHIKAVSEQMAIEFNFKDQLDRPIHTYSGGKKRKLNIALA-IDSGSVLCLDDTNGSV 1552
            ..:.|:..:.:|.|:.::....:.||.|..|....|.|.:|||:.||: :.:..::.|::.:..:
 Frog  1397 GAIKGMGSNVLKEVTRRIVETLDLKDHLQEPAKKLSVGNQRKLSFALSMLGNPDIVLLEEPSTGM 1461

  Fly  1553 DHATQRFIWRKLE-AVKRSGRPVLLTTQSMEEANAVCSRVAFLVAGEMMFIGSLQQVRSEVSNTI 1616
            |...::.:|:.:. .:|...:..::||.|||||.|:|.|||.:|:|::.:|||:|.::|:.....
 Frog  1462 DPKNKQIMWKVIRTTLKGKEQAAVITTHSMEEAEAICDRVAIMVSGQLRYIGSVQHLKSKFGRYF 1526

  Fly  1617 VIRLRVNPSDGKLKRRFQQ---LIADMAELFPLATLHEALETCLIYHI-NINVTTLANLFYQMEK 1677
            .:.|:::     .:.|.|.   |..::.::||.|:..|:..:.:.|.: ..:|.:|:..|.::|:
 Frog  1527 SLELKLD-----TRARSQNVEFLHKEILQIFPNASHQESFSSLMSYKVPKEDVESLSQTFSKLEQ 1586

  Fly  1678 IRNEGLLEDYSITQVSLDEIYRIL--NDEEDPNLVDLDST 1715
            ::....:|:|..:|.:|::::..|  ..||:.|:..::||
 Frog  1587 VKQMYNIEEYIFSQATLEQVFIELAKEQEEEDNIATMNST 1626

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31213	NP_001262752.1	ABC2_membrane_3	32..>295	CDD:289468	66/312 (21%)
		ABC_subfamily_A	491..708	CDD:213230	74/222 (33%)
		drrA	498..796	CDD:130256	94/303 (31%)
		ABC2_membrane_3	<1132..1285	CDD:289468	29/165 (18%)
		CcmA	1391..1672	CDD:224054	75/297 (25%)
		ABC_subfamily_A	1391..1609	CDD:213230	63/230 (27%)
abca5	NP_001135599.1	rim_protein	<87..1616	CDD:130324	387/1763 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D131191at2759
OrthoFinder	1	1.000	-	-		FOG0000051
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010