Protein Alignment Hs6st and HS6ST1

DIOPT Version :10

• Sequence 1: NP_524409.2
• Gene: Hs6st / 42380
• FlyBaseID: FBgn0038755
• Length: 462
• Species: Drosophila melanogaster
• Sequence 2: NP_004798.3
• Gene: HS6ST1 / 9394
• HGNCID: 5201
• Length: 411
• Species: Homo sapiens
• Alignment Length: 300
• Identity: 166/300 - (55%)
• Similarity: 221/300 - (73%)
• Gaps: 5/300 - (1%)

  Fly   135 LNDDFQFDMDGHDVMVFLHIQKTGGTSFGRHLVRDLDLKRPCECQRQRKRCYCFRPHRNENWLFS 199
            |....:|||.|.||:|||||||||||:||||||:::.|:.||:|:..:|:|.|:||:|.|.||||
Human    75 LERSLRFDMKGDDVIVFLHIQKTGGTTFGRHLVQNVRLEVPCDCRPGQKKCTCYRPNRRETWLFS 139

  Fly   200 RYSTGWKCGLHADWTELTSCVDVELDKNEGETAK--RRYFYISLLRQPIARYMSEYRHVRRGATW 262
            |:||||.|||||||||||:||...||:.:....:  |:::||:|||.|::||:||:|||:|||||
Human   140 RFSTGWSCGLHADWTELTNCVPGVLDRRDSAALRTPRKFYYITLLRDPVSRYLSEWRHVQRGATW 204

  Fly   263 KGSRHWCLGRQATAAELPACYKGKDWLDVDLDQFAGCESNLAANRQTRMLADLALVGCYNKSSMP 327
            |.|.|.|.||..|..|||.||:|.||....|.:|..|..|||.|||.||||||:||||||.|.:|
Human   205 KTSLHMCDGRTPTPEELPPCYEGTDWSGCTLQEFMDCPYNLANNRQVRMLADLSLVGCYNLSFIP 269

  Fly   328 AHERDRVMLASAKRNLAAMAYFGLTEYQKMSQYIFEETFNLRFAIPFEQHNTTISATAVQNLRPD 392
            ..:|.:::|.|||:||..||:|||||:|:.:||:||.||||:|..||.|:|:| .|..|: :..|
Human   270 EGKRAQLLLESAKKNLRGMAFFGLTEFQRKTQYLFERTFNLKFIRPFMQYNST-RAGGVE-VDED 332

  Fly   393 QKRRIEKLNSLDIELYAFAKTLLFQRFEHLKAKDTNFEQR 432
            ..||||:||.||::||.:||.|..||:::.:..:.. |||
Human   333 TIRRIEELNDLDMQLYDYAKDLFQQRYQYKRQLERR-EQR 371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hs6st	NP_524409.2	Sulfotransfer_2	144..411	CDD:427369	154/268 (57%)
HS6ST1	NP_004798.3	Sulfotransfer_2	85..351	CDD:427369	154/267 (58%)